Data/hora: 01/06/2024 02:44:34

Biblioteca(s): | Embrapa Amazônia Oriental.
Data corrente: | 17/11/2016
Data da última atualização: | 23/05/2022
Autoria: | GOBO, L. A.; VIANA, C.; LAMEIRA, O. A.; CARVALHO, L. M. de.
Afiliação: | Luciana Assis Gobo, UFSM; Carine Viana, GRADUANDA UFSM; OSMAR ALVES LAMEIRA, CPATU; Leandro Machado de Carvalho, UFSM.
Título: | A liquid chromatography-atmospheric pressure photoionization tandem mass spectrometric (LC-APPI-MS/MS) method for the determination of triterpenoids in medicinal plant extracts.
Ano de publicação: | 2016
Fonte/Imprenta: | Journal of Mass Spectrometry, v. 51, n. 8, p. 558-565, Aug. 2016.
DOI: | 10.1002/jms.3783
Idioma: | Inglês
Conteúdo: | An analytical method using liquid chromatography-atmospheric pressure photoionization tandem mass spectrometry with toluene as a dopant was developed for the determination of triterpenes in medicinal plant extracts. The 12 compounds determined have been shown to exhibit biological activity, such as gastroprotective, hepatoprotective, anti-inflammatory, antiviral and anti-tumor effects. The parameters of the atmospheric pressure photoionization interface were optimized to obtain the highest possible sensitivity for all of the compounds. The limits of detection and quantification ranged from 0.4 to 157.9 and 1.3 to 526.4, respectively. The method was validated and applied to extracts of five medicinal plants species (Mansoa alliacea (Lam.) A.H.Gentry, Bauhinia variegata var variegata, Bauhinia variegata var alboflava, Cecropia obtuse Trécul and Cecropia palmate Willd) from the Amazonian region. The concentrations of the six triterpenes quantified in the samples ranged from for ursolic acid to amyrin, which were quantified by using the standard addition method
Palavras-Chave: | Validação.
Thesagro: | Extrato; Planta Medicinal.
Thesaurus Nal: | Amazonia.
Categoria do assunto: | F Plantas e Produtos de Origem Vegetal
Registro original: | Embrapa Amazônia Oriental (CPATU)
Exemplares: | CPATU - (52916-1) - UPC - AP - DD -  -  -  - DIS