Data/hora: 17/06/2024 16:22:07

Biblioteca(s): 	Embrapa Caprinos e Ovinos.	
Data corrente: 	30/06/2004	
Data da última atualização: 	08/10/2010	
Autoria: 	TASENDE, C.; MEIKLE, A.; RODRÍGUEZ-PIÑÓN, M.; FORSBERG, M.; GARÓFALO, E. G.	
Título: 	Estrogen and progesterone receptor content in the pituitary gland and uterus of progesterone-primed and gonadotropin releasing hormone-treated anestrous ewes.	
Ano de publicação: 	2002	
Fonte/Imprenta: 	Theriogenology, v. 57, n. 6, p. 1719-1731, 2002.	
Idioma: 	Inglês	
Conteúdo: 	The objective of this work was to investigate the effect of progesterone (P) and gonadotropin-releasing hormone (GnRH) treatment on estrogen receptor (ER) and P receptor (PR) concentrations in the pituitary gland and uterus of anestrous ewes. Ewes were either not treated (group C, n = 4); were treated with 0.33 g P-controlled internal drug release (P-CIDR) for 10 days (group P, n = 4), with GnRH, 6.7 ng i.v. injections every 2 h for 18 h followed by a 4 ug bolus administration of Receptal at 20 h (group GnRH, n = 4), or with a combination of the P and GnRH treatment (group P + GnRH, n = 3). Ewes were humanely killed either at the beginning of the experiment (group C), when the CIDR was removed (group P), or 24 h after the GnRH bolus treatment (groups GnRH and P + GnRH). Progesterone treatment increased serum P concentrations, indicating that the treatment was effective. AlI GnRH treated ewes had similar luteinizing hormone (LH) surges, which lasted 8 h. At slaughter, estradiol (E2) concentrations in the GnRH group were higher than in groups C, P, and P + GnRH. Treatment with GnRH increased more than 10-fold the content of ER and PR in the pituitary gland without altering steroid receptor concentrations in the uterus. When GnRH was combined with P the uterine receptor contents were higher than with P treatment alone. The treatment with P decreased ER and PR content in the uterus, but had no effect on the pituitary gland. The results show that regulation by P and GnRH of ER and PR content in anestrous ewes is tissue-specific.	
Palavras-Chave: 	Anestro; Receptor.	
Thesagro: 	Ciclo Estral; Endocrinologia; Estrógeno; Ovelha; Ovino; Progesterona; Reprodução Animal.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPC - (16995-1) - ADC - AP - PP -  -  -  - DIS