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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
18/09/2018 |
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Data da última atualização: |
18/09/2018 |
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Autoria: |
COLES, G. C.; TRITSCHLER, J. P.; GIORDANO, D. J.; LASTE, N. J.; SCHMIDT, A. L. |
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Título: |
Larval development test for detection of anthelmintic resistant nematodes. |
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Ano de publicação: |
1988 |
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Fonte/Imprenta: |
Research in Veterinary Science, v. 45, n. 1, p. 50-53, Jul. 1988. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: The growth, using freshly cultured Escherichia coli with ampicillin or heat-treated lyophilised E coli as a food source, of the larvae of the mouse nematode Nematospiroides dubius and the infectivity of resulting third stage larvae were determined. Concentrations of E coli between 0.5 and 1 mg dry weight ml-1 permitted optimal larval development for both N dubius and Trichostrongylus colubriformis. Development of larvae of susceptible and cambendazole-resistant strains of Haemonchus contortus in thiabendazole solutions showed clear differences between the strains and the larval development test was more sensitive than the egg hatch test. The test also detected a levamisole resistant strain of H contortus, although the degree of resistance could not be adequately measured. It is concluded that the test can be run with any anthelmintic to which resistance is suspected. |
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Palavras-Chave: |
Drug effects; Nematospiroides dubiu. |
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Thesaurus Nal: |
Anthelmintics; Cambendazole; Drug resistance; Haemonchus; Levamisole; Nematoda; Pharmacology; Thiabendazole. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01673naa a2200289 a 4500
001 2095942
005 2018-09-18
008 1988 bl uuuu u00u1 u #d
100 1 $aCOLES, G. C.
245 $aLarval development test for detection of anthelmintic resistant nematodes.
260 $c1988
520 $aAbstract: The growth, using freshly cultured Escherichia coli with ampicillin or heat-treated lyophilised E coli as a food source, of the larvae of the mouse nematode Nematospiroides dubius and the infectivity of resulting third stage larvae were determined. Concentrations of E coli between 0.5 and 1 mg dry weight ml-1 permitted optimal larval development for both N dubius and Trichostrongylus colubriformis. Development of larvae of susceptible and cambendazole-resistant strains of Haemonchus contortus in thiabendazole solutions showed clear differences between the strains and the larval development test was more sensitive than the egg hatch test. The test also detected a levamisole resistant strain of H contortus, although the degree of resistance could not be adequately measured. It is concluded that the test can be run with any anthelmintic to which resistance is suspected.
650 $aAnthelmintics
650 $aCambendazole
650 $aDrug resistance
650 $aHaemonchus
650 $aLevamisole
650 $aNematoda
650 $aPharmacology
650 $aThiabendazole
653 $aDrug effects
653 $aNematospiroides dubiu
700 1 $aTRITSCHLER, J. P.
700 1 $aGIORDANO, D. J.
700 1 $aLASTE, N. J.
700 1 $aSCHMIDT, A. L.
773 $tResearch in Veterinary Science$gv. 45, n. 1, p. 50-53, Jul. 1988.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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