Data/hora: 21/09/2024 10:19:38

Biblioteca(s): 	Embrapa Agricultura Digital.	
Data corrente: 	08/01/2010	
Data da última atualização: 	15/01/2020	
Autoria: 	CASTRO, A. de; FRONZA, C. F.; HERAI, R. H.; ALVES, D.	
Afiliação: 	ALEXANDRE DE CASTRO, CNPTIA; CARLOS F. FRONZA, Unifesp; ROBERTO HIROCHI HERAI, IB/Unicamp; DOMINGOS ALVES, USP.	
Título: 	Evidence of deterministic evolution in the immunological memory process.	
Ano de publicação: 	2009	
Fonte/Imprenta: 	In: INTERNATIONAL SYMPOSIUM ON MATHEMATICAL AND COMPUTATIONAL BIOLOGY, 9., 2009, Brasília, DF. Proceedings... Brasília, DF: BIOMAT Institute for Advanced Studies of Biosystems, 2009.	
Páginas: 	p. 1-14.	
DOI: 	10.1142/9789814304900_0004	
Idioma: 	Inglês	
Conteúdo: 	In this paper, we study the behavior of immune memory against antigenic mutation. Using a dynamic model proposed by one of the authors in a previous study, we have performed simulations of several inoculations, where in each virtual sample the viral population undergo mutations. Our results suggest that the sustainability of the immunizations is dependent on viral variability and that the memory lifetimes are not random, what condradicts what was suggested by Tarlinton et al.. We show that what may cause an apparent random behavior of the immune memory is the antigenic variability.	
Palavras-Chave: 	Evolução determinística; Memória imunológica; Mutação antigênica.	
Thesagro: 	Mutação.	
Thesaurus Nal: 	Memory; Mutation.	
Categoria do assunto: 	X Pesquisa, Tecnologia e Engenharia	
Registro original: 	Embrapa Agricultura Digital (CNPTIA)	
Exemplares: 	CNPTIA - (14438-1) - UPC - AA - PP -  -  - 2010.00015 - DES
CNPTIA - (14438-2) - UPC - AA - DD -  -  -  - DIS