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 | Acesso ao texto completo restrito à biblioteca da Embrapa Florestas. Para informações adicionais entre em contato com cnpf.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Florestas. |
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Data corrente: |
07/06/2019 |
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Data da última atualização: |
30/10/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LIMA, G. G. de; CHEE, B. S.; MORITZ, V. F.; CORTESE, Y. J.; MAGALHAES, W. L. E.; DEVINE, D. M.; NUGENT, M. J. D. |
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Afiliação: |
Gabriel Goetten de Lima, Materials Research Institute, Athlone Institute of Technology; Bor Shin Chee, Materials Research Institute, Athlone Institute of Technology; Vicente Froés Moritz, Materials Research Institute, Athlone Institute of Technology; Yvonne J Cortese, Materials Research Institute, Athlone Institute of Technology; WASHINGTON LUIZ ESTEVES MAGALHAES, CNPF; Declan M Devine, Materials Research Institute, Athlone Institute of Technology; Michael J D Nugent, Materials Research Institute, Athlone Institute of Technology. |
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Título: |
The production of a novel poly(vinyl alcohol) hydrogel cryogenic spheres for immediate release using a droplet system. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
Biomedical Physics & Engineering Express, v. 5, n. 4, 045017, Jul. 2019. 13 p. |
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DOI: |
10.1088/2057-1976/ab2547 |
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Idioma: |
Inglês |
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Conteúdo: |
Although freeze-thaw mechanism for producing crosslinked hydrogels is relatively easy and simple, it lacks sufficient integrity and support leading to modifications on its three-dimensional polymeric network arrangement during water removal?drying. Therefore, a strengthening method for obtaining cryogenic spheres of polyvinyl alcohol hydrogels is purposed by dispensing it as liquid droplets into a low temperature solution followed by a modification on its freeze-thaw cycles to confer a good geometry without aggregation. Various materials were incorporated into this hydrogel structure, including poly(acrylic acid) to impart pH sensitivity; hydroxyapatite to improve biocompatibility; and ciprofloxacin as an antimicrobial agent relevant for the treatment of osteomyelitis. The overall network presented a porous structure with a fibrous-like pattern which varied in size and volume, with presence of Ca and P when hydroxyapatite is incorporated. These materials varied the crystalline melting point of the poly(vinyl alcohol) and a linear pHsensitivity function was obtained by the addition of the materials. These hydrogels were found to release ciprofloxacin within 60 min and were able to dissolve at the same time intervals. Therefore, the hydrogel synthesised in this work can be used as an immediate release drug delivery mechanism for the in situ delivery of active pharmaceutical such as ciprofloxacin for a treatment of osteomyelitis. |
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Palavras-Chave: |
Álcool polivinílico; Immediate releas; Liberação de fármaco por via oral; Oral drug delivery; PH-sensitivity; Produto madeireiro. |
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Thesaurus Nal: |
Polyvinyl alcohol. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 02387naa a2200289 a 4500
001 2109732
005 2019-10-30
008 2019 bl uuuu u00u1 u #d
024 7 $a10.1088/2057-1976/ab2547$2DOI
100 1 $aLIMA, G. G. de
245 $aThe production of a novel poly(vinyl alcohol) hydrogel cryogenic spheres for immediate release using a droplet system.$h[electronic resource]
260 $c2019
520 $aAlthough freeze-thaw mechanism for producing crosslinked hydrogels is relatively easy and simple, it lacks sufficient integrity and support leading to modifications on its three-dimensional polymeric network arrangement during water removal?drying. Therefore, a strengthening method for obtaining cryogenic spheres of polyvinyl alcohol hydrogels is purposed by dispensing it as liquid droplets into a low temperature solution followed by a modification on its freeze-thaw cycles to confer a good geometry without aggregation. Various materials were incorporated into this hydrogel structure, including poly(acrylic acid) to impart pH sensitivity; hydroxyapatite to improve biocompatibility; and ciprofloxacin as an antimicrobial agent relevant for the treatment of osteomyelitis. The overall network presented a porous structure with a fibrous-like pattern which varied in size and volume, with presence of Ca and P when hydroxyapatite is incorporated. These materials varied the crystalline melting point of the poly(vinyl alcohol) and a linear pHsensitivity function was obtained by the addition of the materials. These hydrogels were found to release ciprofloxacin within 60 min and were able to dissolve at the same time intervals. Therefore, the hydrogel synthesised in this work can be used as an immediate release drug delivery mechanism for the in situ delivery of active pharmaceutical such as ciprofloxacin for a treatment of osteomyelitis.
650 $aPolyvinyl alcohol
653 $aÁlcool polivinílico
653 $aImmediate releas
653 $aLiberação de fármaco por via oral
653 $aOral drug delivery
653 $aPH-sensitivity
653 $aProduto madeireiro
700 1 $aCHEE, B. S.
700 1 $aMORITZ, V. F.
700 1 $aCORTESE, Y. J.
700 1 $aMAGALHAES, W. L. E.
700 1 $aDEVINE, D. M.
700 1 $aNUGENT, M. J. D.
773 $tBiomedical Physics & Engineering Express$gv. 5, n. 4, 045017, Jul. 2019. 13 p.
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Registro original: |
Embrapa Florestas (CNPF) |
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Origem |
Tipo/Formato |
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Registro |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Amazônia Oriental. Para informações adicionais entre em contato com cpatu.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Amazônia Oriental. |
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Data corrente: |
24/08/2021 |
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Data da última atualização: |
15/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
PEREIRA, D. S.; OLIVEIRA, M. S. de; CRUZ, J. N.; BEZERRA, P. do N.; SILVA, A. G. da; PEREIRA, N. S.; PORTS, P. S.; SOUZA FILHO, A. P. da S.; MARACAJÁ, P. B.; FREITAS, M. O.; FREITAS, C. I. A. |
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Afiliação: |
DANIEL SANTIAGO PEREIRA, CPATU; MOZANIEL SANTANA DE OLIVEIRA, MPEG; JORDDY NEVES CRUZ, MPEG; PRISCILA DO NASCIMENTO BEZERRA, MPEG; ADRIANE GOMES DA SILVA, FIBRA / MPEG; NATANAEL SANTIAGO PEREIRA, IFCE; POLLYANE S. PORTS, FIBRA; ANTONIO PEDRO DA SILVA SOUZA FILHO, CPATU; PATRÍCIO BORGES MARACAJÁ, Universidade Federal Rural do Semiárido; MARINALVA OLIVEIRA FREITAS, Universidade Federal Rural do Semiárido; CARLOS IBERÊ ALVES FREITAS, UNIVERSIDADE FEDERAL DE CAMPINA GRANDE / Universidade Federal Rural do Semiárido. |
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Título: |
Herbicidal potential (phytotoxic) of honey bee propolis extracts of the Brazilian northeast on weeds of cultivated pastures. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Journal of Apicultural Research, v. 63, n. 1, p. 112-121, 2024. |
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DOI: |
https://doi.org/10.1080/00218839.2021.1957611 |
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Idioma: |
Inglês |
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Notas: |
Published online: 24 Aug 2021. |
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Conteúdo: |
Propolis is made up of complex mixtures of substances made by bees and has shown great potential for use in diverse human applications over the years, but studies reporting its herbicidal activity are still very scarce in the literature. This study aimed to characterize the chemical composition and the allelopathic potential activities of different propolis types from the state of Rio Grande do Norte, Brazil. The extracts mixed in eluent 80% ethanol were tested on the seed germination and the growth of the radicle and hypocotyl weed areas of cultivated Mimosa pudica and Senna obtusifolia pastures. The extracts exhibited that the allelopathic activity intensities varied with the concentration, origin of the propolis, receptor plant, and examined plant part. The intensities of the inhibitions were positively associated with the concentration, reaching maximal inhibitions verified at 0.75% and 1.0%. The inhibition of germination was the most noticeably influenced factor. Malice was the test plant most sensitive to the effects of the extracts. In comparison, the extract of red propolis showed greater potential to inhibit the germination and development of the two receptor plants, particularly the seed germination, when the differences were most striking. |
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Thesagro: |
Abelha; Alelopatia; Fitotoxicidade; Própolis. |
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Categoria do assunto: |
O Insetos e Entomologia |
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Marc: |
LEADER 02254naa a2200313 a 4500
001 2133830
005 2024-02-15
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1080/00218839.2021.1957611$2DOI
100 1 $aPEREIRA, D. S.
245 $aHerbicidal potential (phytotoxic) of honey bee propolis extracts of the Brazilian northeast on weeds of cultivated pastures.$h[electronic resource]
260 $c2024
500 $aPublished online: 24 Aug 2021.
520 $aPropolis is made up of complex mixtures of substances made by bees and has shown great potential for use in diverse human applications over the years, but studies reporting its herbicidal activity are still very scarce in the literature. This study aimed to characterize the chemical composition and the allelopathic potential activities of different propolis types from the state of Rio Grande do Norte, Brazil. The extracts mixed in eluent 80% ethanol were tested on the seed germination and the growth of the radicle and hypocotyl weed areas of cultivated Mimosa pudica and Senna obtusifolia pastures. The extracts exhibited that the allelopathic activity intensities varied with the concentration, origin of the propolis, receptor plant, and examined plant part. The intensities of the inhibitions were positively associated with the concentration, reaching maximal inhibitions verified at 0.75% and 1.0%. The inhibition of germination was the most noticeably influenced factor. Malice was the test plant most sensitive to the effects of the extracts. In comparison, the extract of red propolis showed greater potential to inhibit the germination and development of the two receptor plants, particularly the seed germination, when the differences were most striking.
650 $aAbelha
650 $aAlelopatia
650 $aFitotoxicidade
650 $aPrópolis
700 1 $aOLIVEIRA, M. S. de
700 1 $aCRUZ, J. N.
700 1 $aBEZERRA, P. do N.
700 1 $aSILVA, A. G. da
700 1 $aPEREIRA, N. S.
700 1 $aPORTS, P. S.
700 1 $aSOUZA FILHO, A. P. da S.
700 1 $aMARACAJÁ, P. B.
700 1 $aFREITAS, M. O.
700 1 $aFREITAS, C. I. A.
773 $tJournal of Apicultural Research$gv. 63, n. 1, p. 112-121, 2024.
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Embrapa Amazônia Oriental (CPATU) |
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