Data/hora: 23/06/2024 22:00:49

Biblioteca(s): 	Embrapa Caprinos e Ovinos.	
Data corrente: 	01/08/1992	
Data da última atualização: 	04/12/2023	
Autoria: 	PEPIN, M.; PARDON, P.; MARLY, J.; LANTIER, F.	
Título: 	Corynebacterium pseudotuberculosis infection in adult ewes by inoculation in the external ear.	
Ano de publicação: 	1988	
Fonte/Imprenta: 	American Journal of Veterinary Research, v. 49, n. 4, p. 459-463, Apr. 1988.	
Idioma: 	Inglês	
Conteúdo: 	Abstract: Caseous lymphadenitis, caused by Corynebacterium pseudotuberculosis, was studied in ewes to devise a reliable method of induced infection that would help to understand mechanisms by which abscesses develop in lymph nodes or internal organs, especially the lungs. Fifteen adult ewes, from a flock where the occurrence of caseous lymphadenitis was unknown, were inoculated SC in the auricle with various doses of a virulent strain of C pseudotuberculosis. Ewes inoculated with at least 10(8) viable corynebacteria develop a strong local reaction that was apparent 4 hours after challenge exposure and lasted 7 to 14 days. Of these ewes, all developed at least 1 abscess and 3 developed multiple abscesses in lymph nodes draining the inoculated auricle and in the lungs. All infected ewes developed a strong antibody response against C pseudotuberculosis exotoxin, which persisted for 3 months. Of 9 ewes infected with 1.2 X 10(8) corynebacteria, 3 developed lesions because of field strains of C pseudotuberculosis and had an increased capacity to limit the dissemination of challenge-inoculum bacteria by developing only one abscess in the draining lymph node (parotid or prescapular lymph node). Seemingly, inoculation in the external ear was a suitable method for obtaining a reproducible infection and indicated that a primary infection might protect against reinfection by limiting dissemination of C pseudotuberculosis.	
Palavras-Chave: 	Linfadenie caseosa.	
Thesagro: 	Doença; Ovino.	
Thesaurus Nal: 	Abscess; Bacterial antibodies; Caseous lymphadenitis; Ear diseases; Ewes; Females; Sheep diseases.	
Categoria do assunto: 	H Saúde e Patologia	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPC - (6655-1) - ADD - AP - DD -  -  -  - DIS