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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
10/04/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
REGATIERI, I. C.; URI, R. A.; FERRAZ, G. de C.; QUEIROZ-NETO, A. de. |
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Afiliação: |
INAÊ CRISTINA REGATIERI, FCAV/UNESP; ROGÉRIO ABDALLAH CURI, FMVZ/UNESP; GUILHERME DE CAMARGO FERRAZ, FCAV/UNESP; ANTNIO DE QUEIROZ-NETO, FCAV/UNESP. |
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Título: |
Candidate genes for performance in horses, including monocarboxylate transporters. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 1, p. 66-72, janeiro. 2017. |
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Idioma: |
Inglês |
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Conteúdo: |
Some horse breeds are highly selected for athletic activities. The athletic potential of each animal can be measured by its performance in sports. High athletic performance depends on the animal capacity to produce energy through aerobic and anaerobic metabolic pathways, among other factors. Transmembrane proteins called monocarboxylate transporters, mainly the isoform 1 (MCT1) and its ancillary protein CD147, can help the organism to adapt to physiological stress caused by physical exercise, transporting lactate and H+ ions. Horse breeds are selected for different purposes so we might expect differences in the amount of those proteins and in the genotypic frequencies for genes that play a significant role in the performance of the animals. The study of MCT1 and CD147 gene polymorphisms, which can affect the formation of the proteins and transport of lactate and H+, can provide enough information to be used for selection of athletic horses increasingly resistant to intense exercise. Two other candidate genes, the PDK4 and DMRT3, have been associated with athletic potential and indicated as possible markers for performance in horses. The oxidation of fatty acids is highly effective in generating ATP and is controlled by the expression of PDK4 (pyruvate dehydrogenase kinase, isozyme 4) in skeletal muscle during and after exercise. The doublesex and mab-3 related transcription factor 3 (DMRT3) gene encodes an important transcription factor in the setting of spinal cord circuits controlling ovement in vertebrates and may be associated with gait performance in horses. This review describes how the monocarboxylate transporters work during physical exercise in athletic horses and the influence of polymorphisms in candidate genes for athletic performance in horses. MenosSome horse breeds are highly selected for athletic activities. The athletic potential of each animal can be measured by its performance in sports. High athletic performance depends on the animal capacity to produce energy through aerobic and anaerobic metabolic pathways, among other factors. Transmembrane proteins called monocarboxylate transporters, mainly the isoform 1 (MCT1) and its ancillary protein CD147, can help the organism to adapt to physiological stress caused by physical exercise, transporting lactate and H+ ions. Horse breeds are selected for different purposes so we might expect differences in the amount of those proteins and in the genotypic frequencies for genes that play a significant role in the performance of the animals. The study of MCT1 and CD147 gene polymorphisms, which can affect the formation of the proteins and transport of lactate and H+, can provide enough information to be used for selection of athletic horses increasingly resistant to intense exercise. Two other candidate genes, the PDK4 and DMRT3, have been associated with athletic potential and indicated as possible markers for performance in horses. The oxidation of fatty acids is highly effective in generating ATP and is controlled by the expression of PDK4 (pyruvate dehydrogenase kinase, isozyme 4) in skeletal muscle during and after exercise. The doublesex and mab-3 related transcription factor 3 (DMRT3) gene encodes an important transcription factor in the setting of spinal cord circuits... Mostrar Tudo |
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Palavras-Chave: |
Fatigue; Monocarboxylate transporters; Polymorphisms. |
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Thesaurus Nal: |
Genes; Horses; Lactates. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/158785/1/Candidate-genes-for-performance-in-horses.pdf
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Marc: |
LEADER 02449naa a2200229 a 4500
001 2068271
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aREGATIERI, I. C.
245 $aCandidate genes for performance in horses, including monocarboxylate transporters.
260 $c2017
520 $aSome horse breeds are highly selected for athletic activities. The athletic potential of each animal can be measured by its performance in sports. High athletic performance depends on the animal capacity to produce energy through aerobic and anaerobic metabolic pathways, among other factors. Transmembrane proteins called monocarboxylate transporters, mainly the isoform 1 (MCT1) and its ancillary protein CD147, can help the organism to adapt to physiological stress caused by physical exercise, transporting lactate and H+ ions. Horse breeds are selected for different purposes so we might expect differences in the amount of those proteins and in the genotypic frequencies for genes that play a significant role in the performance of the animals. The study of MCT1 and CD147 gene polymorphisms, which can affect the formation of the proteins and transport of lactate and H+, can provide enough information to be used for selection of athletic horses increasingly resistant to intense exercise. Two other candidate genes, the PDK4 and DMRT3, have been associated with athletic potential and indicated as possible markers for performance in horses. The oxidation of fatty acids is highly effective in generating ATP and is controlled by the expression of PDK4 (pyruvate dehydrogenase kinase, isozyme 4) in skeletal muscle during and after exercise. The doublesex and mab-3 related transcription factor 3 (DMRT3) gene encodes an important transcription factor in the setting of spinal cord circuits controlling ovement in vertebrates and may be associated with gait performance in horses. This review describes how the monocarboxylate transporters work during physical exercise in athletic horses and the influence of polymorphisms in candidate genes for athletic performance in horses.
650 $aGenes
650 $aHorses
650 $aLactates
653 $aFatigue
653 $aMonocarboxylate transporters
653 $aPolymorphisms
700 1 $aURI, R. A.
700 1 $aFERRAZ, G. de C.
700 1 $aQUEIROZ-NETO, A. de.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 1, p. 66-72, janeiro. 2017.
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Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agrobiologia. Para informações adicionais entre em contato com cnpab.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agrobiologia. |
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Data corrente: |
30/01/2004 |
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Data da última atualização: |
30/01/2004 |
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Autoria: |
ASSIS, R. L. de. |
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Título: |
Agroecologia: alternativa para o desenvolvimento rural sustentável a partir da integração de ações públicas e privadas. |
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Ano de publicação: |
2003 |
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Fonte/Imprenta: |
In: SEMINÁRIO ECONOMIA DO MEIO AMBIENTE: REGULAÇÃO ESTATAL E AUTO-REGULAÇÃO EMPRESARIAL PARA O DESENVOLVIMENTO SUSTENTÁVEL, 3., 2003, Campinas. Anais... Campinas: UNICAMP, 2003. |
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Páginas: |
13 p. |
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Idioma: |
Português |
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Conteúdo: |
O conceito de desenvolvimento sustentável e suas possibilidades de implementação. A dimensão local do desenvolvimento. Alternativas de política ambiental. Desenvolvimento agrícola sustentável a partir de uma ação local. |
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Palavras-Chave: |
Agroecologia; Alternative agriculture; Sustainability. |
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Thesagro: |
Agricultura Alternativa; Agricultura Sustentável; Desenvolvimento Sustentável; Ecologia Vegetal. |
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Thesaurus NAL: |
plant ecology; sustainable agriculture. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01113naa a2200241 a 4500
001 1612118
005 2004-01-30
008 2003 bl --- 0-- u #d
100 1 $aASSIS, R. L. de
245 $aAgroecologia$balternativa para o desenvolvimento rural sustentável a partir da integração de ações públicas e privadas.
260 $c2003
300 $a13 p.
520 $aO conceito de desenvolvimento sustentável e suas possibilidades de implementação. A dimensão local do desenvolvimento. Alternativas de política ambiental. Desenvolvimento agrícola sustentável a partir de uma ação local.
650 $aplant ecology
650 $asustainable agriculture
650 $aAgricultura Alternativa
650 $aAgricultura Sustentável
650 $aDesenvolvimento Sustentável
650 $aEcologia Vegetal
653 $aAgroecologia
653 $aAlternative agriculture
653 $aSustainability
773 $tIn: SEMINÁRIO ECONOMIA DO MEIO AMBIENTE: REGULAÇÃO ESTATAL E AUTO-REGULAÇÃO EMPRESARIAL PARA O DESENVOLVIMENTO SUSTENTÁVEL, 3., 2003, Campinas. Anais... Campinas: UNICAMP, 2003.
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Embrapa Agrobiologia (CNPAB) |
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