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![](/consulta/web/img/deny.png) | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
01/08/1992 |
Data da última atualização: |
20/06/2023 |
Autoria: |
CAMERON, C. M.; FULS, W. J. P. |
Título: |
Studies on the enhancement of immunity to Corynebacterium pseudotuberculosis. |
Ano de publicação: |
1973 |
Fonte/Imprenta: |
Onderstepoort Journal Veterinary Research, v. 40, n. 3, p. 105-114, 1973. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Experiments were undertaken to enhance the immune response of mice, guinea pigs and sheep to C. pseudotuberculosis vaccine. The antibody response of guinea pigs was not increased either by the simultaneous administration of formalin inactivated vaccine and heterologous live vaccine, or by vaccines grown on special media and extracted with ether : ethanol or sodium lauryl sulphate, or by endotoxin. In mice and sheep the immunity was not enhanced either by the intravenous administration of inactivated vaccines or by the subcutaneous injection of live vaccines prepared from avirulent strains. In sheep an inactivated vaccine, concentrated tenfold, caused a moderate increase in the antibody titre and there was a marked improvement in their immunity. Such sheep were markedly more resistant to the lethal effects of a subacute infection of living bacteria than those that received standard inactivated vaccine. It is concluded that concentrated C. pseudotuberculosis vaccine does not confer an absolute immunity but it would be of value when used shortly before possible exposure to infection, e.g. shearing. |
Thesagro: |
Corynebacterium Pseudotuberculosis; Doença; Linfadenite Caseosa; Ovino. |
Thesaurus Nal: |
Agglutination tests; Bacterial antibodies; Biosynthesis; Endotoxins; Goats; Guinea pigs; Mice; Rabbits; Sheep diseases; Virulence. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
LEADER 01965naa a2200301 a 4500 001 1523737 005 2023-06-20 008 1973 bl uuuu u00u1 u #d 100 1 $aCAMERON, C. M. 245 $aStudies on the enhancement of immunity to Corynebacterium pseudotuberculosis.$h[electronic resource] 260 $c1973 520 $aAbstract: Experiments were undertaken to enhance the immune response of mice, guinea pigs and sheep to C. pseudotuberculosis vaccine. The antibody response of guinea pigs was not increased either by the simultaneous administration of formalin inactivated vaccine and heterologous live vaccine, or by vaccines grown on special media and extracted with ether : ethanol or sodium lauryl sulphate, or by endotoxin. In mice and sheep the immunity was not enhanced either by the intravenous administration of inactivated vaccines or by the subcutaneous injection of live vaccines prepared from avirulent strains. In sheep an inactivated vaccine, concentrated tenfold, caused a moderate increase in the antibody titre and there was a marked improvement in their immunity. Such sheep were markedly more resistant to the lethal effects of a subacute infection of living bacteria than those that received standard inactivated vaccine. It is concluded that concentrated C. pseudotuberculosis vaccine does not confer an absolute immunity but it would be of value when used shortly before possible exposure to infection, e.g. shearing. 650 $aAgglutination tests 650 $aBacterial antibodies 650 $aBiosynthesis 650 $aEndotoxins 650 $aGoats 650 $aGuinea pigs 650 $aMice 650 $aRabbits 650 $aSheep diseases 650 $aVirulence 650 $aCorynebacterium Pseudotuberculosis 650 $aDoença 650 $aLinfadenite Caseosa 650 $aOvino 700 1 $aFULS, W. J. P. 773 $tOnderstepoort Journal Veterinary Research$gv. 40, n. 3, p. 105-114, 1973.
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