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Registro Completo |
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Biblioteca(s): |
Embrapa Meio Norte / UEP-Parnaíba. |
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Data corrente: |
18/07/1996 |
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Data da última atualização: |
18/07/1996 |
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Autoria: |
LIN, J. Y.; HOU, M. J.; CHEN, Y. C. |
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Afiliação: |
National Taiwan University. |
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Título: |
Isolation of toxic and non-toxic lectins from the bitter pear melon Momordica charantia Linn. |
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Ano de publicação: |
1978 |
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Fonte/Imprenta: |
Toxicon, v.16, p.653-660, 1978. |
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Idioma: |
Inglês |
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Conteúdo: |
Toxic and non-toxic lectins, momordin and momordica agglutinin were isolated from Momordica charantia Linn. The mod, wt of momordin and momordica agglutinin were determined to be 23,678 and 31, 762 respectivelyby SDS acrylamide gel electrophoresis and as gel filtration coupled with amino acid analyses. Both lectins are single polypeptide chains. The LD50 of momordin was 5mg per kg body weight and it inhibited proteinbiosynthesis of Ehlich ascites tumor cells. Momordica agglutinin is able to agglutinate the human O type red blood cells at a concentration of 0.5 ug/ml. Galactose of its derivatives are able to inhibit the hemagglutination. |
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Palavras-Chave: |
Lectin; Toxin. |
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Thesagro: |
Lectina; Toxina. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01136naa a2200193 a 4500
001 1077897
005 1996-07-18
008 1978 bl --- 0-- u #d
100 1 $aLIN, J. Y.
245 $aIsolation of toxic and non-toxic lectins from the bitter pear melon Momordica charantia Linn.
260 $c1978
520 $aToxic and non-toxic lectins, momordin and momordica agglutinin were isolated from Momordica charantia Linn. The mod, wt of momordin and momordica agglutinin were determined to be 23,678 and 31, 762 respectivelyby SDS acrylamide gel electrophoresis and as gel filtration coupled with amino acid analyses. Both lectins are single polypeptide chains. The LD50 of momordin was 5mg per kg body weight and it inhibited proteinbiosynthesis of Ehlich ascites tumor cells. Momordica agglutinin is able to agglutinate the human O type red blood cells at a concentration of 0.5 ug/ml. Galactose of its derivatives are able to inhibit the hemagglutination.
650 $aLectina
650 $aToxina
653 $aLectin
653 $aToxin
700 1 $aHOU, M. J.
700 1 $aCHEN, Y. C.
773 $tToxicon$gv.16, p.653-660, 1978.
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Registro original: |
Embrapa Meio Norte / UEP-Parnaíba (CPAMN-UEPP) |
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