| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Gado de Leite. |
|
Data corrente: |
04/04/2023 |
|
Data da última atualização: |
22/08/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
ROCHA, R. de F. B.; GARCIA, A. O.; OTTO, P. I.; SILVA, M. V. G. B.; MARTINS, M. F.; MACHADO, M. A.; PANETTO, J. C. do C.; GUIMARÃES, S. E. F. |
|
Afiliação: |
RENATA DE FÁTIMA BRETANHA ROCHA, Universidade Federal de Viçosa; ARIELLY OLIVEIRA GARCIA, Universidade Federal de Viçosa; PAMELA ITAJARA OTTO, Universidade Federal de Santa Maria; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; MARTA FONSECA MARTINS, CNPGL; MARCO ANTONIO MACHADO, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; SIMONE ELIZA FACIONI GUIMARÃES, Universidade Federal de Viçosa. |
|
Título: |
Runs of homozygosity and signatures of selection for number of oocytes and embryos in the Gir Indicine cattle. |
|
Ano de publicação: |
2023 |
|
Fonte/Imprenta: |
Mammalian Genome, v. 34, p. 482-496, 2023. |
|
DOI: |
https://doi.org/10.1007/s00335-023-09989-w |
|
Idioma: |
Inglês |
|
Conteúdo: |
Runs of homozygosity (ROH) and signatures of selection are the results of selection processes in livestock species that have been shown to afect several traits in cattle. The aim of the current work was to verify the profle of ROH and inbreeding depression in the number of total (TO) and viable oocytes (VO) and the number of embryos (EMBR) in Gir Indicine cattle. In addition, we aim to identify signatures of selection, genes, and enriched regions between Gir subpopulations sorted by breeding value for these traits. The genotype fle contained 2093 animals and 420,718 SNP markers. Breeding values used to sort Gir animals were previously obtained. ROH and signature of selection analyses were performed using PLINK software, followed by ROH-based (FROH) and pedigree-based inbreeding (Fped) and a search for genes and their functions. An average of 50±8.59 ROHs were found per animal. ROHs were separated into classes according to size, ranging from 1 to 2 Mb (ROH1?2Mb: 58.17%), representing ancient inbreeding, ROH2?4Mb (22.74%), ROH4-8Mb (11.34%), ROH8-16Mb (5.51%), and ROH>16Mb (2.24%). Combining our results, we conclude that the increase in general FROH and Fped signifcantly decreases TO and VO; however, in diferent chromosomes traits can increase or decrease with FROH. In the analysis for signatures of selection, we identifed 15 genes from 47 signifcant genomic regions, indicating diferences in populations with high and low breeding value for the three traits. |
|
Palavras-Chave: |
Homozigose; Ovócito. |
|
Thesagro: |
Bovino; Embrião Animal; Gado Gir. |
|
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
|
Marc: |
LEADER 02311naa a2200277 a 4500
001 2152954
005 2023-08-22
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1007/s00335-023-09989-w$2DOI
100 1 $aROCHA, R. de F. B.
245 $aRuns of homozygosity and signatures of selection for number of oocytes and embryos in the Gir Indicine cattle.$h[electronic resource]
260 $c2023
520 $aRuns of homozygosity (ROH) and signatures of selection are the results of selection processes in livestock species that have been shown to afect several traits in cattle. The aim of the current work was to verify the profle of ROH and inbreeding depression in the number of total (TO) and viable oocytes (VO) and the number of embryos (EMBR) in Gir Indicine cattle. In addition, we aim to identify signatures of selection, genes, and enriched regions between Gir subpopulations sorted by breeding value for these traits. The genotype fle contained 2093 animals and 420,718 SNP markers. Breeding values used to sort Gir animals were previously obtained. ROH and signature of selection analyses were performed using PLINK software, followed by ROH-based (FROH) and pedigree-based inbreeding (Fped) and a search for genes and their functions. An average of 50±8.59 ROHs were found per animal. ROHs were separated into classes according to size, ranging from 1 to 2 Mb (ROH1?2Mb: 58.17%), representing ancient inbreeding, ROH2?4Mb (22.74%), ROH4-8Mb (11.34%), ROH8-16Mb (5.51%), and ROH>16Mb (2.24%). Combining our results, we conclude that the increase in general FROH and Fped signifcantly decreases TO and VO; however, in diferent chromosomes traits can increase or decrease with FROH. In the analysis for signatures of selection, we identifed 15 genes from 47 signifcant genomic regions, indicating diferences in populations with high and low breeding value for the three traits.
650 $aBovino
650 $aEmbrião Animal
650 $aGado Gir
653 $aHomozigose
653 $aOvócito
700 1 $aGARCIA, A. O.
700 1 $aOTTO, P. I.
700 1 $aSILVA, M. V. G. B.
700 1 $aMARTINS, M. F.
700 1 $aMACHADO, M. A.
700 1 $aPANETTO, J. C. do C.
700 1 $aGUIMARÃES, S. E. F.
773 $tMammalian Genome$gv. 34, p. 482-496, 2023.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Acesso ao texto completo restrito à biblioteca da Embrapa Recursos Genéticos e Biotecnologia. Para informações adicionais entre em contato com cenargen.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
|
Data corrente: |
03/05/2005 |
|
Data da última atualização: |
10/05/2022 |
|
Autoria: |
DALMOLIN, C. C.; SILVA, F. R. da; MELLO, L. V.; RIGDEN, D. J.; CASTRO, M. E. B. de. |
|
Título: |
Nucleotide sequence and phylogenetic analyses of the DNA polymerase gene of Anticarsia gemmatalis nucleopolyhedrovirus. |
|
Ano de publicação: |
2005 |
|
Fonte/Imprenta: |
Virus Research, v. 110, n. 1-2, p. 99-109, 2005. |
|
Idioma: |
Português |
|
Conteúdo: |
The DNA polymerase from Anticarsia gemmatalis nucleopolyhedrovirus (AgMNPV) was identified and sequenced, and its amino acid sequence was compared with other viral DNA polymerases to identify conserved regions and to reconstruct a phylogenetic tree. The sequence analysis of the AgMNPV DNA polymerase gene revealed the presence of a 2976 nucleotides open reading frame (ORF) encoding a polypeptide of 991 amino acid residues with a predicted molecular mass of 114.7 kDa. Among the baculovirus DNA polymerase genes identified to date, the AgMNPV DNA polymerase gene shared maximum amino acid sequence identity with the DNA polymerase gene of Choristoneura fumiferana nucleopolyhedrovirus defective strain (CfDEFNPV) (94%). The alignment of 140 virus sequences, 23 of them from baculovirus, showed that, of the 10 conserved regions identified, 5 are exclusive to baculoviruses (R1, R5, R9, R6 and R10), only 2 of them (R6 and R10) previously described as such in the literature. Our analysis, based on their positions in the AgMNPV DNA polymerase model, suggests that R9 and R10 could interact with DNA. Phylogenetic analysis of DNA polymerase sequences places the enzyme from AgMNPV within the cluster containing the polymerases of Group I Nucleopolyhedrovirus and suggests that the AgMNPV DNA polymerase is more closely related to that of CfDEFNPV than to those of other baculoviruses. |
|
Palavras-Chave: |
Anticarsia gemmatalis nucleopolyhedrovirus; Gene DNA polimerase. |
|
Thesagro: |
Filogenia. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02049naa a2200205 a 4500
001 1185643
005 2022-05-10
008 2005 bl uuuu u00u1 u #d
100 1 $aDALMOLIN, C. C.
245 $aNucleotide sequence and phylogenetic analyses of the DNA polymerase gene of Anticarsia gemmatalis nucleopolyhedrovirus.$h[electronic resource]
260 $c2005
520 $aThe DNA polymerase from Anticarsia gemmatalis nucleopolyhedrovirus (AgMNPV) was identified and sequenced, and its amino acid sequence was compared with other viral DNA polymerases to identify conserved regions and to reconstruct a phylogenetic tree. The sequence analysis of the AgMNPV DNA polymerase gene revealed the presence of a 2976 nucleotides open reading frame (ORF) encoding a polypeptide of 991 amino acid residues with a predicted molecular mass of 114.7 kDa. Among the baculovirus DNA polymerase genes identified to date, the AgMNPV DNA polymerase gene shared maximum amino acid sequence identity with the DNA polymerase gene of Choristoneura fumiferana nucleopolyhedrovirus defective strain (CfDEFNPV) (94%). The alignment of 140 virus sequences, 23 of them from baculovirus, showed that, of the 10 conserved regions identified, 5 are exclusive to baculoviruses (R1, R5, R9, R6 and R10), only 2 of them (R6 and R10) previously described as such in the literature. Our analysis, based on their positions in the AgMNPV DNA polymerase model, suggests that R9 and R10 could interact with DNA. Phylogenetic analysis of DNA polymerase sequences places the enzyme from AgMNPV within the cluster containing the polymerases of Group I Nucleopolyhedrovirus and suggests that the AgMNPV DNA polymerase is more closely related to that of CfDEFNPV than to those of other baculoviruses.
650 $aFilogenia
653 $aAnticarsia gemmatalis nucleopolyhedrovirus
653 $aGene DNA polimerase
700 1 $aSILVA, F. R. da
700 1 $aMELLO, L. V.
700 1 $aRIGDEN, D. J.
700 1 $aCASTRO, M. E. B. de
773 $tVirus Research$gv. 110, n. 1-2, p. 99-109, 2005.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
