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Registro Completo
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
06/12/2016 |
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Data da última atualização: |
06/12/2016 |
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Autoria: |
PEREIRA, G. G.; GOLDFEDER, G. T.; YAMAKI, F. L.; OLIVEIRA, V. M. C.; LARSSON, M. H. M. A. |
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Afiliação: |
GUILHERME G. PEREIRA, FMVZ/USP; GUILHERME T. GOLDFEDER, FMVZ/USP; FERNANDA L. YAMAKI, FMVZ/USP; VALÉRIA M. C. OLIVEIRA, FMVZ/USP; MARIA HELENA M. A. LARSSON, FMVZ/USP. |
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Título: |
Myocardial velocities obtained by pulsed tissue Doppler in English Cocker Spaniels with dilated cardiomyopathy and congestive heart failure. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Brasília, DF, v. 39, n. 9, p. 851-856, set. 2016. |
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Idioma: |
Inglês |
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Conteúdo: |
Dilated cardiomyopathy (DCM) is characterized by systolic myocardial dysfunction which is identified by low myocardial velocities obtained by pulsed tissue Doppler (PTD). However, increased preload is known to increase myocardial velocities which could overestimate myocardial function and turn dysfunction characterization into a challenge in dogs with DCM and congestive heart failure. To test the hypothesis that increased preload could hamper identification of low myocardial velocities in dogs with DCM and congestive heart failure the present study prospectively evaluated 32 English Cocker Spaniel dogs, being 16 with clinical DCM and 16 healthy for control purpose. The PTD analysis of regional velocities were performed in both longitudinal and radial myocardial displacements and systolic (Sm), early (Em) and late diastolic (Am) velocities were obtained in left ventricular free wall (LVFW) and interventricular septum (IVS). Peak radial subendocardial and subepicardial Sm velocities were lower in DCM group compared to control (0.065±0.018 vs. 0.102±0.020m/s and 0.059±0.014 vs. 0.094±0.025m/s respectively; p<0.001). Peak longitudinal Sm velocities were lower in basal and medial portions of LVFW (0.093±0.034 vs. 0.155±0.034m/s and 0.091±0.033 vs 134±0.037m/s respectively; p<0.001) and IVS (0.063±0.021 vs. 0.136±0.039 and 0.066±0.026 vs. 0.104±0.032m/s respectively; p<0.001). Most of diastolic velocities were not significantly different between groups, although advanced myocardial disease and dysfunction are expected in DCM group. Reduction in systolic basal and medial longitudinal myocardial velocities and in radial myocardial velocities was the most significant PTD findings. Increased preload did not represent a problem to evaluate systolic dysfunction by PTD in English Cocker Spaniels with DCM, but influence of preload on assessment of diastolic velocities should be better elucidated. MenosDilated cardiomyopathy (DCM) is characterized by systolic myocardial dysfunction which is identified by low myocardial velocities obtained by pulsed tissue Doppler (PTD). However, increased preload is known to increase myocardial velocities which could overestimate myocardial function and turn dysfunction characterization into a challenge in dogs with DCM and congestive heart failure. To test the hypothesis that increased preload could hamper identification of low myocardial velocities in dogs with DCM and congestive heart failure the present study prospectively evaluated 32 English Cocker Spaniel dogs, being 16 with clinical DCM and 16 healthy for control purpose. The PTD analysis of regional velocities were performed in both longitudinal and radial myocardial displacements and systolic (Sm), early (Em) and late diastolic (Am) velocities were obtained in left ventricular free wall (LVFW) and interventricular septum (IVS). Peak radial subendocardial and subepicardial Sm velocities were lower in DCM group compared to control (0.065±0.018 vs. 0.102±0.020m/s and 0.059±0.014 vs. 0.094±0.025m/s respectively; p<0.001). Peak longitudinal Sm velocities were lower in basal and medial portions of LVFW (0.093±0.034 vs. 0.155±0.034m/s and 0.091±0.033 vs 134±0.037m/s respectively; p<0.001) and IVS (0.063±0.021 vs. 0.136±0.039 and 0.066±0.026 vs. 0.104±0.032m/s respectively; p<0.001). Most of diastolic velocities were not significantly different between groups, although advanced myocardia... Mostrar Tudo |
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Palavras-Chave: |
Cardiomiopatia; Diastolic function; Função diastólica; Função miocárdica; Função sistólica; Myocardial function; Myocardial velocities; Systolic function; Velocidade miocárdica. |
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Thesagro: |
Cão. |
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Thesaurus NAL: |
Cardiomyopathy; Dogs; Heart failure. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/151269/1/Myocardial-velocities-obtained.pdf
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Marc: |
LEADER 02943naa a2200325 a 4500
001 2057980
005 2016-12-06
008 2016 bl uuuu u00u1 u #d
100 1 $aPEREIRA, G. G.
245 $aMyocardial velocities obtained by pulsed tissue Doppler in English Cocker Spaniels with dilated cardiomyopathy and congestive heart failure.
260 $c2016
520 $aDilated cardiomyopathy (DCM) is characterized by systolic myocardial dysfunction which is identified by low myocardial velocities obtained by pulsed tissue Doppler (PTD). However, increased preload is known to increase myocardial velocities which could overestimate myocardial function and turn dysfunction characterization into a challenge in dogs with DCM and congestive heart failure. To test the hypothesis that increased preload could hamper identification of low myocardial velocities in dogs with DCM and congestive heart failure the present study prospectively evaluated 32 English Cocker Spaniel dogs, being 16 with clinical DCM and 16 healthy for control purpose. The PTD analysis of regional velocities were performed in both longitudinal and radial myocardial displacements and systolic (Sm), early (Em) and late diastolic (Am) velocities were obtained in left ventricular free wall (LVFW) and interventricular septum (IVS). Peak radial subendocardial and subepicardial Sm velocities were lower in DCM group compared to control (0.065±0.018 vs. 0.102±0.020m/s and 0.059±0.014 vs. 0.094±0.025m/s respectively; p<0.001). Peak longitudinal Sm velocities were lower in basal and medial portions of LVFW (0.093±0.034 vs. 0.155±0.034m/s and 0.091±0.033 vs 134±0.037m/s respectively; p<0.001) and IVS (0.063±0.021 vs. 0.136±0.039 and 0.066±0.026 vs. 0.104±0.032m/s respectively; p<0.001). Most of diastolic velocities were not significantly different between groups, although advanced myocardial disease and dysfunction are expected in DCM group. Reduction in systolic basal and medial longitudinal myocardial velocities and in radial myocardial velocities was the most significant PTD findings. Increased preload did not represent a problem to evaluate systolic dysfunction by PTD in English Cocker Spaniels with DCM, but influence of preload on assessment of diastolic velocities should be better elucidated.
650 $aCardiomyopathy
650 $aDogs
650 $aHeart failure
650 $aCão
653 $aCardiomiopatia
653 $aDiastolic function
653 $aFunção diastólica
653 $aFunção miocárdica
653 $aFunção sistólica
653 $aMyocardial function
653 $aMyocardial velocities
653 $aSystolic function
653 $aVelocidade miocárdica
700 1 $aGOLDFEDER, G. T.
700 1 $aYAMAKI, F. L.
700 1 $aOLIVEIRA, V. M. C.
700 1 $aLARSSON, M. H. M. A.
773 $tPesquisa Veterinária Brasileira, Brasília, DF$gv. 39, n. 9, p. 851-856, set. 2016.
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