| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
|
Data corrente: |
28/06/2017 |
|
Data da última atualização: |
28/06/2017 |
|
Autoria: |
TAYLOR, M. G.; JAMES, E. R.; BICKLE, Q.; HUSSEIN, M. F.; ANDREWS, B. J.; DOBINSON, A. R.; NELSON, G. S. |
|
Título: |
Immunization of sheep against Schistosoma bovis using an irradiated schistosomular vaccine. |
|
Ano de publicação: |
1979 |
|
Fonte/Imprenta: |
Journal of Helminthology, v. 53, n. 1, p. 1-5, Mar. 1979. |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract: S. bovis is an economically important parasite of cattle and possibly of sheep and other domestic stock in many African and Mediterranean countries. Control of this infection by chemotherapy and mollusciciding is impractical and this has stimulated interest in vaccination. Previous work in sheep with the Central and South African species S. mattheei has led to the development of an effective vaccine which incorporates irradiated schistosomula produced by artificial transformation of cercariae. In the present experiments a similar S. bovis vaccine has been used in sheep. Fifteen 5 month old Border Leicester × Suffolk crossbred wethers were divided into three groups, two were vaccinated with either 10000 or 20000 6 krad irradiated S. bovis schistosomula, and the third kept as unvaccinated controls. All sheep were challenged with 6700 normal S. bovis cercariae. Worm recoveries and tissue egg counts at necropsy showed that vaccination with 10000 irradiated schistosomula produced a reduction of 71% in the mean worm burden resulting from challenge of the controls and the mean densities of eggs in the tissues were reduced by 75?82%. Immunization with 20000 irradiated schistosomula was not more effective. Histopathological observations showed that both groups of vaccinated sheep had much milder lesions in the intestines than the non-vaccinated controls. There was also a clear reduction in the severity of liver lesions in 4 of the 5 sheep given the lower dose of irradiated schistosomula but the livers of sheep vaccinated with 20000 irradiated schistosomula had severe and widespread lesions due mainly to a massive accumulation of eosinophils and other inflammatory cells around the vessels. MenosAbstract: S. bovis is an economically important parasite of cattle and possibly of sheep and other domestic stock in many African and Mediterranean countries. Control of this infection by chemotherapy and mollusciciding is impractical and this has stimulated interest in vaccination. Previous work in sheep with the Central and South African species S. mattheei has led to the development of an effective vaccine which incorporates irradiated schistosomula produced by artificial transformation of cercariae. In the present experiments a similar S. bovis vaccine has been used in sheep. Fifteen 5 month old Border Leicester × Suffolk crossbred wethers were divided into three groups, two were vaccinated with either 10000 or 20000 6 krad irradiated S. bovis schistosomula, and the third kept as unvaccinated controls. All sheep were challenged with 6700 normal S. bovis cercariae. Worm recoveries and tissue egg counts at necropsy showed that vaccination with 10000 irradiated schistosomula produced a reduction of 71% in the mean worm burden resulting from challenge of the controls and the mean densities of eggs in the tissues were reduced by 75?82%. Immunization with 20000 irradiated schistosomula was not more effective. Histopathological observations showed that both groups of vaccinated sheep had much milder lesions in the intestines than the non-vaccinated controls. There was also a clear reduction in the severity of liver lesions in 4 of the 5 sheep given the lower dose of irradiated ... Mostrar Tudo |
|
Palavras-Chave: |
Pathology. |
|
Thesaurus Nal: |
Animal diseases; Disease control; Disease prevention; Immunology; Schistosoma bovis; Sheep; Vaccines. |
|
Categoria do assunto: |
H Saúde e Patologia |
|
Marc: |
LEADER 02504naa a2200289 a 4500
001 2071608
005 2017-06-28
008 1979 bl uuuu u00u1 u #d
100 1 $aTAYLOR, M. G.
245 $aImmunization of sheep against Schistosoma bovis using an irradiated schistosomular vaccine.
260 $c1979
520 $aAbstract: S. bovis is an economically important parasite of cattle and possibly of sheep and other domestic stock in many African and Mediterranean countries. Control of this infection by chemotherapy and mollusciciding is impractical and this has stimulated interest in vaccination. Previous work in sheep with the Central and South African species S. mattheei has led to the development of an effective vaccine which incorporates irradiated schistosomula produced by artificial transformation of cercariae. In the present experiments a similar S. bovis vaccine has been used in sheep. Fifteen 5 month old Border Leicester × Suffolk crossbred wethers were divided into three groups, two were vaccinated with either 10000 or 20000 6 krad irradiated S. bovis schistosomula, and the third kept as unvaccinated controls. All sheep were challenged with 6700 normal S. bovis cercariae. Worm recoveries and tissue egg counts at necropsy showed that vaccination with 10000 irradiated schistosomula produced a reduction of 71% in the mean worm burden resulting from challenge of the controls and the mean densities of eggs in the tissues were reduced by 75?82%. Immunization with 20000 irradiated schistosomula was not more effective. Histopathological observations showed that both groups of vaccinated sheep had much milder lesions in the intestines than the non-vaccinated controls. There was also a clear reduction in the severity of liver lesions in 4 of the 5 sheep given the lower dose of irradiated schistosomula but the livers of sheep vaccinated with 20000 irradiated schistosomula had severe and widespread lesions due mainly to a massive accumulation of eosinophils and other inflammatory cells around the vessels.
650 $aAnimal diseases
650 $aDisease control
650 $aDisease prevention
650 $aImmunology
650 $aSchistosoma bovis
650 $aSheep
650 $aVaccines
653 $aPathology
700 1 $aJAMES, E. R.
700 1 $aBICKLE, Q.
700 1 $aHUSSEIN, M. F.
700 1 $aANDREWS, B. J.
700 1 $aDOBINSON, A. R.
700 1 $aNELSON, G. S.
773 $tJournal of Helminthology$gv. 53, n. 1, p. 1-5, Mar. 1979.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
Registro Completo
|
Biblioteca(s): |
Embrapa Gado de Leite. |
|
Data corrente: |
31/03/2009 |
|
Data da última atualização: |
28/06/2023 |
|
Tipo da produção científica: |
Capítulo em Livro Técnico-Científico |
|
Autoria: |
OLIVEIRA, L. F. de; BELKE, V. L.; MITTELMANN, A.; BRANDOLI, M. A. A. |
|
Afiliação: |
Luiz Flávio de Oliveira, COOPATRIGO; Vilson Lauri Belke Escola Técnica Estadual Cruzeiro do Sul São Luiz Gonzaga RS; Andréa Mittelmann, Embrapa Gado de Leite; Marcelo Antônio Araldi Brandoli, EMATER/RS. |
|
Título: |
A alfafa no Rio Grande do Sul. |
|
Ano de publicação: |
2008 |
|
Fonte/Imprenta: |
In: MITTELMANN, A.; LÉDO, F. J. da S.; GOMES, J. F. (ed.). Tecnologias para a produção de alfafa no Rio Grande do Sul. Pelotas: Embrapa Clima Temperado; Juiz de Fora: Embrapa Gado de Leite, 2008. |
|
Páginas: |
p. 11-16. |
|
Idioma: |
Português |
|
Palavras-Chave: |
Cultivo. |
|
Thesagro: |
Alfafa. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/596673/1/A-alfafa-no-Rio-Grande-do-Sul.pdf
|
|
Marc: |
LEADER 00631naa a2200181 a 4500
001 1596673
005 2023-06-28
008 2008 bl uuuu u00u1 u #d
100 1 $aOLIVEIRA, L. F. de
245 $aA alfafa no Rio Grande do Sul.$h[electronic resource]
260 $c2008
300 $ap. 11-16.
650 $aAlfafa
653 $aCultivo
700 1 $aBELKE, V. L.
700 1 $aMITTELMANN, A.
700 1 $aBRANDOLI, M. A. A.
773 $tIn: MITTELMANN, A.; LÉDO, F. J. da S.; GOMES, J. F. (ed.). Tecnologias para a produção de alfafa no Rio Grande do Sul. Pelotas: Embrapa Clima Temperado; Juiz de Fora: Embrapa Gado de Leite, 2008.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Expressão de busca inválida. Verifique!!! |
|
|
