Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
01/08/1992 |
Data da última atualização: |
28/03/2023 |
Autoria: |
HOD, I.; HERZ, A.; ZIMBER, A. |
Afiliação: |
University of Jerusalem, Israel. |
Título: |
Pulmonary carcinoma (Jaagsiekte) of sheep; ultrastructural study of early and advanced tumor lesions. |
Ano de publicação: |
1977 |
Fonte/Imprenta: |
American Journal Pathology, v. 86, n. 3, p. 545-552, Mar. 1977. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Lung carcinoma of sheep (Jaagsiekte) is a bronchiolar-alveolar cell carcinoma. Differences in the ultrastructural patterns of early and advanced lesions of the disease are described. A-type and C-type viruses were observed in advanced tumors and were absent in early lesions. Numerous microtubules were characteristic in the epithelial tumor cells of the early lesions and were absent in the advanced tumor. In comparison to the early lesions, extensive cytosome production, surfactant secretion, and glycogen accumulation were observed in the advanced tumor. The immune response to the early tumor lesion was restricted to the peribronchiolar lymph aggregates, while in the advanced stages of the disease the systemic immune response was markedly increased. |
Palavras-Chave: |
Bronchiolo-Alveolar; Sistema respiratorio. |
Thesagro: |
Doença; Ovino; Pulmão. |
Thesaurus Nal: |
Adenocarcinoma; Animal pathology; Glycogen; Immunology; Lung neoplasms; Sheep diseases. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
LEADER 01546naa a2200277 a 4500 001 1523210 005 2023-03-28 008 1977 bl uuuu u00u1 u #d 100 1 $aHOD, I. 245 $aPulmonary carcinoma (Jaagsiekte) of sheep; ultrastructural study of early and advanced tumor lesions.$h[electronic resource] 260 $c1977 520 $aAbstract: Lung carcinoma of sheep (Jaagsiekte) is a bronchiolar-alveolar cell carcinoma. Differences in the ultrastructural patterns of early and advanced lesions of the disease are described. A-type and C-type viruses were observed in advanced tumors and were absent in early lesions. Numerous microtubules were characteristic in the epithelial tumor cells of the early lesions and were absent in the advanced tumor. In comparison to the early lesions, extensive cytosome production, surfactant secretion, and glycogen accumulation were observed in the advanced tumor. The immune response to the early tumor lesion was restricted to the peribronchiolar lymph aggregates, while in the advanced stages of the disease the systemic immune response was markedly increased. 650 $aAdenocarcinoma 650 $aAnimal pathology 650 $aGlycogen 650 $aImmunology 650 $aLung neoplasms 650 $aSheep diseases 650 $aDoença 650 $aOvino 650 $aPulmão 653 $aBronchiolo-Alveolar 653 $aSistema respiratorio 700 1 $aHERZ, A. 700 1 $aZIMBER, A. 773 $tAmerican Journal Pathology$gv. 86, n. 3, p. 545-552, Mar. 1977.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |