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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
14/06/2017 |
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Data da última atualização: |
14/06/2017 |
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Autoria: |
LYE, S. J.; WLODEK, M. E.; CHALLIS, J. R. G. |
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Título: |
Possible role of uterine contractions in the short-term fluctuations of plasma ACTH concentration in fetal sheep. |
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Ano de publicação: |
1985 |
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Fonte/Imprenta: |
Journal of Endocrinology, v. 106, n. 2, p. R9-R11, Aug. 1985. |
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DOI: |
10.1677/joe.0.106R009 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Uterine contractions, induced by the administration of oxytocin to sheep between d 123-144 of pregnancy, were associated with a mean transient decrease in fetal PaO2 of 2.8 mm Hg within 5 min. These changes were associated with a rapid increase in the concentration of ACTH in fetal plasma. There was a significant (P less than 0.05) increase in the percentage change (+40 to +47%) over basal ACTH levels in fetal plasma at +5, +15 and +20 min after oxytocin. Administration of saline had no significant effect on intrauterine pressure, fetal PaO2 or fetal plasma ACTH levels. We speculate that increases in uterine activity and/or transient decreases in fetal PaO2 may contribute to short-term fluctuations in plasma ACTH in fetal sheep. |
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Palavras-Chave: |
Adrenocorticotropic hormone; Drug effects; Fetal Blood. |
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Thesaurus Nal: |
Ewes; Gestation period; Metabolism; Oxygen; Oxytocin; Pharmacology; Pregnancy; Sheep; uterine contraction. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 01593naa a2200301 a 4500
001 2070922
005 2017-06-14
008 1985 bl uuuu u00u1 u #d
024 7 $a10.1677/joe.0.106R009$2DOI
100 1 $aLYE, S. J.
245 $aPossible role of uterine contractions in the short-term fluctuations of plasma ACTH concentration in fetal sheep.
260 $c1985
520 $aAbstract: Uterine contractions, induced by the administration of oxytocin to sheep between d 123-144 of pregnancy, were associated with a mean transient decrease in fetal PaO2 of 2.8 mm Hg within 5 min. These changes were associated with a rapid increase in the concentration of ACTH in fetal plasma. There was a significant (P less than 0.05) increase in the percentage change (+40 to +47%) over basal ACTH levels in fetal plasma at +5, +15 and +20 min after oxytocin. Administration of saline had no significant effect on intrauterine pressure, fetal PaO2 or fetal plasma ACTH levels. We speculate that increases in uterine activity and/or transient decreases in fetal PaO2 may contribute to short-term fluctuations in plasma ACTH in fetal sheep.
650 $aEwes
650 $aGestation period
650 $aMetabolism
650 $aOxygen
650 $aOxytocin
650 $aPharmacology
650 $aPregnancy
650 $aSheep
650 $auterine contraction
653 $aAdrenocorticotropic hormone
653 $aDrug effects
653 $aFetal Blood
700 1 $aWLODEK, M. E.
700 1 $aCHALLIS, J. R. G.
773 $tJournal of Endocrinology$gv. 106, n. 2, p. R9-R11, Aug. 1985.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
