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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
10/03/2017 |
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Data da última atualização: |
10/03/2017 |
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Autoria: |
DUBEY, J. P. |
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Título: |
Experimental toxoplasmosis in sheep fed Toxoplasma gondii oocysts. |
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Ano de publicação: |
1984 |
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Fonte/Imprenta: |
International Goat and Sheep Research, v. 2 n. 2, p. 93-104, 1984. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Four lambs, 8 rams and 8 ewes in mid pregnancy were each inoculated orally with 10,000 infective oocysts of the GT-1 strain of T. gondii. The lambs were killed 4, 7, 14 and 21 days postinoculation (DPI) and their small intestines, mesenteric lymph nodes, liver, lungs, muscle and brain were titrated in mice to determine the extent of multiplication of T. gondii. In mesenteric lymph nodes and small intestines 10,000-fold more T. gondii multiplied than in other tissues. Mesenteric lymphadenitis and enteritis were the main lesions and T. gondii was demonstrated in lesions. To determine the presence of encysted T. gondii, the rams were killed 97, 132, 146, 153, 160, 160, 173 and 173 DPI and their liver, kidneys, brain, heart, diaphragm, testes, and thigh muscles were digested in acid pepsin and inoculated into mice. T. gondii cysts were demonstrated in the heart of 7 rams, in liver, thigh muscles, and diaphragm of 6, in kidneys of 5, in brain of 4 and testes of 1 ram. The 8th ram escaped infection. The ewes were killed 7, 8, 11, 15, 18, 21 45 and 49 DPI and their placentas were titrated in mice and fetal tissues were inoculated in mice. Three of the 8 ewes aborted or had dead lambs, 7, 8 and 46 DPI. T. gondii was isolated from the placenta, 15 DPI and not at 7,8 and 11 DPI, and from the fetal tissues at 18 DPI. Lesions due to toxoplasmosis were not found in placenta, or fetuses examined between 7 and 21 DPI. Necrosis was found in fetal cotyledons 45 and 46 DPI. Lesions or Toxoplasma were not observed in tissues of any of the rams or ewes. MenosAbstract: Four lambs, 8 rams and 8 ewes in mid pregnancy were each inoculated orally with 10,000 infective oocysts of the GT-1 strain of T. gondii. The lambs were killed 4, 7, 14 and 21 days postinoculation (DPI) and their small intestines, mesenteric lymph nodes, liver, lungs, muscle and brain were titrated in mice to determine the extent of multiplication of T. gondii. In mesenteric lymph nodes and small intestines 10,000-fold more T. gondii multiplied than in other tissues. Mesenteric lymphadenitis and enteritis were the main lesions and T. gondii was demonstrated in lesions. To determine the presence of encysted T. gondii, the rams were killed 97, 132, 146, 153, 160, 160, 173 and 173 DPI and their liver, kidneys, brain, heart, diaphragm, testes, and thigh muscles were digested in acid pepsin and inoculated into mice. T. gondii cysts were demonstrated in the heart of 7 rams, in liver, thigh muscles, and diaphragm of 6, in kidneys of 5, in brain of 4 and testes of 1 ram. The 8th ram escaped infection. The ewes were killed 7, 8, 11, 15, 18, 21 45 and 49 DPI and their placentas were titrated in mice and fetal tissues were inoculated in mice. Three of the 8 ewes aborted or had dead lambs, 7, 8 and 46 DPI. T. gondii was isolated from the placenta, 15 DPI and not at 7,8 and 11 DPI, and from the fetal tissues at 18 DPI. Lesions due to toxoplasmosis were not found in placenta, or fetuses examined between 7 and 21 DPI. Necrosis was found in fetal cotyledons 45 and 46 DPI. Lesions ... Mostrar Tudo |
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Palavras-Chave: |
Abortion; Experimental infection; Infecção experimental. |
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Thesagro: |
Aborto; Cordeiro; Doença animal; Ovino; Prenhez; Toxoplasma Gondii; Toxoplasmose. |
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Thesaurus Nal: |
Pregnancy; Sheep; Toxoplasmosis. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02294naa a2200277 a 4500
001 2066684
005 2017-03-10
008 1984 bl uuuu u00u1 u #d
100 1 $aDUBEY, J. P.
245 $aExperimental toxoplasmosis in sheep fed Toxoplasma gondii oocysts.
260 $c1984
520 $aAbstract: Four lambs, 8 rams and 8 ewes in mid pregnancy were each inoculated orally with 10,000 infective oocysts of the GT-1 strain of T. gondii. The lambs were killed 4, 7, 14 and 21 days postinoculation (DPI) and their small intestines, mesenteric lymph nodes, liver, lungs, muscle and brain were titrated in mice to determine the extent of multiplication of T. gondii. In mesenteric lymph nodes and small intestines 10,000-fold more T. gondii multiplied than in other tissues. Mesenteric lymphadenitis and enteritis were the main lesions and T. gondii was demonstrated in lesions. To determine the presence of encysted T. gondii, the rams were killed 97, 132, 146, 153, 160, 160, 173 and 173 DPI and their liver, kidneys, brain, heart, diaphragm, testes, and thigh muscles were digested in acid pepsin and inoculated into mice. T. gondii cysts were demonstrated in the heart of 7 rams, in liver, thigh muscles, and diaphragm of 6, in kidneys of 5, in brain of 4 and testes of 1 ram. The 8th ram escaped infection. The ewes were killed 7, 8, 11, 15, 18, 21 45 and 49 DPI and their placentas were titrated in mice and fetal tissues were inoculated in mice. Three of the 8 ewes aborted or had dead lambs, 7, 8 and 46 DPI. T. gondii was isolated from the placenta, 15 DPI and not at 7,8 and 11 DPI, and from the fetal tissues at 18 DPI. Lesions due to toxoplasmosis were not found in placenta, or fetuses examined between 7 and 21 DPI. Necrosis was found in fetal cotyledons 45 and 46 DPI. Lesions or Toxoplasma were not observed in tissues of any of the rams or ewes.
650 $aPregnancy
650 $aSheep
650 $aToxoplasmosis
650 $aAborto
650 $aCordeiro
650 $aDoença animal
650 $aOvino
650 $aPrenhez
650 $aToxoplasma Gondii
650 $aToxoplasmose
653 $aAbortion
653 $aExperimental infection
653 $aInfecção experimental
773 $tInternational Goat and Sheep Research$gv. 2 n. 2, p. 93-104, 1984.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 2 | |
| 1. |  | COSENDEY-KEZENLEITE, R. I. J.; OLIVEIRA, F. C. R. de; FRAZÃO-TEIXEIRA, E.; DUBEY, J. P.; SOUZA, G. N. de; FERREIRA, A. M. R.; LILENBAUM, W. Occurrence and risk factors associated to Toxoplasma gondii infection in sheep from Rio de Janeiro, Brazil. Tropical Animal Health and Production, v. 46, n. 8, p. 1463-1466, 2014.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Gado de Leite. |
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| 2. | | ANDRADE, L. H. M.; LUGARINI, C.; OLIVEIRA, R. A. S.; SILVA, L. T. R.; MARVULO, M. F. V.; GARCIA, J. E.; DUBEY, J. P.; SILVA, J. C. R. Ocorrência de anticorpos anti-Toxoplasma gondii em aves silvestres de três Unidades de Conservação Federais da Paraíba e da Bahia. Pesquisa Veterinária Brasileira,Rio de Janeiro, v. 36, n. 2, p. 103-107, fev. 2016.| Biblioteca(s): Embrapa Unidades Centrais. |
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| Registros recuperados : 2 | |
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