Data/hora: 23/06/2024 13:32:40

Biblioteca(s): | Embrapa Instrumentação.
Data corrente: | 22/12/1999
Data da última atualização: | 22/12/1999
Autoria: | CRAIK, D. J. ed.
Afiliação: | Centre for Drug Design and Development, University of Queensland.
Título: | NMR in drug design.
Ano de publicação: | 1996
Fonte/Imprenta: | Boca Raton: CRC, 1996.
Páginas: | 476p. il.
ISBN: | 0-8493-7824-9
Idioma: | Inglês
Conteúdo: | Drug design and discovery: where next? The role of NMR in drug design and development. Studies of drug-receptor interactions by NMR: theory and applications. Protein structure determination using NMR spectroscopy. Conformational analysis of drug molecules. Conformational analysis of peptides: application to drug design. Protein-ligand interactions: examples in drug design. NMR sutdies of ligand binding to dihydrofolate reductase and their application in drug design. Studies of drug-calmodulin binding using isotopically labelled protein. Flexibility and function in the HIV-1 protease. DNA as a target for drug action: complexes of intercalating antibiotics. Drug binding to the minor groove of DNA.
Palavras-Chave: | Drogas; Espectroscopia; Instrumentacao; NMR; Nuclear magnetic resonance; Projeto; Ressonancia magnetica nuclear; RMN; Technique; Tecnica.
Thesaurus Nal: | design; drugs; instrumentation; spectroscopy.
Categoria do assunto: | --
Registro original: | Embrapa Instrumentação (CNPDIA)
Exemplares: | CNPDIA - (4381-1) - ADC - LV - -- - 615.1901 - C887n - 1997.00081 - DIS