Data/hora: 19/06/2024 00:31:51

Biblioteca(s): | Embrapa Pantanal.
Data corrente: | 25/02/2000
Data da última atualização: | 31/03/2017
Autoria: | JAMROZ, R. C.; GUERRERO, F. D.; KAMMLAH, D. M.; KUNZ, S. E.
Título: | Role of the kdr and super-kdr sodium channel mutations in pyrethroid resistance: correlation of allelic frequency to resistance level in wild and laboratory populations of horn flies (Haematobia irritans).
Ano de publicação: | 1998
Fonte/Imprenta: | Insect Biochemistry and Molecular Biology, v.28, p.1031-1037, 1998.
Idioma: | Inglês
Conteúdo: | The kdr and super-kdr point mutations found in the insect sodium channel gene are postulated to confer knockdown resistance (kdr) to pyrethroids. Using an allele-specific PCR assay to detect these mutations in individual horn flies, Haematobia irritans (L.), we determined ~the allelic frequency of the kdr and super-kdr mutations in several wild and laboratory populations. Wild populations with very similar allelic frequencies had resistance levels that ranged widely from 3- to 18-fold relative toa susceptible population. Conversely, the kdr allele frequency in a lab population with 17-fold resistance was nearly double thar found in a heavily pressured wild population with 18-fold resistance. We conclude that, althought the kdr mutation confers significant levels of pyrethroid resistance, a subtantial component of resistance in insecticidally pressured populations is conferred by mechanisms that are PBO-suppressible. High super-kdr allele frequencies were detected in two resistant lab populations, but in wild populations with equivalent resistance the super-kdr allele frequency was very low. Interestingly, in over 1200 individuals assayed, the super-kdr mutation was never detected in the absence of the kdr mutation.
Palavras-Chave: | Canal de sodio; Horn fly; Insect; Mosca-do-chifre; Pyrethroid resistance; Sodium channel.
Thesagro: | Haematobia Irritans; Inseto; População.
Thesaurus Nal: | population.
Categoria do assunto: | --
Registro original: | Embrapa Pantanal (CPAP)
Exemplares: | CPAP - (42641-1) - ADC - SP - PP - SP16127 -  - 16127 - DIS