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Registro Completo |
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
18/11/2022 |
Data da última atualização: |
17/12/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
THEODORO, J. M. V.; GRANCIERI, M.; GOMES, M. J. C.; TOLEDO, R. C. L.; SÃO JOSÉ, V. P. B. DE; MANTOVANI, H. C.; CARVALHO, C. W. P. de; SILVA, B. P. DA; MARTINO, H. S. D. |
Afiliação: |
JAQUELINE MACIEL VIEIRA THEODORO, UFV; MARIANA GRANCIERI, UFV, UFES; MARIANA JUSTE CONTIN GOMES, UFV; RENATA CELI LOPES TOLEDO, UFV; VINÍCIUS PARZANINI BRILHANTE DE SÃO JOSÉ, UFV; HILÁRIO CUQUETTO MANTOVANI, UFV; CARLOS WANDERLEI PILER DE CARVALHO, CTAA; BÁRBARA PEREIRA DA SILVA, UFV; HÉRCIA STAMPINI DUARTE MARTINO, UFV. |
Título: |
Germinated millet (Pennisetum glaucum (L.) R. Br.) flour improved the gut function and its microbiota composition in rats fed with high-fat high-fructose diet. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
International Journal Of Environmental Research And Public Health, v. 19, n. 22, 15217, p. 1-14, 2022. |
DOI: |
https://doi.org/10.3390/ijerph192215217 |
Idioma: |
Inglês |
Conteúdo: |
Germinated millet (Pennisetum glaucum (L.) R. Br.) is a source of phenolic compounds that has potential prebiotic action. This study aims at evaluating the action of germinated pearl millet on gut function and its microbiota composition in Wistar rats fed with a high-fat high-fructose (HFHF) diet. In the first stage, lasting eight weeks, the experiment consisted of two groups: AIN93M (n = 10) and HFHF group (n = 20). In the second stage, which lasted ten weeks, the animals of the AIN-93M group (n = 10) were kept, while the HFHF group was dismembered into HFHF (HFHF diet, n = 10) and HFHF + millet (HFHF added 28.6% of germinated millet flour, n = 10) groups. After the 18th week, the urine of the animals was collected for the analysis of lactulose and mannitol intestinal permeability by urinary excretion. The histomorphometry was analyzed on the proximal colon and the fecal pH, concentration of short-chain fatty acids (SCFA), and sequencing of microbiota were performed in cecum content. The Mothur v.1.44.3 software was used for data analysis of sequencing. Alpha diversity was estimated by Chao1, Shannon, and Simpson indexes. Beta diversity was assessed by PCoA (Principal Coordinate Analysis). The functional predictive analysis was performed with PICRUSt2 software (version 2.1.2?b). Functional traits attributed to normalized OTU abundance were determined by the Kyoto Encyclopedia of Genes and Genomes (KEGG). In the results, germinated millet flour reduced Oscillibacter genus and Desulfobacterota phylum, while increasing the Eggerthellaceae family. Furthermore, germinated millet flour: increased beta diversity, cecum weight, and cecum/body weight ratio; improved gut histological parameters by increasing the depth and thickness of the crypt and the goblet cell count (p < 0.05); reduced (p < 0.05) the fecal pH and mannitol urinary excretion; increased (p < 0.05) the propionate short-chain fatty acid concentration. Thus, germinated millet has the potential to improve the composition of gut microbiota and the intestinal function of rats fed with an HFHF diet. MenosGerminated millet (Pennisetum glaucum (L.) R. Br.) is a source of phenolic compounds that has potential prebiotic action. This study aims at evaluating the action of germinated pearl millet on gut function and its microbiota composition in Wistar rats fed with a high-fat high-fructose (HFHF) diet. In the first stage, lasting eight weeks, the experiment consisted of two groups: AIN93M (n = 10) and HFHF group (n = 20). In the second stage, which lasted ten weeks, the animals of the AIN-93M group (n = 10) were kept, while the HFHF group was dismembered into HFHF (HFHF diet, n = 10) and HFHF + millet (HFHF added 28.6% of germinated millet flour, n = 10) groups. After the 18th week, the urine of the animals was collected for the analysis of lactulose and mannitol intestinal permeability by urinary excretion. The histomorphometry was analyzed on the proximal colon and the fecal pH, concentration of short-chain fatty acids (SCFA), and sequencing of microbiota were performed in cecum content. The Mothur v.1.44.3 software was used for data analysis of sequencing. Alpha diversity was estimated by Chao1, Shannon, and Simpson indexes. Beta diversity was assessed by PCoA (Principal Coordinate Analysis). The functional predictive analysis was performed with PICRUSt2 software (version 2.1.2?b). Functional traits attributed to normalized OTU abundance were determined by the Kyoto Encyclopedia of Genes and Genomes (KEGG). In the results, germinated millet flour reduced Oscillibacter genus an... Mostrar Tudo |
Palavras-Chave: |
Alimentos integrais; Beta diversity; Intestinal permeability; Prebióticos; Saúde intestinal. |
Thesagro: |
Tecnologia de Alimento. |
Thesaurus Nal: |
Food technology; Goblet cells; Prebiotics; Whole grain foods. |
Categoria do assunto: |
Q Alimentos e Nutrição Humana |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1148424/1/ijerph-19-15217.pdf
|
Marc: |
LEADER 03270naa a2200349 a 4500 001 2148424 005 2022-12-17 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3390/ijerph192215217$2DOI 100 1 $aTHEODORO, J. M. V. 245 $aGerminated millet (Pennisetum glaucum (L.) R. Br.) flour improved the gut function and its microbiota composition in rats fed with high-fat high-fructose diet.$h[electronic resource] 260 $c2022 520 $aGerminated millet (Pennisetum glaucum (L.) R. Br.) is a source of phenolic compounds that has potential prebiotic action. This study aims at evaluating the action of germinated pearl millet on gut function and its microbiota composition in Wistar rats fed with a high-fat high-fructose (HFHF) diet. In the first stage, lasting eight weeks, the experiment consisted of two groups: AIN93M (n = 10) and HFHF group (n = 20). In the second stage, which lasted ten weeks, the animals of the AIN-93M group (n = 10) were kept, while the HFHF group was dismembered into HFHF (HFHF diet, n = 10) and HFHF + millet (HFHF added 28.6% of germinated millet flour, n = 10) groups. After the 18th week, the urine of the animals was collected for the analysis of lactulose and mannitol intestinal permeability by urinary excretion. The histomorphometry was analyzed on the proximal colon and the fecal pH, concentration of short-chain fatty acids (SCFA), and sequencing of microbiota were performed in cecum content. The Mothur v.1.44.3 software was used for data analysis of sequencing. Alpha diversity was estimated by Chao1, Shannon, and Simpson indexes. Beta diversity was assessed by PCoA (Principal Coordinate Analysis). The functional predictive analysis was performed with PICRUSt2 software (version 2.1.2?b). Functional traits attributed to normalized OTU abundance were determined by the Kyoto Encyclopedia of Genes and Genomes (KEGG). In the results, germinated millet flour reduced Oscillibacter genus and Desulfobacterota phylum, while increasing the Eggerthellaceae family. Furthermore, germinated millet flour: increased beta diversity, cecum weight, and cecum/body weight ratio; improved gut histological parameters by increasing the depth and thickness of the crypt and the goblet cell count (p < 0.05); reduced (p < 0.05) the fecal pH and mannitol urinary excretion; increased (p < 0.05) the propionate short-chain fatty acid concentration. Thus, germinated millet has the potential to improve the composition of gut microbiota and the intestinal function of rats fed with an HFHF diet. 650 $aFood technology 650 $aGoblet cells 650 $aPrebiotics 650 $aWhole grain foods 650 $aTecnologia de Alimento 653 $aAlimentos integrais 653 $aBeta diversity 653 $aIntestinal permeability 653 $aPrebióticos 653 $aSaúde intestinal 700 1 $aGRANCIERI, M. 700 1 $aGOMES, M. J. C. 700 1 $aTOLEDO, R. C. L. 700 1 $aSÃO JOSÉ, V. P. B. DE 700 1 $aMANTOVANI, H. C. 700 1 $aCARVALHO, C. W. P. de 700 1 $aSILVA, B. P. DA 700 1 $aMARTINO, H. S. D. 773 $tInternational Journal Of Environmental Research And Public Health$gv. 19, n. 22, 15217, p. 1-14, 2022.
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Registro original: |
Embrapa Agroindústria de Alimentos (CTAA) |
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Registros recuperados : 14 | |
1. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | GOMES, M. J. C.; MARTINO, H. S. D.; KOLBA, N.; CHENG, J.; AGARWAL, N.; ROCHA, M. de M.; TAKO, E. Zinc biofortified Cowpea (Vigna unguiculata L. Walp.) soluble extracts modulate assessed cecal bacterial pulations and gut morphology In Vivo (Gallus gallus). Frontiers in Bioscience - Landmark, v. 27, n. 5, 140, 2022.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Meio-Norte. |
| ![Visualizar detalhes do registro](/consulta/web/img/visualizar.png) ![Acesso ao objeto digital](/consulta/web/img/pdf.png) ![Imprime registro no formato completo](/consulta/web/img/print.png) |
3. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | MARTINO, H. S. D.; DIAS, D. M.; GOMES, M. J. C.; ALVES, N. E. G.; MOREIRA, M. E. de C.; NUTTI, M. R. Alimentos alvo para a biofortificação apresentam elevada qualidade proteica e ação hipoglicemiante em ratos wistar. In: REUNIÃO DE BIOFORTIFICAÇÃO NO BRASIL, 5., 2015, São Paulo. Anais... Brasília, DF: Embrapa, 2015. p. 70-73 T213. Título equivalente: Staple food crops targeted for biofortification have high protein quality and hypoglycemic effect in wistar rats.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Agroindústria de Alimentos. |
| ![Visualizar detalhes do registro](/consulta/web/img/visualizar.png) ![Acesso ao objeto digital](/consulta/web/img/pdf.png) ![Imprime registro no formato completo](/consulta/web/img/print.png) |
4. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | MARTINO, H. S. D.; DIAS, D. M.; MOREIRA, M. E. de C.; GOMES, M. J. C.; TOLEDO, R. C. L.; NUTTI, M. R.; SANT'ANA, H. M. P. Rice and beans targeted for biofortification combined with high carotenoid content crops (sweet potato and pumpkin) regulate transcriptional mechanisms increasing iron bioavailability. In: REUNIÃO DE BIOFORTIFICAÇÃO NO BRASIL, 5., 2015, São Paulo. Anais... Brasília, DF: Embrapa, 2015. T212. p. 66-69. Título de texto em inglês e português. Titulo equivalente: Arroz e feijão alvo para a biofortificação combinados com culturas com alto conteúdo de carotenoides (batata-doce e abóbora) regulam mecanismos transcricionais aumentando a...Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Agroindústria de Alimentos. |
| ![Visualizar detalhes do registro](/consulta/web/img/visualizar.png) ![Acesso ao objeto digital](/consulta/web/img/pdf.png) ![Imprime registro no formato completo](/consulta/web/img/print.png) |
5. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | DIAS, D. M.; MOREIRA, M. E. DE C.; GOMES, M. J. C.; TOLEDO, R. C. L.; NUTTI, M. R.; SANT'ANA, H. M. P.; MARTINO, H. S. D. Rice and bean targets for biofortification combined with high carotenoid content crops regulate transcriptional mechanisms increasing iron bioavailability. Nutrients, v. 7, p. 9683-9696, 2015.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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6. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | LUCIO, H. G.; LOPES, R. de K. S. O.; GOMES, M. J. C.; GRANCIERI, M.; QUEIROZ, V. A. V.; SILVA, B.; MARTINO, H. S. D. Refeição simbiótica contendo sorgo extrusado associado a probiótico (Bifidobacterium longum) melhora saúde intestinal sem alterar a microbiota intestinal de pacientes com doença renal crônica. In: SIMPÓSIO LATINO AMERICANO DE CIÊNCIA DE ALIMENTOS E NUTRIÇÃO, 15., 2023, Campinas. A revolução da ciência de alimentos e nutrição: alimentando o mundo de forma sustentável: caderno [eletrônico] de resumos. Campinas: Galoá, 2023.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Milho e Sorgo. |
| ![Visualizar detalhes do registro](/consulta/web/img/visualizar.png) ![Acesso restrito ao objeto digital](/consulta/web/img/lock.png) ![Imprime registro no formato completo](/consulta/web/img/print.png) |
7. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | MARTINO, H.; MARTINEZ, O. D. M.; GRANCIERI, M.; GOMES, M. J. C.; SILVA, B. P. da; SÃO JOSÉ, V.; TOLEDO, R. C. L.; QUEIROZ, V. A. V. Sorghum flour BRS 305 hybrid has the potential to modulate the intestinal microbiota of rats fed with a high-fat high-fructose diet. In: INTERNATIONAL CONGRESS ON BIOACTIVE COMPOUNDS, 2.; INTERNATIONAL WORKSHOP ON BIOACTIVE COMPOUNDS, 3., 2022, Campinas. Personal nutrition, ageing and food science: proceedings. Campinas: Unicamp, 2022.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Milho e Sorgo. |
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8. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | THEODORO, J. M. V.; GRANCIERI, M.; GOMES, M. J. C.; TOLEDO, R. C. L.; SÃO JOSÉ, V. P. B. DE; MANTOVANI, H. C.; CARVALHO, C. W. P. de; SILVA, B. P. DA; MARTINO, H. S. D. Germinated millet (Pennisetum glaucum (L.) R. Br.) flour improved the gut function and its microbiota composition in rats fed with high-fat high-fructose diet. International Journal Of Environmental Research And Public Health, v. 19, n. 22, 15217, p. 1-14, 2022.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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9. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | MARTINO, H. S. D.; DIAS, D. M.; GOMES, M. J. C.; ALVES, N. E. G.; MOREIRA, M. E. de C.; DANTAS, M. I. S.; RIBEIRO, S. M. R.; NUTTI, M. R. Iron bioavailability of carotenoids and iron enhanced content crops. Nutrire, São Paulo, v. 39, p. 13, maio 2014. Suplemento. Edição dos Resumos do Bioavailability 2014, Foz do Iguaçu, maio 2014.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Agroindústria de Alimentos. |
| ![Visualizar detalhes do registro](/consulta/web/img/visualizar.png) ![Acesso ao objeto digital](/consulta/web/img/pdf.png) ![Imprime registro no formato completo](/consulta/web/img/print.png) |
10. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | GOMES, M. J. C.; LIMA, S. L. S.; ALVES, N. E. G.; ASSIS, A.; MOREIRA, M. E. C.; TOLEDO, R. C. L.; ROSA, C. O. B.; TEIXEIRA, O. R.; BASSINELLO, P. Z.; MEJÍA, E. G. de; MARTINO, H. S. D. Common bean protein hydrolysate modulates lipid metabolism and prevents endothelial dysfunction in BALB/c mice fed an atherogenic diet. Nutrition, Metabolism & Cardiovascular Diseases, v. 30, n. 1, p. 141-150, Jan. 2020.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Arroz e Feijão. |
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11. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | GOMES, M. J. C.; INFANTE, R. A.; SILVA, B. P. da; MOREIRA, M. E. de C.; DIAS, D. M.; LOPES, R. de C. S. O.; TOLEDO, R. C. L.; QUEIROZ, V. A. V.; MARTINO, H. S. D. Sorghum extrusion process combined with biofortified sweet potato contributed for high iron bioavailability in Wistar rats. Journal of Cereal Science, London, v. 75, p. 213-219, 2017.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Milho e Sorgo. |
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12. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | ALVES, N. E. G.; GOMES, M. J. C.; VASCONCELOS, C. M.; LIMA, A. C.; LIMA, S. L. S. DE; BRITO, E. S. de; BASSINELLO, P. Z.; MARTINO, H. S. D. Six months under uncontrolled relative humidity and room temperature changes technological characteristics and maintains the physicochemical and functional properties of carioca beans (Phaseolus vulgaris L.). Food Chemistry, v. 342, 128390, 2021.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Arroz e Feijão. |
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13. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | DIAS, D. M.; GOMES, M. J. C.; MOREIRA, M. E. de C.; NATAL, D.; SILVA, R. R.; NUTTI, M. R.; MATTA, S. L. da; SANT'ANA, H. M. P.; MARTINO, H. S. D. Staple food crops from Brazilian Biofortification Program have high protein quality and hypoglycemic action in Wistar rats. Food Science and Technology, v. 40, n. 1, p. 140-149, jan. mar. 2020. ahead of print Epub Nov 04, 2019.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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14. | ![Imagem marcado/desmarcado](/consulta/web/img/desmarcado.png) | LIMA, S. L. S. de; GOMES, M. J. C.; SILVA, B. P. da; ALVES, N. E. G.; TOLEDO, R. C. L.; THEODORO, J. M. V.; MOREIRA, M. E. de C.; BENTO, J. A. C.; BASSINELLO, P. Z.; MATTA, S. L. P. da; GONZALEZ DE MEJÍA, E.; MARTINO, H. S. D. Whole flour and protein hydrolysate from common beans reduce the inflammation in BALB/c mice fed with high fat high cholesterol diet. Food Research International, v. 122, p. 330-339, Aug. 2019.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Arroz e Feijão. |
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Registros recuperados : 14 | |
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Nenhum registro encontrado para a expressão de busca informada. |
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