Data/hora: 25/06/2024 05:48:47

Biblioteca(s): 	Embrapa Instrumentação.	
Data corrente: 	11/01/2024	
Data da última atualização: 	11/06/2024	
Autoria: 	SANTOS, F. V. dos; SIQUEIRA, R. L.; RAMOS, L. de M.; YOSHIOKA, S. A.; BRANCIFORTI, M. C.; CORREA, D. S.	
Afiliação: 	FRANCISCO VIEIRA DOS SANTOS, UNIVERSITY OF SÃO PAULO (USP); RENATO LUIZ SIQUEIRA, FEDERAL UNIVERSITY OF SAO CARLOS (UFSCAR); LUCAS DE MORAIS RAMOS, UNIVERSITY OF SAO PAULO (USP); SÉRGIO AKINOBU YOSHIOKA, UNIVERSITY OF SAO PAULO (USP); MÁRCIA CRISTINA BRANCIFORTI, UNIVERSITY OF SAO PAULO (USP); DANIEL SOUZA CORREA, CNPDIA.	
Título: 	Silk fibroin-derived electrospun materials for biomedical applications: A review.	
Ano de publicação: 	2024	
Fonte/Imprenta: 	International Journal of Biological Macromolecules, v. 254, 127641, 2024.	
Páginas: 	34 p.	
ISSN: 	0141-8130	
DOI: 	https://doi.org/10.1016/j.ijbiomac.2023.127641	
Idioma: 	Inglês	
Conteúdo: 	Electrospinning is a versatile technique for fabricating polymeric fibers with diameters ranging from micro- to nanoscale, exhibiting multiple morphologies and arrangements. By combining silk fibroin (SF) with synthetic and/or natural polymers, electrospun materials with outstanding biological, chemical, electrical, physical, mechanical, and optical properties can be achieved, fulfilling the evolving biomedical demands. This review highlights the remarkable versatility of SF-derived electrospun materials, specifically focusing on their application in tissue regeneration (including cartilage, cornea, nerves, blood vessels, bones, and skin), disease treatment (such as cancer and diabetes), and the development of controlled drug delivery systems. Additionally, we explore the potential future trends in utilizing these nanofibrous materials for creating intelligent biomaterials, incorporating biosensors and wearable sensors for monitoring human health, and also discuss the bottlenecks for its widespread use. This comprehensive overview illuminates the significant impact and exciting prospects of SF-derived electrospun materials in advancing biomedical research and applications.	
Palavras-Chave: 	Biomaterials; Electrospinning; Regenerative medicine; Silk fibroin.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Instrumentação (CNPDIA)	
Exemplares: 	CNPDIA - (18368-1) - UPC - AP - DD - PROCI.24/09 -  - 2024/09 - DIS