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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sul; Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
27/09/2017 |
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Data da última atualização: |
28/09/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
CAVALCANTI, L. C. G.; MORAES, J. C. F.; FARIA, D. A. de; MCMANUS, C. M.; NEPOMUCENO, A. R.; SOUZA, C. J. H. de; CAETANO, A. R.; PAIVA, S. R. |
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Afiliação: |
Lilian Cristina Gomes Cavalcanti, UNB; JOSE CARLOS FERRUGEM MORAES, CPPSUL; Danielle Asis de Faria, CENARGEN; Concepta Margaret McManus, UNB; Alcebiades Renato Nepomuceno, UNB; CARLOS JOSE HOFF DE SOUZA, CPPSUL; ALEXANDRE RODRIGUES CAETANO, Cenargen; SAMUEL REZENDE PAIVA, Cenargen. |
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Título: |
Genetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Agropecuária Brasileira, Brasília, DF, v. 52, n. 8, p. 615-622, ago. 2017. |
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DOI: |
10.1590/S0100-204X2017000800007 |
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Idioma: |
Inglês |
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Notas: |
Título em português: Caracterização genética de genes para cor da pelagem do núcleo de conservação da ovelha Crioula no Brasil. |
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Conteúdo: |
The objective of this work was to identify single nucleotide polymorphisms (SNPs) in resequencing data from MC1R, ASIP, and TYRP1 genes derived from Crioula sheep (Ovis aris) with different coat colors. Polymorphisms in the ASIP (agouti-signaling protein), MC1R (melanocortin 1 receptor), and TRYP1 (tyrosinase-related protein 1) genes were analyzed in 115 sheep from Embrapa?s conservation nucleus of crioula sheep, in Brazil. A total of 7,914 bp were sequenced per animal, and 14 SNPs were identified. Two additional assays were performed to detect duplications and deletions in the ASIP gene. Ninety-five percent of the coat color variation was explained by epistatic interactions observed between specific alleles in the MC1R and ASIP genes. Evidence suggests an important role of TYRP1 variants for wool color, despite their low frequencies. The marker panel was efficient enough in predicting coat color in the studied animals and, therefore, can be used to implement a marker-assisted selection program in the conservation nucleus of sheep of the crioula breed. |
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Palavras-Chave: |
ASIP; Conservação de recurso genético; Genetic resources conservation; MC1R; Ovis aris; Seleção assistida por marcadores; TYRP1. |
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Thesagro: |
Ovino. |
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Thesaurus Nal: |
Marker-assisted selection. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/163749/1/Genetic-characterization-of-coat-color.pdf
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Marc: |
LEADER 02240naa a2200337 a 4500
001 2076385
005 2017-09-28
008 2017 bl --- 0-- u #d
024 7 $a10.1590/S0100-204X2017000800007$2DOI
100 1 $aCAVALCANTI, L. C. G.
245 $aGenetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus.$h[electronic resource]
260 $c2017
500 $aTítulo em português: Caracterização genética de genes para cor da pelagem do núcleo de conservação da ovelha Crioula no Brasil.
520 $aThe objective of this work was to identify single nucleotide polymorphisms (SNPs) in resequencing data from MC1R, ASIP, and TYRP1 genes derived from Crioula sheep (Ovis aris) with different coat colors. Polymorphisms in the ASIP (agouti-signaling protein), MC1R (melanocortin 1 receptor), and TRYP1 (tyrosinase-related protein 1) genes were analyzed in 115 sheep from Embrapa?s conservation nucleus of crioula sheep, in Brazil. A total of 7,914 bp were sequenced per animal, and 14 SNPs were identified. Two additional assays were performed to detect duplications and deletions in the ASIP gene. Ninety-five percent of the coat color variation was explained by epistatic interactions observed between specific alleles in the MC1R and ASIP genes. Evidence suggests an important role of TYRP1 variants for wool color, despite their low frequencies. The marker panel was efficient enough in predicting coat color in the studied animals and, therefore, can be used to implement a marker-assisted selection program in the conservation nucleus of sheep of the crioula breed.
650 $aMarker-assisted selection
650 $aOvino
653 $aASIP
653 $aConservação de recurso genético
653 $aGenetic resources conservation
653 $aMC1R
653 $aOvis aris
653 $aSeleção assistida por marcadores
653 $aTYRP1
700 1 $aMORAES, J. C. F.
700 1 $aFARIA, D. A. de
700 1 $aMCMANUS, C. M.
700 1 $aNEPOMUCENO, A. R.
700 1 $aSOUZA, C. J. H. de
700 1 $aCAETANO, A. R.
700 1 $aPAIVA, S. R.
773 $tPesquisa Agropecuária Brasileira, Brasília, DF$gv. 52, n. 8, p. 615-622, ago. 2017.
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Embrapa Pecuária Sul (CPPSUL) |
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