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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
21/11/2012 |
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Data da última atualização: |
14/04/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LEPESANT, J. M. J.; COSSEAU, C.; BOISSIER, J.; FREITAG, M.; PORTELA, J.; CLIMENT, D.; PERRIN, C.; ZERLOTINI, A.; GRUNAU, C. |
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Afiliação: |
JULIE M. J. LEPESANT, Université de Perpignan Via Domitia; CÉLINE COSSEAU, Université de Perpignan Via Domitia; JÉROME BOISSIER, Université de Perpignan Via Domitia; MICHAEL FREITAG, Oregon State University; JULIEN PORTELA, Université de Perpignan Via Domitia; DÉBORAH CLIMENT, Université de Perpignan Via Domitia; CÉCILE PERRIN, Université de Perpignan Via Domitia; ADHEMAR ZERLOTINI NETO, CNPTIA; CHRISTOPH GRUNAU, Université de Perpignan Via Domitia. |
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Título: |
Chromatin structural changes around satellite repeats on the female sex chromosome in Schistosoma mansoni and their possible role in sex chromosome emergence. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Genome Biology, v. 13, 2012. |
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Páginas: |
15 p. |
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DOI: |
10.1186/gb-2012-13-2-r14 |
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Idioma: |
Inglês |
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Conteúdo: |
Background: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower estimate for the repeat content is 40%, with an unknown proportion of domesticated repeats. We used massive sequencing to de novo assemble all repeats, and identify unambiguously Z-specific, W-specific and pseudoautosomal regions of the S. mansoni sex chromosomes. Results: We show that 70 to 90% of S. mansoni W and Z are pseudoautosomal. No female-specific gene could be identified. Instead, the W-specific region is composed almost entirely of 36 satellite repeat families, of which 33 were previously unknown. Transcription and chromatin status of female-specific repeats are stage-specific: for those repeats that are transcribed, transcription is restricted to the larval stages lacking sexual dimorphism. In contrast, in the sexually dimorphic adult stage of the life cycle, no transcription occurs. In addition, the euchromatic character of histone modifications around the W-specific repeats decreases during the life cycle. Recombination repression occurs in this region even if homologous sequences are present on both the Z and W chromosomes. Conclusion: Our study provides for the first time evidence for the hypothesis that, at least in organisms with a ZW type of sex chromosomes, repeat-induced chromatin structure changes could indeed be the initial event in sex chromosome emergence. MenosBackground: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower estimate for the repeat content is 40%, with an unknown proportion of domesticated repeats. We used massive sequencing to de novo assemble all repeats, and identify unambiguously Z-specific, W-specific and pseudoautosomal regions of the S. mansoni sex chromosomes. Results: We show that 70 to 90% of S. mansoni W and Z are pseudoautosomal. No female-specific gene could be identified. Instead, the W-specific region is composed almost entirely of 36 satellite repeat families, of which 33 were previously unknown. Transcription and chromatin status of female-specific repeats are stage-specific: for those repeats that are transcribed, transcription is restricted to the larval stages lacking sexual dimorphism. In contrast, in the sexually dimorphic adult stage of the life cycle, no transcription occurs. In addition, the euchromatic character of histone modifications around the W-specific repeats decreases during the life cycle. Recombination repression occurs in this region even if homologous sequences are present on both the Z and W chromosomes. Conclusion: Our study provides for the first time evidence for the hypothesis that, ... Mostrar Tudo |
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Thesaurus Nal: |
Schistosoma. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/70524/1/gb-2012-13-2-r14.pdf
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Marc: |
LEADER 02420naa a2200253 a 4500
001 1940197
005 2020-04-14
008 2012 bl uuuu u00u1 u #d
024 7 $a10.1186/gb-2012-13-2-r14$2DOI
100 1 $aLEPESANT, J. M. J.
245 $aChromatin structural changes around satellite repeats on the female sex chromosome in Schistosoma mansoni and their possible role in sex chromosome emergence.$h[electronic resource]
260 $c2012
300 $a15 p.
520 $aBackground: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower estimate for the repeat content is 40%, with an unknown proportion of domesticated repeats. We used massive sequencing to de novo assemble all repeats, and identify unambiguously Z-specific, W-specific and pseudoautosomal regions of the S. mansoni sex chromosomes. Results: We show that 70 to 90% of S. mansoni W and Z are pseudoautosomal. No female-specific gene could be identified. Instead, the W-specific region is composed almost entirely of 36 satellite repeat families, of which 33 were previously unknown. Transcription and chromatin status of female-specific repeats are stage-specific: for those repeats that are transcribed, transcription is restricted to the larval stages lacking sexual dimorphism. In contrast, in the sexually dimorphic adult stage of the life cycle, no transcription occurs. In addition, the euchromatic character of histone modifications around the W-specific repeats decreases during the life cycle. Recombination repression occurs in this region even if homologous sequences are present on both the Z and W chromosomes. Conclusion: Our study provides for the first time evidence for the hypothesis that, at least in organisms with a ZW type of sex chromosomes, repeat-induced chromatin structure changes could indeed be the initial event in sex chromosome emergence.
650 $aSchistosoma
700 1 $aCOSSEAU, C.
700 1 $aBOISSIER, J.
700 1 $aFREITAG, M.
700 1 $aPORTELA, J.
700 1 $aCLIMENT, D.
700 1 $aPERRIN, C.
700 1 $aZERLOTINI, A.
700 1 $aGRUNAU, C.
773 $tGenome Biology$gv. 13, 2012.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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| Registros recuperados : 11 | |
| 5. |  | SOARES, E. A. C.; ARAUJO, J. de M.; GOMES, E. A.; SILVA, P. G.; MATTOS, B. B.; ALVES, V. M. C.; MARRIEL, I. E.; OLIVEIRA-PAIVA, C. A. Alterações na atividade das enzimas fosfatases ácidas e alcalinas, em solo cultivado com milheto adubado com fosfatos e inoculado com microrganismos solubilizadores. In: CONGRESSO NACIONAL DE MILHO E SORGO, 29., 2012, Águas de Lindóia. Diversidade e inovações na era dos transgênicos: resumos expandidos. Campinas: Instituto Agronômico; Sete Lagoas: Associação Brasileira de Milho e Sorgo, 2012. p. 1770-1777. 1 CD-ROM.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 6. | | BELTRÃO, N. E. de M.; AZEVEDO, D. M. P. de; NOBREGA, L. B. da; VIEIRA, D. J.; DANTAS, E. S. B.; ALVES, I.; ARAUJO, J. de. Crescimento, produtividade e qualidade de fibra da cultivar 7MH no Serido da Paraiba, em condicoes de baixa pluviosidade: dados de 1997. Campina Grande: EMBRAPA-CNPA, 1997. 4p. (EMBRAPA-CNPA. Pesquisa em Andamento, 73)| Biblioteca(s): Embrapa Algodão. |
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| 7. | | ARAÚJO, A. C. de; BELTRÃO, N. E. de M.; MORAIS, M. dos S.; ARAÚJO, J. de L. O.; CUNHA, J. L. X. L.; PAIXÃO, S. L. Indicadores agroeconômicos na avaliação do consórcio algodão herbáceo + amendoim. Ciência e agrotecnologia, v. 32, n. 5, p. 1467-1472, set./out.,2008| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Nacional - A |
| Biblioteca(s): Embrapa Algodão. |
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| 8. | | COSTA, J. J. O. da; FRADE JÚNIOR, E. F.; PEREIRA, M. G.; COSTA, F. de S.; MENEZES, A. L. de; SILVA, S. B. da; ARAUJO, J, de A.; ARAÚJO, J. da C. Características físicas em sistemas agrícolas da Amazônia Ocidental - Acre. In: CONGRESSO BRASILEIRO DE CIÊNCIA DO SOLO, 33., 2011, Uberlândia. Solos nos biomas brasileiros: sustentabilidade e mudanças climáticas: anais. Uberlândia: SBCS, 2011. 4 p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Acre. |
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| 9. | | DIAS, N. da S.; MELO, D. S.; ARAÚJO, J. de L.; MACIEL, G. P. de S.; GOMES, FILHO, A. A. H.; SANTOS, E. S. dos; BRAGA, C. A. T. Respostas preliminares de progênies de cajueiro-anão à infestação da broca-das-pontas e da traça-da-castanha. Fortaleza: Embrapa Agroindústria Tropical, 2018. 13 p. (Embrapa Agroindústria Tropical. Boletim de pesquisa e desenvolvimento, 156).| Tipo: Boletim de Pesquisa e Desenvolvimento |
| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 11. | | SANTOS, T. B.; ARA[UJO, F. P. de; NETO, A. F.; FREITAS, S. T. de; ARAÚJO, J. de S; VILAR, S. B. de O.; ARAÚJO, A. J. B.; LIMA, M. S. Phytochemical compounds and antioxidant activity of the pulp of two brazilian passion fruit species: Passiflora cincinnata Mast. And Passiflora edulis Sims. International Journal of Fruit Science, v. 21, n. 1, p. 255-269, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 5 |
| Biblioteca(s): Embrapa Semiárido. |
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| Registros recuperados : 11 | |
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