Data/hora: 16/06/2024 04:12:22

Biblioteca(s): 	Embrapa Meio Ambiente.	
Data corrente: 	06/11/2018	
Data da última atualização: 	06/11/2018	
Autoria: 	SILVA, G. H. da; CLEMENTE, Z.; KHAN, L. U.; COA, F.; RODRIGUES NETO, L. L.; CARVALHO, H. W. P. de; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T.; MONTEIRO, R. T. R.	
Afiliação: 	GABRIELA HELENA DA SILVA, CENA-USP; ZAIRA CLEMENTE, CNPEM; LATIF ULLAH KHAN, CNPEM; FRANCINE COA, CENA-SUP; LAIS LUZ RODRIGUES NETO, CNPEM; HUDSON WALLACE PEREIRA DE CARVALHO, CENA-USP; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; DIEGO STEFANI TEODORO MARTINEZ, CENA-USP; REGINA TERESA ROSIM MONTEIRO, CENA-USP.	
Título: 	Toxicity assessment of TiO2-MWCNT nanohybrid material with enhanced photocatalytic activity on Danio rerio (Zebrafish) embryos.	
Ano de publicação: 	2018	
Fonte/Imprenta: 	Ecotoxicology and Environmental Safety, v. 165, p. 136-143, 2018.	
ISSN: 	0147-6513	
DOI: 	https://doi.org/10.1016/j.ecoenv.2018.08.093	
Idioma: 	Inglês	
Conteúdo: 	Abstract: The increasing production and use of nanomaterials is causing serious concerns about their safety to human and environmental health. However, the applications of titanium dioxide nanoparticles (TiO2NP) and multiwalled carbon nanotubes (MWCNT) hybrids has grown considerably, due to their enhanced photocatalytic efficiency. To our knowledge, there are no reports available to the scientific community about their toxicity. In this work, we perform a toxicity assessment of TiO2NP and TiO2-MWCNT nanohybrid materials using Zebrafish embryos standardized 96?h early life stage assay, under different exposure conditions (with and without UV light exposure). After exposure the parameters assessed were acute toxicity, hatching rate, growth, yolk sac size, and sarcomere length. In addition, ?-probe X-ray fluorescence spectroscopy (µ-XRF) was employed to observe if nanoparticles were uptaken by zebrafish embryos and consequently accumulated in their organisms. Neither TiO2NP nor TiO2-MWCNT nanohybrids presented acute toxicity to the zebrafish embryos. Moreover, TiO2NP presents sublethal effects for total length (with and without UV light exposure) on the embryos. This work contributes to the understanding of the potential adverse effects of the emerging nanohybrid materials towards safe innovation approaches in nanotechnology.	
Palavras-Chave: 	Nanocompostos; Nanohybrids; Nanotoxicity; Nanotubos; TiO2.	
Thesagro: 	Composto Químico; Impacto Ambiental; Peixe de Água Doce; Toxidez.	
Thesaurus Nal: 	Carbon nanotubes; Danio rerio; Ecotoxicology; Nanocomposites.	
Categoria do assunto: 	H Saúde e Patologia	
Registro original: 	Embrapa Meio Ambiente (CNPMA)	
Exemplares: 	CNPMA - (16191-1) - UPC - AP - DD -  -  -  - DIS