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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
14/02/1996 |
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Data da última atualização: |
14/02/1996 |
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Autoria: |
LEE, T. D. G.; SWIETER, M.; BEFUS, A. D. |
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Afiliação: |
Department of Microbioloogy and Infectious Diseases Faculty of Medicine. University of Calgary, Alberta, Canada. |
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Título: |
Mast cell responses to Helminth infection |
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Ano de publicação: |
1986 |
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Fonte/Imprenta: |
Parasitology Today, v.2, n.7, p.1-6, July, 1986. |
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Idioma: |
Inglês |
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Conteúdo: |
Mast cell have been suggested to be major effector cells in the immune response to infection with helminths. It is now clear, however, that mast cells are heterogeneous and have a diversity of important functions. In this review, Timothy Lee, Mark Swieter and Dean Befus point out that much of the consusion about the role of mast cells in immunity stems from methods and interpretations which are inadequate for the diversity of roles played by these cells in host responses to parasites. Classical histochemistry may fail to reveal active mast cells, and studies using chemical antagonists are difficult to interpret until we know more about the action of the drugs. The authors show that current research is extending our knowledge of mat cell heterogeneity, and helping to define the powerful array of mediators that they can use to orchestrate the immune response to helminth infections. |
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Palavras-Chave: |
Helminth infection; Mast cell; Parasita; Parasite. |
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Thesagro: |
Helminto; Infecção. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01425naa a2200217 a 4500
001 1787311
005 1996-02-14
008 1986 bl --- 0-- u #d
100 1 $aLEE, T. D. G.
245 $aMast cell responses to Helminth infection
260 $c1986
520 $aMast cell have been suggested to be major effector cells in the immune response to infection with helminths. It is now clear, however, that mast cells are heterogeneous and have a diversity of important functions. In this review, Timothy Lee, Mark Swieter and Dean Befus point out that much of the consusion about the role of mast cells in immunity stems from methods and interpretations which are inadequate for the diversity of roles played by these cells in host responses to parasites. Classical histochemistry may fail to reveal active mast cells, and studies using chemical antagonists are difficult to interpret until we know more about the action of the drugs. The authors show that current research is extending our knowledge of mat cell heterogeneity, and helping to define the powerful array of mediators that they can use to orchestrate the immune response to helminth infections.
650 $aHelminto
650 $aInfecção
653 $aHelminth infection
653 $aMast cell
653 $aParasita
653 $aParasite
700 1 $aSWIETER, M.
700 1 $aBEFUS, A. D.
773 $tParasitology Today$gv.2, n.7, p.1-6, July, 1986.
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Registro original: |
Embrapa Pantanal (CPAP) |
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