Data/hora: 10/06/2024 19:03:14

Biblioteca(s): | Embrapa Caprinos e Ovinos.
Data corrente: | 05/11/2010
Data da última atualização: | 05/11/2010
Autoria: | DENG, C.; MA, R.; YUE, X.; LAN, X.; CHEN, H.; LEI, C.
Título: | Association of IGF-I gene polymorphisms with milk yield and body size in Chinese dairy goats.
Ano de publicação: | 2010
Fonte/Imprenta: | Genetics and Molecular Biology, v. 33, n. 2, p. 266-270, Jun., 2010.
Idioma: | Inglês
Conteúdo: | The association of IGF-I gene polymorphisms with certain traits in 708 individuals of two Chinese dairy-goat breeds (Guanzhong and Xinong Saanen) was investigated. Polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and DNA sequencing methods were employed in screening for genetic variation. Two novel mutations were detected in the 5'-flanking region and in intron 4 of IGF-I gene, viz., g.1617 G > A and g.5752 G > C (accession D26119.2), respectively. The associations of the g.1617 G > A mutation with milk yield and the body size were not significant (p > 0.05). However, in the case of g.5752 G > C, Xinong Saanen dairy goats with the CG genotype presented longer bodies (p < 0.05). Chest circumference (p < 0.05) was larger in Guanzhong goats with the GG genotype. In Xinong Saanen dairy goats with the CC genotype, milk yields were significantly higher during the first and second lactations (p < 0.05). Hence, the g.5752 G > C mutation could facilitate association analysis and serve as a genetic marker for Chinese dairy-goat breeding and genetics.
Palavras-Chave: | Caprino leiteiro; IGF-I gene; PCR-SSCP.
Thesagro: | Genética animal; Leite de cabra; Marcador genético; Polimorfismo genético; Produção; Rendimento.
Categoria do assunto: | G Melhoramento Genético
Registro original: | Embrapa Caprinos e Ovinos (CNPC)
Exemplares: | CNPC - (23543-1) - ADD - AP - PP -  -  -  - DIS