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Registro Completo |
Biblioteca(s): |
Embrapa Uva e Vinho. |
Data corrente: |
20/11/2013 |
Data da última atualização: |
30/11/2018 |
Tipo da produção científica: |
Documentos |
Autoria: |
TONIETTO, J.; ZANUS, M. C.; FALCADE, I.; GUERRA, C. C. |
Afiliação: |
JORGE TONIETTO, CNPUV; MAURO CELSO ZANUS, CNPUV; IVANIRA FALCADE, UCS; CELITO CRIVELLARO GUERRA, CNPUV. |
Título: |
O regulamento de uso da denominação de origem Vale dos Vinhedos: vinhos finos tranquilos e espumantes. |
Ano de publicação: |
2013 |
Fonte/Imprenta: |
Bento Gonçalves: Embrapa Uva e Vinho, 2013. |
Páginas: |
35 p. |
Descrição Física: |
il., color. |
Série: |
(Embrapa Uva e Vinho. Documentos, 84). |
ISSN: |
1516-8107. |
Idioma: |
Português |
Conteúdo: |
O Regulamento de Uso da Denominação de Origem Vale dos Vinhedos: Vinhos Finos. Tranquilos e Espumantes. A Denominação de Origem Vale dos Vinhedos. O Regulamento de Uso da Denominação de Origem Vale dos Vinhedos. A Operacionalização do Regulamento de Uso da Denominação de Origem Vale dos Vinhedos. |
Palavras-Chave: |
Denominação de origem; Espumante; Regulamento de uso; Rio Grande do Sul; Vale dos vinhedos; Zoneamento. |
Thesagro: |
Legislação; Uva; Vinho; Viticultura. |
Categoria do assunto: |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/94689/1/doc084.pdf
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Marc: |
LEADER 01155nam a2200301 a 4500 001 1971632 005 2018-11-30 008 2013 bl uuuu u0uu1 u #d 022 $a1516-8107. 100 1 $aTONIETTO, J. 245 $aO regulamento de uso da denominação de origem Vale dos Vinhedos$bvinhos finos tranquilos e espumantes. 260 $aBento Gonçalves: Embrapa Uva e Vinho$c2013 300 $a35 p.$cil., color. 490 $a(Embrapa Uva e Vinho. Documentos, 84). 520 $aO Regulamento de Uso da Denominação de Origem Vale dos Vinhedos: Vinhos Finos. Tranquilos e Espumantes. A Denominação de Origem Vale dos Vinhedos. O Regulamento de Uso da Denominação de Origem Vale dos Vinhedos. A Operacionalização do Regulamento de Uso da Denominação de Origem Vale dos Vinhedos. 650 $aLegislação 650 $aUva 650 $aVinho 650 $aViticultura 653 $aDenominação de origem 653 $aEspumante 653 $aRegulamento de uso 653 $aRio Grande do Sul 653 $aVale dos vinhedos 653 $aZoneamento 700 1 $aZANUS, M. C. 700 1 $aFALCADE, I. 700 1 $aGUERRA, C. C.
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Embrapa Uva e Vinho (CNPUV) |
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Registro Completo
Biblioteca(s): |
Embrapa Clima Temperado. |
Data corrente: |
04/08/2023 |
Data da última atualização: |
04/08/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 4 |
Autoria: |
PEREIRA, R. S.; COSTA, V. V.; GOMES, G. L. M.; CAMPANA, P. R. V.; PÁDUA, R. M. de; BARBOSA, M.; OKI, Y.; HEIDEN, G.; FERNANDES, G. W.; OLIVEIRA, D. M. de; SOUZA, D. G.; TEIXEIRA, M. M.; BRAGA, F. C. |
Afiliação: |
ROSÂNGELA SANTOS PEREIRA, Universidade Federal de Minas Gerais; VIVIAN VASCONCELOS COSTA, Universidade Federal de Minas Gerais; GABRIEL LUIZ MENEZES GOMES, Universidade Federal de Minas Gerais; PRISCILLA RODRIGUES VALADARES CAMPANA, Universidade Federal de Minas Gerais; RODRIGO MAIA DE PÁDUA, Universidade Federal de Minas Gerais; MILTON BARBOSA, Universidade Federal de Minas Gerais; YUMI OKI, Universidade Federal de Minas Gerais; GUSTAVO HEIDEN, CPACT; GERALDO WILSON FERNANDES, Universidade Federal de Minas Gerais; DJALMA MENEZES DE OLIVEIRA, Universidade Estadual do Sudoeste da Bahia; DANIELE G. SOUZA, Universidade Federal de Minas Gerais; MAURO MARTINS TEIXEIRA, Universidade Federal de Minas Gerais; FERNÃO CASTRO BRAGA, Universidade Federal de Minas Gerais. |
Título: |
Anti-Zika Virus Activity of Plant Extracts Containing Polyphenols and Triterpenes on Vero CCL-81 and Human Neuroblastoma SH-SY5Y Cells. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Chemistry & Biodiversity, v. 19, n. 4, e202100842, April 2022. |
DOI: |
https://doi.org/10.1002/cbdv.202100842 |
Idioma: |
Inglês |
Conteúdo: |
Zika virus (ZIKV) infection is a global threat associated to neurological disorders in adults and microcephaly in children born to infected mothers. No vaccine or drug is available against ZIKV. We herein report the anti-ZIKV activity of 36 plant extracts containing polyphenols and/or triterpenes. ZIKV-infected Vero CCL-81 cells were treated with samples at non-cytotoxic concentrations, determined by MTT and LDH assays. One third of the extracts elicited concentration-dependent anti-ZIKV effect, with viral loads reduction from 0.4 to 3.8?log units. The 12 active extracts were tested on ZIKV-infected SH-SY5Y cells and significant reductions of viral loads (in log units) were induced by Maytenus ilicifolia (4.5?log), Terminalia phaeocarpa (3.7?log), Maytenus rigida (1.7?log) and Echinodorus grandiflorus (1.7?log) extracts. Median cytotoxic concentration (CC50) of these extracts in Vero cells were higher than in SH-SY5Y lineage. M. ilicifolia (IC50=16.8±10.3??g/mL, SI=3.4) and T. phaeocarpa (IC50=22.0±6.8??g/mL, SI=4.8) were the most active extracts. UPLC-ESI-MS/MS analysis of M. ilicifolia extract led to the identification of 7 triterpenes, of which lupeol and a mixture of friedelin/friedelinol showed no activity against ZIKV. The composition of T. phaeocarpa extract comprises phenolic acids, ellagitannins and flavonoids, as recently reported by us. In conclusion, the anti-ZIKV activity of 12 plant extracts is here described for the first time and polyphenols and triterpenes were identified as the probable bioactive constituents of T. phaeocarpa and M. ilicifolia, respectively. MenosZika virus (ZIKV) infection is a global threat associated to neurological disorders in adults and microcephaly in children born to infected mothers. No vaccine or drug is available against ZIKV. We herein report the anti-ZIKV activity of 36 plant extracts containing polyphenols and/or triterpenes. ZIKV-infected Vero CCL-81 cells were treated with samples at non-cytotoxic concentrations, determined by MTT and LDH assays. One third of the extracts elicited concentration-dependent anti-ZIKV effect, with viral loads reduction from 0.4 to 3.8?log units. The 12 active extracts were tested on ZIKV-infected SH-SY5Y cells and significant reductions of viral loads (in log units) were induced by Maytenus ilicifolia (4.5?log), Terminalia phaeocarpa (3.7?log), Maytenus rigida (1.7?log) and Echinodorus grandiflorus (1.7?log) extracts. Median cytotoxic concentration (CC50) of these extracts in Vero cells were higher than in SH-SY5Y lineage. M. ilicifolia (IC50=16.8±10.3??g/mL, SI=3.4) and T. phaeocarpa (IC50=22.0±6.8??g/mL, SI=4.8) were the most active extracts. UPLC-ESI-MS/MS analysis of M. ilicifolia extract led to the identification of 7 triterpenes, of which lupeol and a mixture of friedelin/friedelinol showed no activity against ZIKV. The composition of T. phaeocarpa extract comprises phenolic acids, ellagitannins and flavonoids, as recently reported by us. In conclusion, the anti-ZIKV activity of 12 plant extracts is here described for the first time and polyphenols and triterpenes w... Mostrar Tudo |
Thesagro: |
Biodiversidade; Extrato Vegetal; Vírus. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1155672/1/Artigo-Anti8208Zika-Virus-Activity-of-Plant-Extracts.pdf
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Marc: |
LEADER 02560naa a2200313 a 4500 001 2155672 005 2023-08-04 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1002/cbdv.202100842$2DOI 100 1 $aPEREIRA, R. S. 245 $aAnti-Zika Virus Activity of Plant Extracts Containing Polyphenols and Triterpenes on Vero CCL-81 and Human Neuroblastoma SH-SY5Y Cells.$h[electronic resource] 260 $c2022 520 $aZika virus (ZIKV) infection is a global threat associated to neurological disorders in adults and microcephaly in children born to infected mothers. No vaccine or drug is available against ZIKV. We herein report the anti-ZIKV activity of 36 plant extracts containing polyphenols and/or triterpenes. ZIKV-infected Vero CCL-81 cells were treated with samples at non-cytotoxic concentrations, determined by MTT and LDH assays. One third of the extracts elicited concentration-dependent anti-ZIKV effect, with viral loads reduction from 0.4 to 3.8?log units. The 12 active extracts were tested on ZIKV-infected SH-SY5Y cells and significant reductions of viral loads (in log units) were induced by Maytenus ilicifolia (4.5?log), Terminalia phaeocarpa (3.7?log), Maytenus rigida (1.7?log) and Echinodorus grandiflorus (1.7?log) extracts. Median cytotoxic concentration (CC50) of these extracts in Vero cells were higher than in SH-SY5Y lineage. M. ilicifolia (IC50=16.8±10.3??g/mL, SI=3.4) and T. phaeocarpa (IC50=22.0±6.8??g/mL, SI=4.8) were the most active extracts. UPLC-ESI-MS/MS analysis of M. ilicifolia extract led to the identification of 7 triterpenes, of which lupeol and a mixture of friedelin/friedelinol showed no activity against ZIKV. The composition of T. phaeocarpa extract comprises phenolic acids, ellagitannins and flavonoids, as recently reported by us. In conclusion, the anti-ZIKV activity of 12 plant extracts is here described for the first time and polyphenols and triterpenes were identified as the probable bioactive constituents of T. phaeocarpa and M. ilicifolia, respectively. 650 $aBiodiversidade 650 $aExtrato Vegetal 650 $aVírus 700 1 $aCOSTA, V. V. 700 1 $aGOMES, G. L. M. 700 1 $aCAMPANA, P. R. V. 700 1 $aPÁDUA, R. M. de 700 1 $aBARBOSA, M. 700 1 $aOKI, Y. 700 1 $aHEIDEN, G. 700 1 $aFERNANDES, G. W. 700 1 $aOLIVEIRA, D. M. de 700 1 $aSOUZA, D. G. 700 1 $aTEIXEIRA, M. M. 700 1 $aBRAGA, F. C. 773 $tChemistry & Biodiversity$gv. 19, n. 4, e202100842, April 2022.
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