Data/hora: 23/06/2024 17:28:58

Biblioteca(s): | Embrapa Caprinos e Ovinos.
Data corrente: | 22/03/2005
Data da última atualização: | 10/06/2011
Autoria: | RODRIGUEZ-PIÑÓN, M.; TASENDE, C.; MEIKLE, A.; GARÓFALO, E. G.
Título: | Estrogen and progesterone receptors in the ovine cervix during the postpartum period.
Ano de publicação: | 2000
Fonte/Imprenta: | Theriogenology, v. 53, n. 3, p. 743-750, 2000.
Idioma: | Inglês
Conteúdo: | Cervical estrogen (E) and progesterone (P) receptors were characterized and quantified during the postpartum period in Corriedale ewes lambing in the late breeding season. Cervices and uteri were collected after ovariohystcrectomy at 1 d (n=2), 5 d (n=4), 17 d (n=2) or 30 d (n=2) post partum. The estrogen and progesterone rcceptors were measured using binding a says with tritiated hormones, dextran charcoal separation and inverse Scatchard analysis. Similar kinetic parameters in cytosolic binding sites for both hormones were found in ali cervical and uterine Samples, indicating that the binding protein in both tissues is of the same nature. Receptor concentrations (fmoVmg cytosolic protein) in the cervix of early (1 to 5 d, n=6) and late (17 to 30 d, n=4) postpartum ewes were 348+66 vs 994+145 (P<0.05) for E and 618+126 vs ll70+201 (P<0.05) for P, respectively. These data suggest an increased synthesis of receptors, probably due to the presence of ovarian estrogen-active follicles. Cervical E and Preceptor concentrations were similar or higher than those in lhe uterus(1.40+0.15, n=10 and 1.51l+0.19, n=10; for E and P respectively), and these receptor ratios did not differ between the early and Iate postpartum período. The high ratio between cervical/uterine receptors suggests that the ovine cervix may be a very sensitive to steroid action. ln conclusion, it was shown that restoration of steroid receptors during the postpartum period in the ovine cervix is similar to receptor dynamics in the uterus, and is probably associated with the recovery of ovarian cyclicity.
Palavras-Chave: | Atividade ovariana.
Thesagro: | Endocrinologia; Estrógeno; Ovelha; Ovino; Pós-Parto; Progesterona; Reprodução Animal.
Categoria do assunto: | --
Registro original: | Embrapa Caprinos e Ovinos (CNPC)
Exemplares: | CNPC - (17551-1) - ADC - AP - PP -  -  -  - DIS