Data/hora: 15/06/2024 15:33:09

Biblioteca(s): | Embrapa Instrumentação; Embrapa Suínos e Aves.
Data corrente: | 05/10/2020
Data da última atualização: | 05/10/2020
Autoria: | COLNAGO, L. A.; TREVISOL, I. M.; VOSS RECH, D.; FORATO, L. A.; MITRE, C. I. N.; LEITE, J. P. G.; GIGLIOTI, R.; OKINO, C. H.
Afiliação: | LUIZ ALBERTO COLNAGO, CNPDIA; IARA MARIA TREVISOL, CNPSA; LUCIMARA APARECIDA FORATO, CNPDIA; CINTIA HIROMI OKINO, CPPSE.
Título: | Simple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge.
Ano de publicação: | 2020
Fonte/Imprenta: | International Journal of Environmental Research and Public Health, v. 17, a. 6456, 2020.
Páginas: | 1 - 9
DOI: | 10.3390/ijerph17186456
Idioma: | Inglês

Conteúdo:

Abstract: The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal
among populations with lower socioeconomic status. Direct contact with contaminated surfaces has
been among the virus sources, as it remains infective up to days. Several disinfectants have been
shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be
scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare,
low-cost and effcient antiviral films, made with a widely available dishwashing detergent, which can
be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer
periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to
test the antivirus effcacy of the proposed films. Polystyrene petri dishes were covered with a thin
layer of detergent formula. After drying, the films were exposed to different virus doses for 10 min
and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification
in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50),
which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent
alternative to minimize the spread of COVID-19.

Palavras-Chave: | Antiviral; Coronavirus; COVID-19; Detergent; Film; Sanitization; SARS-CoV-2; Virucide.
Thesagro: | Aviário; Virologia.
Categoria do assunto: | --
Registro original: | Embrapa Instrumentação (CNPDIA)

Exemplares:

CNPDIA - (17596-1) - UPC - AP - DD - PROCI.20/078 -  - 2020/0086 - DIS
CNPSA - (21985-1) - UPC - AP - DD -  -  -  - DIS