| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Amazônia Ocidental. |
|
Data corrente: |
09/05/2023 |
|
Data da última atualização: |
01/09/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
PERES, E. G.; SOUZA, M. P.; SOUSA, T. F.; SILVA, C. V. A. da; BARROS, A. L.; SILVA, F. M. A. da; COSTA, E. V.; MEDEIROS, L. S. de; FORIM, M. R.; SOUZA, A. D. L. de; PAZ, W. H. P.; SILVA, G. F. da; SOUZA, A. Q. L. de; KOOLEN, H. H. F. |
|
Afiliação: |
ELDRINEI G. PERES, UNIVERSIDADE DO ESTADO DO AMAZONAS; MAYANE P. SOUZA, UNIVERSIDADE FEDERAL DO AMAZONAS; THIAGO F. SOUSA, UNIVERSIDADE DO ESTADO DO AMAZONAS; CARLOS V. A. DA SILVA, UNIVERSIDADE DO ESTADO DO AMAZONAS; ANDRÉ L. BARROS, UNIVERSIDADE DO ESTADO DO AMAZONAS; FELIPE M. A. DA SILVA, UNIVERSIDADE FEDERAL DO AMAZONAS; EMMANOEL V. COSTA, UNIVERSIDADE FEDERAL DO AMAZONAS; LÍVIA S. DE MEDEIROS, UNIVERSIDADE FEDERAL DE SÃO PAULO; MOACIR R. FORIM, UNIVERSIDADE FEDERAL DE SÃO CARLOS; AFONSO D. L. DE SOUZA, UNIVERSIDADE FEDERAL DO AMAZONAS; WEIDER H. P. PAZ, UNIVERSIDADE DO ESTADO DO AMAZONAS; GILVAN FERREIRA DA SILVA, CPAA; ANTONIA Q. L. DE SOUZA, UNIVERSIDADE FEDERAL DO AMAZONAS; HECTOR H. F. KOOLEN, UNIVERSIDADE DO ESTADO DO AMAZONAS. |
|
Título: |
Dereplication of sclerotiorin-like azaphilones produced by Penicillium meliponae using LC-MS/MS analysis and molecular networking. |
|
Ano de publicação: |
2023 |
|
Fonte/Imprenta: |
Journal of the Brazilian Chemical Society, v. 34, n. 8, p. 1139-1153, 2023. |
|
DOI: |
https://dx.doi.org/10.21577/0103-5053.20230027 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Penicillium meliponae, a recently described and rare species, was isolated as an endophytic fungus from the Amazonian plant Duguetia sthelechantha, and has been proven to be a pigment producer. Considering the high productivity of this species and the lack of data on its chemical composition, the present study aimed to characterize the chemical profile of P. meliponae and evaluate the influence of agitation and the use of different culture media. For this purpose, liquid chromatography coupled with mass spectrometry (LC-MS/MS) and molecular networking were used, allowing the identification of 17 azaphilone molecules with sclerotiorin-like skeletons, becoming the first chemical report of this species. In addition, the different production patterns in the tested culture media were indicative that this species is sensitive to changes in the composition of the carbon source and to the presence of agitation. Furthermore, this work contributes to the fragmentation mechanisms of the different possible structural arrangements for azaphilones of the sclerotiorin type and serves as a repository of information on the gas-phase behavior of this type of metabolite in mass spectrometry experiments and will assist future studies aimed at the discovery of azaphilones. |
|
Palavras-Chave: |
Azaphilones; Molecular networking; Penicillium meliponae. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1153604/1/2022-0285AR.pdf
|
|
Marc: |
LEADER 02310naa a2200325 a 4500
001 2153604
005 2023-09-01
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://dx.doi.org/10.21577/0103-5053.20230027$2DOI
100 1 $aPERES, E. G.
245 $aDereplication of sclerotiorin-like azaphilones produced by Penicillium meliponae using LC-MS/MS analysis and molecular networking.$h[electronic resource]
260 $c2023
520 $aPenicillium meliponae, a recently described and rare species, was isolated as an endophytic fungus from the Amazonian plant Duguetia sthelechantha, and has been proven to be a pigment producer. Considering the high productivity of this species and the lack of data on its chemical composition, the present study aimed to characterize the chemical profile of P. meliponae and evaluate the influence of agitation and the use of different culture media. For this purpose, liquid chromatography coupled with mass spectrometry (LC-MS/MS) and molecular networking were used, allowing the identification of 17 azaphilone molecules with sclerotiorin-like skeletons, becoming the first chemical report of this species. In addition, the different production patterns in the tested culture media were indicative that this species is sensitive to changes in the composition of the carbon source and to the presence of agitation. Furthermore, this work contributes to the fragmentation mechanisms of the different possible structural arrangements for azaphilones of the sclerotiorin type and serves as a repository of information on the gas-phase behavior of this type of metabolite in mass spectrometry experiments and will assist future studies aimed at the discovery of azaphilones.
653 $aAzaphilones
653 $aMolecular networking
653 $aPenicillium meliponae
700 1 $aSOUZA, M. P.
700 1 $aSOUSA, T. F.
700 1 $aSILVA, C. V. A. da
700 1 $aBARROS, A. L.
700 1 $aSILVA, F. M. A. da
700 1 $aCOSTA, E. V.
700 1 $aMEDEIROS, L. S. de
700 1 $aFORIM, M. R.
700 1 $aSOUZA, A. D. L. de
700 1 $aPAZ, W. H. P.
700 1 $aSILVA, G. F. da
700 1 $aSOUZA, A. Q. L. de
700 1 $aKOOLEN, H. H. F.
773 $tJournal of the Brazilian Chemical Society$gv. 34, n. 8, p. 1139-1153, 2023.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Gado de Leite. |
|
Data corrente: |
23/02/2023 |
|
Data da última atualização: |
06/09/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 2 |
|
Autoria: |
CARRARA, E. R.; PEIXOTO, M. G. C. D.; SILVA, A. A. da; BRUNELI, F. A. T.; VENTURA, H. T.; ZADRA, L. E. F.; JOSAHKIAN, L. A.; VERONEZE, R.; LOPES, P. S. |
|
Afiliação: |
EULA REGINA CARRARA, Universidade Federal de Viçosa; MARIA GABRIELA CAMPOLINA D PEIXOTO, CNPGL; ALESSANDRA ALVES DA SILVA, Universidade Estadual Paulista; FRANK ANGELO TOMITA BRUNELI, CNPGL; HENRIQUE TORRES VENTURA, Associação Brasileira dos Criadores de Zebu; LENIRA EL FARO ZADRA, Centro Brasileiro de Melhoramento Genético do Guzerá; LUIZ ANTÔNIO JOSAHKIAN, Associação Brasileira dos Criadores de Zebu; RENATA VERONEZE, Universidade Federal de Viçosa; PAULO SÁVIO LOPES, Universidade Federal de Viçosa. |
|
Título: |
Genomic prediction in Brazilian Guzerá cattle: application of a single-step approach to productive and reproductive traits. |
|
Ano de publicação: |
2023 |
|
Fonte/Imprenta: |
Tropical Animal Health and Production, v. 55, article 48, 2023. |
|
DOI: |
https://doi.org/10.1007/s11250-023-03484-9 |
|
Idioma: |
Inglês |
|
Conteúdo: |
This study aimed to investigate the feasibility of genomic prediction for productive and reproductive traits in Guzerá cattle using single-step genomic best linear unbiased prediction (ssGBLUP). Evaluations included the 305-day cumulative yields (frst lactation, in kg) of milk, lactose, protein, fat, and total solids; adjusted body weight (kg) at the ages of 450, 365, and 210 days; and age at frst calving (in days), from a database containing 197,283 measurements from Guzerá males and females born between 1954 and 2018. The pedigree included 433,823 animals spanning up to 14 overlapping generations. A total of 1618 animals were genotyped. The analyses were performed using ssGBLUP and traditional BLUP methods. Predictive ability and bias were accessed using cross-validation: predictive ability was similar between the methods and ranged from 0.27 to 0.47 for the genomic-based model and from 0.30 to 0.45 for the pedigree-based model; the bias was also similar between the methods, ranging from 0.88 to 1.35 in the genomic-based model and from 0.96 to 1.41 in the pedigree-based model. The individual accuracies of breeding values were evidently increased in the genomic evaluation, with values ranging from 0.41 to 0.56 in the genomic-based model and from 0.26 to 0.54 in the pedigree-based model. Even based on a small number of genotyped animals and a small database for some traits, the results suggest that ssGBLUP is feasible and may be applied to national genetic evaluation of the breed to increase the accuracy of breeding values without greatly impacting predictive ability and bias. MenosThis study aimed to investigate the feasibility of genomic prediction for productive and reproductive traits in Guzerá cattle using single-step genomic best linear unbiased prediction (ssGBLUP). Evaluations included the 305-day cumulative yields (frst lactation, in kg) of milk, lactose, protein, fat, and total solids; adjusted body weight (kg) at the ages of 450, 365, and 210 days; and age at frst calving (in days), from a database containing 197,283 measurements from Guzerá males and females born between 1954 and 2018. The pedigree included 433,823 animals spanning up to 14 overlapping generations. A total of 1618 animals were genotyped. The analyses were performed using ssGBLUP and traditional BLUP methods. Predictive ability and bias were accessed using cross-validation: predictive ability was similar between the methods and ranged from 0.27 to 0.47 for the genomic-based model and from 0.30 to 0.45 for the pedigree-based model; the bias was also similar between the methods, ranging from 0.88 to 1.35 in the genomic-based model and from 0.96 to 1.41 in the pedigree-based model. The individual accuracies of breeding values were evidently increased in the genomic evaluation, with values ranging from 0.41 to 0.56 in the genomic-based model and from 0.26 to 0.54 in the pedigree-based model. Even based on a small number of genotyped animals and a small database for some traits, the results suggest that ssGBLUP is feasible and may be applied to national genetic evaluation of the ... Mostrar Tudo |
|
Palavras-Chave: |
Predição genômica. |
|
Thesagro: |
Bovino; Gado Guzerá; Raça; Reprodução Animal. |
|
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
|
Marc: |
LEADER 02508naa a2200289 a 4500
001 2151876
005 2023-09-06
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1007/s11250-023-03484-9$2DOI
100 1 $aCARRARA, E. R.
245 $aGenomic prediction in Brazilian Guzerá cattle$bapplication of a single-step approach to productive and reproductive traits.$h[electronic resource]
260 $c2023
520 $aThis study aimed to investigate the feasibility of genomic prediction for productive and reproductive traits in Guzerá cattle using single-step genomic best linear unbiased prediction (ssGBLUP). Evaluations included the 305-day cumulative yields (frst lactation, in kg) of milk, lactose, protein, fat, and total solids; adjusted body weight (kg) at the ages of 450, 365, and 210 days; and age at frst calving (in days), from a database containing 197,283 measurements from Guzerá males and females born between 1954 and 2018. The pedigree included 433,823 animals spanning up to 14 overlapping generations. A total of 1618 animals were genotyped. The analyses were performed using ssGBLUP and traditional BLUP methods. Predictive ability and bias were accessed using cross-validation: predictive ability was similar between the methods and ranged from 0.27 to 0.47 for the genomic-based model and from 0.30 to 0.45 for the pedigree-based model; the bias was also similar between the methods, ranging from 0.88 to 1.35 in the genomic-based model and from 0.96 to 1.41 in the pedigree-based model. The individual accuracies of breeding values were evidently increased in the genomic evaluation, with values ranging from 0.41 to 0.56 in the genomic-based model and from 0.26 to 0.54 in the pedigree-based model. Even based on a small number of genotyped animals and a small database for some traits, the results suggest that ssGBLUP is feasible and may be applied to national genetic evaluation of the breed to increase the accuracy of breeding values without greatly impacting predictive ability and bias.
650 $aBovino
650 $aGado Guzerá
650 $aRaça
650 $aReprodução Animal
653 $aPredição genômica
700 1 $aPEIXOTO, M. G. C. D.
700 1 $aSILVA, A. A. da
700 1 $aBRUNELI, F. A. T.
700 1 $aVENTURA, H. T.
700 1 $aZADRA, L. E. F.
700 1 $aJOSAHKIAN, L. A.
700 1 $aVERONEZE, R.
700 1 $aLOPES, P. S.
773 $tTropical Animal Health and Production$gv. 55, article 48, 2023.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
