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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sul. Para informações adicionais entre em contato com cppsul.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sul. |
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Data corrente: |
03/10/2022 |
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Data da última atualização: |
03/10/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
COMIN, H.; CAMPOS, G. S.; DOMINGUES, R.; GASPAR, E. B.; SOLLERO, B. P.; CARDOSO, F. F. |
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Afiliação: |
HELENA B. COMIN, Universidade Federal de Pelotas; G. S. CAMPOS, Universidade Estadual Paulista; ROBERT DOMINGUES, CPPSUL; EMANUELLE BALDO GASPAR, CPPSUL; BRUNA PENA SOLLERO, GPM; FERNANDO FLORES CARDOSO, CPPSUL. |
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Título: |
Genetic parameters and accuracy of traditional and genomic breeding values for resistance to infectious bovine keratoconjunctivitis in Hereford. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Livestock Science, v. 264, 105078, Oct. 2022. |
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Idioma: |
Inglês |
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Conteúdo: |
A B S T R A C T The objectives of this research were to estimate genetic parameters using a threshold animal model by traditional (pedigree and phenotype), single-step genomic BLUP (ssGBLUP) and Weighted ssGBLUP (WssGBLUP) methods, and assess the relative increase in accuracy with the addition of genomic information on the estimation of breeding values for the incidence of infectious bovine keratoconjunctivitis (IBK) in Hereford cattle. The data used in this study were obtained from animals belonging to four farms of Delta G breeders association and genetically evaluated by the Delta G breeding program, born between 2015 and 2017, totaling 293,716 individuals in the pedigree data and 1,579 phenotypes for IBK (1 = absence of disease or 2 = presence of disease). The genotypic data, after quality control, retained 37,505 SNP markers and 1,401 samples. A Bayesian framework and a threshold animal model were used to estimate variance components and to predict breeding values. Animals with genotype and phenotype for the traits studied were divided into 3 groups by random and k-means clustering cross-validation strategies. The estimate of direct heritability for resistance to IBK was 0.12 ± 0.01 and 0.10 ± 0.01 through PBLUP and ssGBLUP methods. The mean realized prediction accuracies based on linear regression statistics were 0.36, 0.65 and 0.70, respectively for PBLUP, ssGBLUP and WssGBLUP; therefore, the use of the genomic relationship matrices was superior to the pedigree-based method. When using the WssGBLUP method, there was an additional increase in prediction accuracy when compared to the ssGBLUP method, which was already substantially better than PBLUP. The prediction of breeding values using genomic information by the single-step methods should result in more accurate selection decisions compared to traditional pedigree evaluations and, consequently, genomic selection can be readily applied with moderately high reliability to help reduce the incidence of IBK in Hereford cattle. MenosA B S T R A C T The objectives of this research were to estimate genetic parameters using a threshold animal model by traditional (pedigree and phenotype), single-step genomic BLUP (ssGBLUP) and Weighted ssGBLUP (WssGBLUP) methods, and assess the relative increase in accuracy with the addition of genomic information on the estimation of breeding values for the incidence of infectious bovine keratoconjunctivitis (IBK) in Hereford cattle. The data used in this study were obtained from animals belonging to four farms of Delta G breeders association and genetically evaluated by the Delta G breeding program, born between 2015 and 2017, totaling 293,716 individuals in the pedigree data and 1,579 phenotypes for IBK (1 = absence of disease or 2 = presence of disease). The genotypic data, after quality control, retained 37,505 SNP markers and 1,401 samples. A Bayesian framework and a threshold animal model were used to estimate variance components and to predict breeding values. Animals with genotype and phenotype for the traits studied were divided into 3 groups by random and k-means clustering cross-validation strategies. The estimate of direct heritability for resistance to IBK was 0.12 ± 0.01 and 0.10 ± 0.01 through PBLUP and ssGBLUP methods. The mean realized prediction accuracies based on linear regression statistics were 0.36, 0.65 and 0.70, respectively for PBLUP, ssGBLUP and WssGBLUP; therefore, the use of the genomic relationship matrices was superior to the pedigree-based ... Mostrar Tudo |
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Palavras-Chave: |
Resistência a doença; Seleção genômica. |
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Thesagro: |
Gado de Corte; Parâmetro Genético. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02742naa a2200229 a 4500
001 2147076
005 2022-10-03
008 2022 bl uuuu u00u1 u #d
100 1 $aCOMIN, H.
245 $aGenetic parameters and accuracy of traditional and genomic breeding values for resistance to infectious bovine keratoconjunctivitis in Hereford.$h[electronic resource]
260 $c2022
520 $aA B S T R A C T The objectives of this research were to estimate genetic parameters using a threshold animal model by traditional (pedigree and phenotype), single-step genomic BLUP (ssGBLUP) and Weighted ssGBLUP (WssGBLUP) methods, and assess the relative increase in accuracy with the addition of genomic information on the estimation of breeding values for the incidence of infectious bovine keratoconjunctivitis (IBK) in Hereford cattle. The data used in this study were obtained from animals belonging to four farms of Delta G breeders association and genetically evaluated by the Delta G breeding program, born between 2015 and 2017, totaling 293,716 individuals in the pedigree data and 1,579 phenotypes for IBK (1 = absence of disease or 2 = presence of disease). The genotypic data, after quality control, retained 37,505 SNP markers and 1,401 samples. A Bayesian framework and a threshold animal model were used to estimate variance components and to predict breeding values. Animals with genotype and phenotype for the traits studied were divided into 3 groups by random and k-means clustering cross-validation strategies. The estimate of direct heritability for resistance to IBK was 0.12 ± 0.01 and 0.10 ± 0.01 through PBLUP and ssGBLUP methods. The mean realized prediction accuracies based on linear regression statistics were 0.36, 0.65 and 0.70, respectively for PBLUP, ssGBLUP and WssGBLUP; therefore, the use of the genomic relationship matrices was superior to the pedigree-based method. When using the WssGBLUP method, there was an additional increase in prediction accuracy when compared to the ssGBLUP method, which was already substantially better than PBLUP. The prediction of breeding values using genomic information by the single-step methods should result in more accurate selection decisions compared to traditional pedigree evaluations and, consequently, genomic selection can be readily applied with moderately high reliability to help reduce the incidence of IBK in Hereford cattle.
650 $aGado de Corte
650 $aParâmetro Genético
653 $aResistência a doença
653 $aSeleção genômica
700 1 $aCAMPOS, G. S.
700 1 $aDOMINGUES, R.
700 1 $aGASPAR, E. B.
700 1 $aSOLLERO, B. P.
700 1 $aCARDOSO, F. F.
773 $tLivestock Science$gv. 264, 105078, Oct. 2022.
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Registro original: |
Embrapa Pecuária Sul (CPPSUL) |
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| Registros recuperados : 15 | |
| 6. |  | COMIN, H. B.; DOMINGUES, R.; GASPAR, E. B.; SANTOS, J. R. G. de los; CARDOSO, F. F. Genetic differences among Moraxella bovis and Moraxella bovoculi isolates from infectious bovine keratoconjunctivitis (IBK) outbreaks in southern Brazil. Genetics and Molecular Biology, v. 43, n. 2, e20180380, p. 1-7, 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| 7. | | FREITAS, D. S. de; CAMARGO, S. da S.; COMIN, H. B.; DOMINGUES, R.; GASPAR, E. B.; CARDOSO, F. F. Reconhecimento da ceratoconjuntivite infecciosa bovina utilizando imagens termográficas e redes neurais convolucionais. Revista Brasileira de Computação Aplicada, v. 11, n. 3, p.133-145, nov. 2019.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 2 |
| Biblioteca(s): Embrapa Pecuária Sul. |
|  |
| 8. | | COMIN, H. B.; GASPAR, E. B.; DOMINGUES, R.; SANTOS, J. R. G. de los; SCHRAMM, R. C.; CARDOSO, F. F. Descrição de um surto de ceratoconjuntivite infecciosa bovina em animais da raça Hereford em quatro propriedades no Estado do Rio Grande do Sul. In: CONGRESSO DE INICIAÇÃO CIENTÍFICA, 25.; CONGRESSO DE EXTENSÃO E CULTURA, 3.; CONGRESSO DE ENSINO DE GRADUAÇÃO, 2.; ENCONTRO DE PÓS-GRADUAÇÃO, 18., 2016, Pelotas. Conhecimento, sociedade e diversidade: anais. Pelotas: UFPEL, 2016. Enpos.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| 9. | | FREITAS, D. S. de; CAMARGO, S. da S.; COMIN, H. B.; DOMINGUES, R.; GASPAR, E. B.; CARDOSO, F. F. Diagnostico automático de ceratoconjuntivite infecciosa bovina por meio de imagens termográficas e deep learning. In: CONGRESSO BRASILEIRO DE AGROINFORMÁTICA, 12., 2019, Indaiatuba. Anais... Ponta Grossa: SBIAGRO, 2019. p. 172-174. Organizadores: Maria Fernanda Moura, Jayme Garcia Arnal Barbedo, Alaine Margarete Guimarães, Valter Castelhano de Oliveira. SBIAgro 2019.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| 10. | | COMIN, H. B.; GASPAR, E. B.; DOMINGUES, R.; SANTOS, J. R. G. de los; SCHRAMM, R. C.; CARDOSO, F. F. Suceptibilicade de cepas de Moraxella bovis e Moraxella bovoculi frente aos antimicrobianos. In: CONGRESSO DE INICIAÇÃO CIENTÍFICA, 26.; ENCONTRO DE PÓS-GRADUAÇÃO UFPEL, 19.; SEMANA INTEGRADA DE ENSINO, PESQUISA E EXTENSÃO, 3., 2016, Pelotas. Anais... Pelotas: UFPel, 2017.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| 11. | | CARDOSO, F. F.; SOLLERO, B. P.; GOMES, C. C. G.; COMIN, H. B.; ROSO, V. M.; HIGA, R. H.; YOKOO, M. J.; CAETANO, A. R.; AGUILAR, I. Accuracy of genomic prediction for tick resistance in Braford and Hereford cattle. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver, British Columbia, Canada. Proceedings... Champaign: ASAS, 2014. Não paginado.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 12. | | CARDOSO, F. F.; SOLLERO, B. P.; GOMES, C. C. G.; COMIN, H. B.; ROSO, V. M.; HIGA, R. H.; YOKOO, M. J.; CAETANO, A. R.; AGUILAR, I. Accuracy of genomic prediction for tick resistance in Braford and Hereford cattle. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver, British Columbia, Canada. Proceedings... Champaign: ASAS, 2014. Não paginado.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Agricultura Digital. |
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| 13. | | CARDOSO, F. F.; SOLLERO, B. P.; GULIAS-GOMES, C. C.; COMIN, H. B.; ROSO, V. M.; HIGA, R. H.; YOKOO, M. J. I.; CAETANO, A. R.; AGUILAR, I. Accuracy of genomic prediction for tick resistance in Braford and Hereford cattle. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 10., 2014, Vancouver, British Columbia, Canada. Proceedings... Champaign: ASAS, 2014. 1 CD-ROM.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| 14. | | COMIN, H. B.; SOLLERO, B. P.; JUNQUEIRA, V. S.; CARDOSO, L. L.; HIGA, R. H.; CAETANO, A. R.; YOKOO, M. J. I.; CARDOSO, F. F. Controle de qualidade de genótipos e amostras utilizados na seleção genômica das raças Braford e Hereford In: SEMINÁRIO INTERINSTITUCIONAL DE ENSINO, PESQUISA E EXTENSÃO, 18.; MOSTRA DE INICIAÇÃO CIENTÍFICA, 16,; MOSTRA DE EXTENSÃO, 11., 2013, Cruz Alta. Ciência, conhecimento e sociedade de risco: anais. Cruz Alta: Unicruz, 2013.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| 15. | | LOPES, T. R. M.; COMIN, H. B.; DOMINGUES, R.; GIL DE LOS SANTOS, J. R.; CARDOSO, F. F.; GASPAR, E. B. Utilização de imagens termográficas para diagnóstico de ceratoconjuntivite infecciosa bovina em animais da raça Hereford. In: SIMPÓSIO DE INICIAÇÃO CIENTÍFICA DA EMBRAPA PECUÁRIA SUL, 8., 2018, Bagé. Resumos... Bagé: Embrapa Pecuária Sul, 2018. p. 35. (Embrapa Pecuária Sul. Eventos técnicos & científicos, 1). Fernando Flores Cardoso, Daniel Portella Montardo, José Carlos Ferrugem Moraes, Marcos Flávio Silva Borba, Sandro da Silva Camargo, editores técnicos.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| Registros recuperados : 15 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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