| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
|
Data corrente: |
16/06/2017 |
|
Data da última atualização: |
16/06/2017 |
|
Autoria: |
MARTIN, G. B.; TAYLOR, P. L.; McNEILLY, A. S. |
|
Título: |
Effect of small doses of bovine follicular fluid on the tonic secretion of gonadotrophins in the ewe. |
|
Ano de publicação: |
1987 |
|
Fonte/Imprenta: |
Journal of Endocrinology, v. 114, n. 1, p. 73-79, Jul. 1987. |
|
DOI: |
10.1677/joe.0.1140073 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract: Previous work has shown that treatment of ewes with steroid-free bovine follicular fluid (bFF), a rich source of inhibin, partially inhibits the increase in mean plasma concentrations of LH induced by ovariectomy. The present experiment was designed to test the hypothesis that this effect was a reflection of reduced LH pulse amplitude which would only be expressed at high (pharmacological) doses of bFF. To do this, we assessed the dose-response to bFF of the secretion of FSH and LH pulses in intact and acutely ovariectomized ewes. In intact ewes, a low dose of bFF (0.2 ml s.c. every 8 h) had no detectable effect on the secretion of FSH, an intermediate dose (0.6 ml s.c. every 8 h) depressed FSH concentrations for about 24 h and a high dose (1.8 ml s.c. every 8 h) reduced FSH concentrations to undetectable levels. In ewes treated with 1.8 ml bFF, FSH concentrations also remained undetectable after ovariectomy and did not increase until treatment was withdrawn. In ewes treated with 0.6 ml bFF, FSH concentrations were maintained at normal intact levels for about 32 h following ovariectomy but then rose to normal ovariectomized levels. In ewes treated with 0.2 ml bFF, FSH concentrations increased immediately after ovariectomy but more slowly than in control ovariectomized ewes. Profiles of LH pulses were recorded after ovariectomy, during and after the withdrawal of bFF treatment. In ewes treated with the highest dose (1.8 ml s.c. every 8 h), mean LH levels and pulse amplitude were lower than in control ewes and increased significantly following withdrawal of treatment. MenosAbstract: Previous work has shown that treatment of ewes with steroid-free bovine follicular fluid (bFF), a rich source of inhibin, partially inhibits the increase in mean plasma concentrations of LH induced by ovariectomy. The present experiment was designed to test the hypothesis that this effect was a reflection of reduced LH pulse amplitude which would only be expressed at high (pharmacological) doses of bFF. To do this, we assessed the dose-response to bFF of the secretion of FSH and LH pulses in intact and acutely ovariectomized ewes. In intact ewes, a low dose of bFF (0.2 ml s.c. every 8 h) had no detectable effect on the secretion of FSH, an intermediate dose (0.6 ml s.c. every 8 h) depressed FSH concentrations for about 24 h and a high dose (1.8 ml s.c. every 8 h) reduced FSH concentrations to undetectable levels. In ewes treated with 1.8 ml bFF, FSH concentrations also remained undetectable after ovariectomy and did not increase until treatment was withdrawn. In ewes treated with 0.6 ml bFF, FSH concentrations were maintained at normal intact levels for about 32 h following ovariectomy but then rose to normal ovariectomized levels. In ewes treated with 0.2 ml bFF, FSH concentrations increased immediately after ovariectomy but more slowly than in control ovariectomized ewes. Profiles of LH pulses were recorded after ovariectomy, during and after the withdrawal of bFF treatment. In ewes treated with the highest dose (1.8 ml s.c. every 8 h), mean LH levels and pulse a... Mostrar Tudo |
|
Palavras-Chave: |
Drug effects; FSH; LH; Ovaries; Secretory Rate; Time Factors. |
|
Thesaurus Nal: |
Body fluids; Ovariectomy; Physiology; Sheep. |
|
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
|
Marc: |
LEADER 02349naa a2200277 a 4500
001 2071035
005 2017-06-16
008 1987 bl uuuu u00u1 u #d
024 7 $a10.1677/joe.0.1140073$2DOI
100 1 $aMARTIN, G. B.
245 $aEffect of small doses of bovine follicular fluid on the tonic secretion of gonadotrophins in the ewe.
260 $c1987
520 $aAbstract: Previous work has shown that treatment of ewes with steroid-free bovine follicular fluid (bFF), a rich source of inhibin, partially inhibits the increase in mean plasma concentrations of LH induced by ovariectomy. The present experiment was designed to test the hypothesis that this effect was a reflection of reduced LH pulse amplitude which would only be expressed at high (pharmacological) doses of bFF. To do this, we assessed the dose-response to bFF of the secretion of FSH and LH pulses in intact and acutely ovariectomized ewes. In intact ewes, a low dose of bFF (0.2 ml s.c. every 8 h) had no detectable effect on the secretion of FSH, an intermediate dose (0.6 ml s.c. every 8 h) depressed FSH concentrations for about 24 h and a high dose (1.8 ml s.c. every 8 h) reduced FSH concentrations to undetectable levels. In ewes treated with 1.8 ml bFF, FSH concentrations also remained undetectable after ovariectomy and did not increase until treatment was withdrawn. In ewes treated with 0.6 ml bFF, FSH concentrations were maintained at normal intact levels for about 32 h following ovariectomy but then rose to normal ovariectomized levels. In ewes treated with 0.2 ml bFF, FSH concentrations increased immediately after ovariectomy but more slowly than in control ovariectomized ewes. Profiles of LH pulses were recorded after ovariectomy, during and after the withdrawal of bFF treatment. In ewes treated with the highest dose (1.8 ml s.c. every 8 h), mean LH levels and pulse amplitude were lower than in control ewes and increased significantly following withdrawal of treatment.
650 $aBody fluids
650 $aOvariectomy
650 $aPhysiology
650 $aSheep
653 $aDrug effects
653 $aFSH
653 $aLH
653 $aOvaries
653 $aSecretory Rate
653 $aTime Factors
700 1 $aTAYLOR, P. L.
700 1 $aMcNEILLY, A. S.
773 $tJournal of Endocrinology$gv. 114, n. 1, p. 73-79, Jul. 1987.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 3 | |
| 1. |  | KELLEY, B. S.; LEE, S.-J.; DAMASCENO, C. M. B.; CHAKRAVARTHY, S.; KIM, B.-D.; MARTIN, G. B.; ROSE, J. K. C. A secreted effector protein (SNE1) from Phytophthora infestans is a broadly acting suppressor of programmed cell death. The Plant Journal, v. 62, p. 357-366, 2010.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Milho e Sorgo. |
|    |
| 2. | | RIVERO, M. J.; LOPEZ-VILALOBOS, N.; EVANS, A.; BERNDT, A.; CARTMILL, A.; NEAL, A. L.; MCLAREN, A.; FARRUGGIA, A.; MIGNOLET, C.; CHADWICK, D.; MCCRACKEN, D.; BUSCH, D.; MARTIN, G. B.; FLEMING, H.; SHERIDAN, H.; GIBBONS, J.; MERBOLD, L.; EISLER, M.; LAMBE, N.; ROVIRA, P.; HARRIS, P.; MURPHY, P.; VERCOE, P. E.; WILLIAMS, P.; MACHADO, R.; TAKAHASHI, T.; PUECH, T.; BOLAND, T.; AYALA, W.; LEE, M. R. F. Key traits for ruminant livestock across diverse production systems in the context of climate change: perspectives from a global platform of research farms. Reproduction, Fertility and Development, v. 33, p. 1-19, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
|  |
| 3. | | RIVERO, M. J.; EVANS, A. C. O.; BERNDT, A.; CARTMILL, A.; DOWSEY, A.; FARRUGGIA, A.; MIGNOLET, C.; ENRIQUEZ-HIDALGO, D.; CHADWICK, D.; MCCRACKEN, D. I.; BUSCH, D.; PEREYRA, F.; MARTIN, G. B.; SANFORD, G. R.; SHERIDAN, H.; WRIGHT, I.; BRUNET, L.; EISLER, M. C.; LOPEZ-VILLALOBOS, N.; ROVIRA, P.; HARRIS, P.; MURPHY, P.; WILLIAMS, A. P.; JACKSON, R. D.; MACHADO, R.; SURAJ, P. T.; PUECH, T.; BOLAND, T. M.; AYALA, W.; LEE, M. R. F. Taking the steps toward sustainable livestock: our multidisciplinary global farm platform journey. Animal Frontiers, v.11, n.5, p.52-58, oct. 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 5 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
| Registros recuperados : 3 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
