Data/hora: 17/06/2024 00:31:45

Biblioteca(s): 	Embrapa Caprinos e Ovinos.	
Data corrente: 	11/12/1997	
Data da última atualização: 	03/10/2016	
Autoria: 	PERSON-WALLER, K.; COLDITZ, I. G.; SEOW, H. F.	
Título: 	Accumulation of leucocytes and cytokines in the lactating ovine udder during mastitis due to Staphylococcus aureus and Escherichia coli.	
Ano de publicação: 	1997	
Fonte/Imprenta: 	Research in Veterinary Science, v. 62, n. 1, p. 63-66, 1997.	
Idioma: 	Inglês	
Conteúdo: 	Abstract: The accumulation of leucocytes in milk and in teat cistern tissues, and the presence of the cytokines interleukin-1 beta (IL-1 beta), tumour necrosis factor-alpha (TNF-alpha), interleukin-8 (IL-8), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interferon-gamma (IFN-gamma) in milk was studied during inflammation in the lactating ovine udder induced by Staphylococcus aureus and Escherichia coli. Milk and/or teat tissue samples were taken before and four, eight and 24 hours after inoculation. Both S aureus and E coli induced a significant accumulation of leucocytes in milk, S aureus from eight hours with a peak after 24 hours, and E coli from four hours, with a peak after eight hours. After the inoculation of S aureus the numbers of subepithelial neutrophils in the teat cistern tissues were increased after four hours and had increased further by eight hours. After the inoculation of E coli, tissue neutrophil numbers peaked at four hours and were still high at eight hours. Large numbers of S aureus were recovered from milk throughout the experiments whereas the recovery of E coli diminished over time. TNF-alpha, IL-8 and IL-1 beta were detected in milk during the inflammation, and low levels of GM-CSF and IFN-gamma were also observed occasionally. Of the cytokines measured, TNF-alpha and IL-8 reached the highest concentrations, accumulating in a similar pattern to the leucocytes for both infections. IL-1 beta was detected mainly during S aureus-induced inflammation, indicating differences in the inflammatory responses elicited by the organisms.	
Palavras-Chave: 	Mastite.	
Thesagro: 	Ovino.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPC - (3984-1) - ADD - AP - -- -  -  - 1997.00000 - DIS