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Registro Completo
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
29/08/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
PIMENTEL, M. M. L.; SANTOS, F. A.; TEIXEIRA, A. C. G.; IZZO, R. G.; LIMA, M. A.; MACEDFO, M. F.; BEZERRA, M. B. |
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Afiliação: |
Muriel M. L. Pimentel, Laboratorio de Transplante de Gônadas e de Produção de Embriões In Vitro / Universidade Federal Rural do Semi-Árido; Fernanda A. Santos, Laboratorio de Transplante de Gônadas e de Produção de Embriões In Vitro / Universidade Federal Rural do Semi-Árido; Ana C.G. Teixeira, Laboratorio de Transplante de Gônadas e de Produção de Embriões In Vitro / Universidade Federal Rural do Semi-Árido; Roberta G. Izzo, Laboratorio de Transplante de Gônadas e de Produção de Embriões In Vitro / Universidade Federal Rural do Semi-Árido; Mikael A. Lima, Laboratorio de Transplante de Gônadas e de Produção de Embriões In Vitro / Universidade Federal Rural do Semi-Árido; Michelly F. Macedo, Laboratorio de Transplante de Gônadas e de Produção de Embriões In Vitro / Universidade Federal Rural do Semi-Árido; Marcelo B. Bezerra, Laboratorio de Transplante de Gônadas e de Produção de Embriões In Vitro / Universidade Federal Rural do Semi-Árido. |
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Título: |
Biochemical, thermographic, and follicular responses of murine models of hormone-treated bovine ovarian renal capsule xenografts. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 5, p. 425-431, maio 2017. |
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Idioma: |
Português |
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Notas: |
Título em português: Respostas bioquímicas, termográficas e foliculares de modelos murinos tratados hormonalmente após xenotransplante de ovário bovino sob a cápsula renal. |
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Conteúdo: |
This study aimed to evaluate the characteristics of two different murine models of hormone treated renal-encapsulated bovine ovarian tissue xenotransplantation. Two immunodeficient mouse models (BALB/c Nude and C57BL6 SCID) were xenografted with ovarian pieces from heifers and each group was subjected to two hormonal treatments of eCG or a combination of FSH+LH. Donor ovaries and recipients were evaluated by histology and infrared thermography at different times. At the time of xenograft collection, animals were evaluated for alterations in hepatorenal biochemistry. The statistical test used in the study was ANOVA, followed by Tukey?s test. Among the strains, 80% of C57BL6 SCID and 77% of BALB/c Nude mice showed development and vascularization of the transplanted tissue, which acquired cyclicity at 19 and 9 days post-transplant, respectively. Hemorrhagic follicles in xenografts induced with FSH+LH were found in the C57BL6 SCID strain. Infrared thermography was insufficient to distinguish the tissue donor recipient. In conclusion, the C57BL6 SCID strain appears to be the best host for ovarian xenografts, since the transplants in these mice were viable and showed robust follicular development. This work will aid future choices of immunodeficient strains for xenografting procedures. |
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Palavras-Chave: |
Ovary. |
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Thesagro: |
Camundongo; Novilho; Ovário. |
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Thesaurus NAL: |
Heifers; Mice; Xenotransplantation. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/163103/1/Biochemical-thermographic.pdf
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Marc: |
LEADER 02323naa a2200289 a 4500
001 2074564
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aPIMENTEL, M. M. L.
245 $aBiochemical, thermographic, and follicular responses of murine models of hormone-treated bovine ovarian renal capsule xenografts.$h[electronic resource]
260 $c2017
500 $aTítulo em português: Respostas bioquímicas, termográficas e foliculares de modelos murinos tratados hormonalmente após xenotransplante de ovário bovino sob a cápsula renal.
520 $aThis study aimed to evaluate the characteristics of two different murine models of hormone treated renal-encapsulated bovine ovarian tissue xenotransplantation. Two immunodeficient mouse models (BALB/c Nude and C57BL6 SCID) were xenografted with ovarian pieces from heifers and each group was subjected to two hormonal treatments of eCG or a combination of FSH+LH. Donor ovaries and recipients were evaluated by histology and infrared thermography at different times. At the time of xenograft collection, animals were evaluated for alterations in hepatorenal biochemistry. The statistical test used in the study was ANOVA, followed by Tukey?s test. Among the strains, 80% of C57BL6 SCID and 77% of BALB/c Nude mice showed development and vascularization of the transplanted tissue, which acquired cyclicity at 19 and 9 days post-transplant, respectively. Hemorrhagic follicles in xenografts induced with FSH+LH were found in the C57BL6 SCID strain. Infrared thermography was insufficient to distinguish the tissue donor recipient. In conclusion, the C57BL6 SCID strain appears to be the best host for ovarian xenografts, since the transplants in these mice were viable and showed robust follicular development. This work will aid future choices of immunodeficient strains for xenografting procedures.
650 $aHeifers
650 $aMice
650 $aXenotransplantation
650 $aCamundongo
650 $aNovilho
650 $aOvário
653 $aOvary
700 1 $aSANTOS, F. A.
700 1 $aTEIXEIRA, A. C. G.
700 1 $aIZZO, R. G.
700 1 $aLIMA, M. A.
700 1 $aMACEDFO, M. F.
700 1 $aBEZERRA, M. B.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 5, p. 425-431, maio 2017.
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