Registro Completo |
Biblioteca(s): |
Embrapa Instrumentação. |
Data corrente: |
22/12/1999 |
Data da última atualização: |
22/12/1999 |
Autoria: |
CRAIK, D. J. ed. |
Afiliação: |
Centre for Drug Design and Development, University of Queensland. |
Título: |
NMR in drug design. |
Ano de publicação: |
1996 |
Fonte/Imprenta: |
Boca Raton: CRC, 1996. |
Páginas: |
476p. il. |
ISBN: |
0-8493-7824-9 |
Idioma: |
Inglês |
Conteúdo: |
Drug design and discovery: where next? The role of NMR in drug design and development. Studies of drug-receptor interactions by NMR: theory and applications. Protein structure determination using NMR spectroscopy. Conformational analysis of drug molecules. Conformational analysis of peptides: application to drug design. Protein-ligand interactions: examples in drug design. NMR sutdies of ligand binding to dihydrofolate reductase and their application in drug design. Studies of drug-calmodulin binding using isotopically labelled protein. Flexibility and function in the HIV-1 protease. DNA as a target for drug action: complexes of intercalating antibiotics. Drug binding to the minor groove of DNA. |
Palavras-Chave: |
Drogas; Espectroscopia; Instrumentacao; NMR; Nuclear magnetic resonance; Projeto; Ressonancia magnetica nuclear; RMN; Technique; Tecnica. |
Thesaurus Nal: |
design; drugs; instrumentation; spectroscopy. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01400nam a2200301 a 4500 001 1025767 005 1999-12-22 008 1996 bl uuuu 00u1 u #d 020 $a0-8493-7824-9 100 1 $aCRAIK, D. J. ed. 245 $aNMR in drug design. 260 $aBoca Raton: CRC$c1996 300 $a476p. il. 520 $aDrug design and discovery: where next? The role of NMR in drug design and development. Studies of drug-receptor interactions by NMR: theory and applications. Protein structure determination using NMR spectroscopy. Conformational analysis of drug molecules. Conformational analysis of peptides: application to drug design. Protein-ligand interactions: examples in drug design. NMR sutdies of ligand binding to dihydrofolate reductase and their application in drug design. Studies of drug-calmodulin binding using isotopically labelled protein. Flexibility and function in the HIV-1 protease. DNA as a target for drug action: complexes of intercalating antibiotics. Drug binding to the minor groove of DNA. 650 $adesign 650 $adrugs 650 $ainstrumentation 650 $aspectroscopy 653 $aDrogas 653 $aEspectroscopia 653 $aInstrumentacao 653 $aNMR 653 $aNuclear magnetic resonance 653 $aProjeto 653 $aRessonancia magnetica nuclear 653 $aRMN 653 $aTechnique 653 $aTecnica
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Registro original: |
Embrapa Instrumentação (CNPDIA) |