Data/hora: 18/06/2024 13:16:22

Biblioteca(s): | Embrapa Caprinos e Ovinos.
Data corrente: | 06/02/2018
Data da última atualização: | 06/02/2018
Autoria: | DAVIS, S. L.; ANFINSON, M.
Título: | Dose-response influence of prostaglandin E and somatostatin on plasma levels of growth hormone. Prolactin and thyrotropin in sheep.
Ano de publicação: | 1975
Fonte/Imprenta: | Journal of Animal Science, v. 41, n. 1, p. 172?177, 1975.
DOI: | https://doi.org/10.2527/jas1975.411172x
Idioma: | Inglês
Conteúdo: | Abstract: Ten ewe lambs (approximately 40 kg) were used to determine the influence of prostaglandin E 1 (PGE1) and synthetic somatotropin-release inhibiting factor (SRIF) on plasma levels of ovine growth hormone (GH), prolactin (PRL) and thyrotropin (TSH). Intravenous injection of PGE1 (20 and 100/ag/kg) stimulated a dose-related increase in plasma levels of GH (20 + 6 and 50 + 10 ng/ml), respectively. Intravenous injection of SRIF (500 ~g), significantly (P<.05) depressed the GH stimulation by PGE 1 (20/2g/kg), while lower doses (5 and 50 /lg) were ineffective. The highest dose of PGE 1 (100/2g/kg) also stimulated a significant (P<.01) increase in plasma levels of PRL. One and 10/~g doses of PGE1/kg had no influence, while the 20 #g/kg dose appeared to stimulate PRL secretion although the response was quite variable. Treatment with SRIF (500 ~tg) significantly (P<.05) reduced the PRL stimulation by PGEI at 20 /.tg/kg. However the variable PRL response to the 20/2g/kg dose of PGE 1 makes this observation inconclusive. Neither PGE 1 nor SRIF exerted an influence on plasma TSH. These data demonstrate the dose-related stimulatory effect of intravenously administered PGE 1 on secretion of GH and PRL.
Palavras-Chave: | Growth hormone; Prostaglandin E1.
Thesaurus Nal: | Prolactin; Prostaglandins; Sheep; Somatostatin; Thyrotropin.
Categoria do assunto: | L Ciência Animal e Produtos de Origem Animal
Registro original: | Embrapa Caprinos e Ovinos (CNPC)
Exemplares: | CNPC - (36300-1) - ADD - AP - PP -  -  -  - DIS