Data/hora: 16/06/2024 17:32:57

Biblioteca(s): | Embrapa Caprinos e Ovinos.
Data corrente: | 11/09/2018
Data da última atualização: | 11/09/2018
Autoria: | MCHARDY, N.; WOOLLON, R. M.; CLAMPITT, R. B.; JAMES, J. A.; CRAWLEY, R. J.
Título: | Efficacy, toxicity and metabolism of imidocarb dipropionate in the treatment of Babesia ovis infection in sheep.
Ano de publicação: | 1986
Fonte/Imprenta: | Research in Veterinary Science, v. 41, n. 1, p. 14-20, Jul. 1986.
Idioma: | Inglês
Conteúdo: | Abstract: An intramuscular dose of 1.2 mg kg-1 of imidocarb dipropionate (IMDP) was effective in controlling fatal infections with Babesia ovis in sheep. The sheep were infected by the intravenous injection of sheep blood containing B ovis. A severe recrudescence of infection occurred in most sheep 10 to 14 days after therapy but this could be controlled by a second dose of 1.2 mg kg-1 IMDP. Studies on the toxicology, residues and metabolism of IMDP showed this to be a safe dosage regimen. Transient or mild signs of toxicity were seen at 2.4 and 4.8 mg kg-1 IMDP. Severe toxicity was observed in sheep treated with 9.6 mg kg-1.
Palavras-Chave: | Imidocarb dipropionate.
Thesaurus Nal: | Babesiosis; Blood; Creatinine; Drug evaluation; Drug therapy; Imidocarb; Magnesium; Parasitology; Sheep diseases; Urea.
Categoria do assunto: | H Saúde e Patologia
Registro original: | Embrapa Caprinos e Ovinos (CNPC)
Exemplares: | CNPC - (37627-1) - ADD - AP - PP -  -  -  - DIS