Data/hora: 21/06/2024 03:52:56

Biblioteca(s): | Embrapa Caprinos e Ovinos.
Data corrente: | 12/09/1996
Data da última atualização: | 12/09/1996
Autoria: | LANUSSE, C. E.; PRICHARD, R. K.
Título: | Relationship between pharmacological properties and clinical efficacy of ruminant anthelmintics.
Ano de publicação: | 1993
Fonte/Imprenta: | Veterinary Parasitology, v.49, n.2-4, p.123-158, 1993.
Idioma: | Inglês
Conteúdo: | The purpose of this review article is to establish a relationship between pharmacological properties and clinical efficacy of the most widely used broad-spectrum veterinary anthelmintics. The impact of drug  pharmacokinetics/pharmacodynamics on anthelmintic efficacy and resistance is discussed. We review the clinical pharmacokinetics of the currently available anthelmintics used in livestock-imidazothiazoles, tetrahydropyrimidines, benzimidazoles/pro-benzimidazoles, salicylanilides (closantel) and a avermectin-type compounds. Understanding the pharmacokinetic and metabolic behaviour of broad-spectrum anthelmintics in the host, and factors modulating that behaviour, is highly iimportant for maximizing anthelmintic utility and efficacy.
Palavras-Chave: | Anthelmintic control; Controle antihelmintico; Ruminant.
Thesagro: | Parasitologia; Ruminante.
Thesaurus Nal: | parasitology.
Categoria do assunto: | --
Registro original: | Embrapa Caprinos e Ovinos (CNPC)
Exemplares: | CNPC - (3372-1) - ADC - AP - -- -  -  - 1996.00000 - DIS