Data/hora: 16/06/2024 03:38:48

Biblioteca(s): | Embrapa Pecuária Sudeste.
Data corrente: | 20/10/2016
Data da última atualização: | 07/11/2018
Autoria: | PEREIRA, G. L.; MATTEIS, R. de; REGITANO, L. C. de A.; CHARDULO, L. A. L.; CURI, R. A.
Afiliação: | GUILHERME L. PEREIRA, UNESP; RAFAEL DE MATTEIS, UNESP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; LUÍS ARTUR L. CHARDULO, UNESP; ROGÉRIO A. CURI, UNESP.
Título: | MSTN, CKM, and DMRT3 gene variants in different lines of quarter horses.
Ano de publicação: | 2016
Fonte/Imprenta: | Journal of Equine Veterinary Science, v.39, p.33-37, apr. 2016.
Volume: | 39
Páginas: | 33-37
DOI: | http://dx.doi.org/10.1016/j.jevs.2015.09.001
Idioma: | Inglês
Conteúdo: | and creatine kinase muscle (CKM) (g.22999655C>A) genes have been associated with optimum racing distance and muscle development and racing performance in Thoroughbred horses, respectively. Considering that, since its formation, the Quarter Horse breed has received important genetic influence from the English breed, the genes cited become important candidates for athletic performance in the racing line of the American breed. An SNP in the equine doublesex and mab-3-related transcription factor 3 (DMRT3) gene (g.22999655C>A) has been described, which is responsible for the gait phenotype in homozygous individuals. Using a sample of 296 Quarter Horses of the racing line and 68 animals of the cutting line, the objective of this study was to compare the frequencies of the three SNPs cited above between a random subsample of animals of the cutting line (n ¼ 20) and animals with extreme phenotypes for racing performance (n ¼ 20 per extreme phenotype). The MSTN SNP showed practically no variation, with the observation of only one heterozygous animal (CT) in the cutting line, suggesting that this gene has been under great selective pressure within the racing segment. The CKM gene variant studied was found to be polymorphic, but no significant associates were observed between its alleles and the different lines or groups. Two animals carrying the CA heterozygous DMRT3 genotype were identified in the group with poor racing performance and one in the cutting line, indicating that this variant can be a limiting factor for the development of greater speeds.
Palavras-Chave: | Cavalo de um quarto; Equine; Gens variantes; SNP.
Thesagro: | Eqüino.
Categoria do assunto: | G Melhoramento Genético
Registro original: | Embrapa Pecuária Sudeste (CPPSE)
Exemplares: | CPPSE - (23847-1) - UPC - AP - DD - PROCI-2016.00111 - PER - 2016.00155 - DIS