Data/hora: 11/06/2024 23:19:13

Biblioteca(s): 	Embrapa Pantanal.	
Data corrente: 	25/02/2000	
Data da última atualização: 	31/03/2017	
Autoria: 	JAMROZ, R. C.; GUERRERO, F. D.; KAMMLAH, D. M.; KUNZ, S. E.	
Título: 	Role of the kdr and super-kdr sodium channel mutations in pyrethroid resistance: correlation of allelic frequency to resistance level in wild and laboratory populations of horn flies (Haematobia irritans).	
Ano de publicação: 	1998	
Fonte/Imprenta: 	Insect Biochemistry and Molecular Biology, v.28, p.1031-1037, 1998.	
Idioma: 	Inglês	
Conteúdo: 	The kdr and super-kdr point mutations found in the insect sodium channel gene are postulated to confer knockdown resistance (kdr) to pyrethroids. Using an allele-specific PCR assay to detect these mutations in individual horn flies, Haematobia irritans (L.), we determined ~the allelic frequency of the kdr and super-kdr mutations in several wild and laboratory populations. Wild populations with very similar allelic frequencies had resistance levels that ranged widely from 3- to 18-fold relative toa susceptible population. Conversely, the kdr allele frequency in a lab population with 17-fold resistance was nearly double thar found in a heavily pressured wild population with 18-fold resistance. We conclude that, althought the kdr mutation confers significant levels of pyrethroid resistance, a subtantial component of resistance in insecticidally pressured populations is conferred by mechanisms that are PBO-suppressible. High super-kdr allele frequencies were detected in two resistant lab populations, but in wild populations with equivalent resistance the super-kdr allele frequency was very low. Interestingly, in over 1200 individuals assayed, the super-kdr mutation was never detected in the absence of the kdr mutation.	
Palavras-Chave: 	Canal de sodio; Horn fly; Insect; Mosca-do-chifre; Pyrethroid resistance; Sodium channel.	
Thesagro: 	Haematobia Irritans; Inseto; População.	
Thesaurus Nal: 	population.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Pantanal (CPAP)	
Exemplares: 	CPAP - (42641-1) - ADC - SP - PP - SP16127 -  - 16127 - DIS