Data/hora: 02/06/2024 12:45:48

Biblioteca(s): 	Embrapa Caprinos e Ovinos.	
Data corrente: 	14/12/1995	
Data da última atualização: 	14/12/1995	
Autoria: 	BAUMIK, A.; SHARMA, M. C.; LAL, S. B.	
Título: 	Clinico-pathological studies in paracetamol-induced hepatopathy in sheep.	
Ano de publicação: 	1995	
Fonte/Imprenta: 	Indian Journal of Animal Science, v.65, n.2, p.183-185, 1995.	
Idioma: 	Inglês	
Conteúdo: 	The present experiment was undertaken to study the clinico-pathological changes in sheep after paracetamol-induced hepatopathY. Twelve adult, healthy crossbred sheep (Dorset x Muzaffarnagari and Suffolk x Muzaffarnagari) of either sex and maintained on standard/feeding/managemental condition for 6 weeks were taken up for the present study. These animaIs were dewormed and given antibiotic coverage, and were randomly divided into 2 equal groups (groups 1 and 2) of 6 animaIs each. To induce hepatopathy 2 paracetamol was administered @ 400 mg/kg body weight by single intravenous injection to animaIs of group 2. Group 1 animaIs served as healthy control. From the present study it was concluded that paracetamol @ 400 mg/kg body weight can be used to induce hepatopathy in sheep. A significant decrease in blood glucose, total serum proteins, albumin, A:G ratio and total cholesterol with a significant increase in total serum bilirubin, serum AST, ALT levels and BSP% retention was recordedin liver-damaged goats than in controI group. Histopathologically liver revealed necrotic changes and foamy appearance of hepatocytes along with leucocytic infiltration.	
Thesagro: 	Doença; Fígado; Ovino.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPC - (2629-1) - ADC - AP - -- -  -  - 1995.00000 - DIS