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Registro Completo |
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Biblioteca(s): |
Embrapa Alimentos e Territórios. |
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Data corrente: |
09/05/2023 |
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Data da última atualização: |
29/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SABINO, L. B. de S.; COPES, F.; SAULAIS, S.; BRITO, E. S. de; SILVA JÚNIOR, I. J. da; LE, T. C.; MATEESCU, M. A.; MANTOVANI, D. |
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Afiliação: |
LUIZ BRUNO DE SOUSA SABINO, UFC; FRANCESCO COPES, Laval University; SOLÈNE SAULAIS, Université du Québec à Montréal; EDY SOUSA DE BRITO, CNAT; IVANILDO JOSÉ DA SILVA JÚNIOR, UFC; TIEN CANH LE, Université du Québec à Montréal; MIRCEA ALEXANDRU MATEESCU, Université du Québec à Montréal; DIEGO MANTOVANI, Laval University. |
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Título: |
Anthocyanins formulated with carboxymethyl starch for gastric and intestinal delivery. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Molecules, v. 27, n. 21, 7271, p. 1-19, 2022. |
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ISSN: |
1420-3049 |
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DOI: |
https://doi.org/10.3390/molecules27217271 |
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Idioma: |
Inglês |
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Conteúdo: |
Anthocyanins obtained from jambolan have been used as active agents in different carboxymethyl starch-based tablet formulations and their release profiles evaluated in simulated gastric fluids (SGF) and simulated intestinal (SIF) fluids. Structural analysis highlighted a strong interaction between anthocyanins and carboxymethyl starch, evidenced by scanning electron microscopy and infrared analysis. Tablet dissolution behavior varied according to the pH of the media, being controlled by the swelling and/or erosion of the polymeric matrix. Various formulations for immediate, fast, and sustained release of anthocyanins for 30 min, 2 h and 12 h of dissolution have been developed. It was found that monolithic carboxymethyl starch tablets loaded with powdered jambolan extract efficiently afforded the complete delivery (100% of anthocyanins) to different sites of the simulated gastrointestinal tract and ensured the stability of these pigments, which maintained their antioxidant activity. |
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Palavras-Chave: |
Agente bioativo; Antiaterosclerótica; Antiatherosclerotic activities; Antiinflammatory; Antioxidant activities; Antioxidantes; Antitumoral; Bioactive agent delivery; Carboxymethyl starch; Jamelão; Monolithic tablets. |
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Thesagro: |
Antiinflamatório; Fruto. |
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Thesaurus Nal: |
Anthocyanins; Fruit composition; Syzygium cumini. |
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Categoria do assunto: |
S Ciências Biológicas |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1153621/1/CNAT-9.pdf
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Marc: |
LEADER 02218naa a2200421 a 4500
001 2153621
005 2024-02-29
008 2022 bl uuuu u00u1 u #d
022 $a1420-3049
024 7 $ahttps://doi.org/10.3390/molecules27217271$2DOI
100 1 $aSABINO, L. B. de S.
245 $aAnthocyanins formulated with carboxymethyl starch for gastric and intestinal delivery.$h[electronic resource]
260 $c2022
520 $aAnthocyanins obtained from jambolan have been used as active agents in different carboxymethyl starch-based tablet formulations and their release profiles evaluated in simulated gastric fluids (SGF) and simulated intestinal (SIF) fluids. Structural analysis highlighted a strong interaction between anthocyanins and carboxymethyl starch, evidenced by scanning electron microscopy and infrared analysis. Tablet dissolution behavior varied according to the pH of the media, being controlled by the swelling and/or erosion of the polymeric matrix. Various formulations for immediate, fast, and sustained release of anthocyanins for 30 min, 2 h and 12 h of dissolution have been developed. It was found that monolithic carboxymethyl starch tablets loaded with powdered jambolan extract efficiently afforded the complete delivery (100% of anthocyanins) to different sites of the simulated gastrointestinal tract and ensured the stability of these pigments, which maintained their antioxidant activity.
650 $aAnthocyanins
650 $aFruit composition
650 $aSyzygium cumini
650 $aAntiinflamatório
650 $aFruto
653 $aAgente bioativo
653 $aAntiaterosclerótica
653 $aAntiatherosclerotic activities
653 $aAntiinflammatory
653 $aAntioxidant activities
653 $aAntioxidantes
653 $aAntitumoral
653 $aBioactive agent delivery
653 $aCarboxymethyl starch
653 $aJamelão
653 $aMonolithic tablets
700 1 $aCOPES, F.
700 1 $aSAULAIS, S.
700 1 $aBRITO, E. S. de
700 1 $aSILVA JÚNIOR, I. J. da
700 1 $aLE, T. C.
700 1 $aMATEESCU, M. A.
700 1 $aMANTOVANI, D.
773 $tMolecules$gv. 27, n. 21, 7271, p. 1-19, 2022.
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Registro original: |
Embrapa Alimentos e Territórios (CNAT) |
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Registro |
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Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Agroindústria Tropical. |
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Data corrente: |
06/03/2014 |
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Data da última atualização: |
20/04/2017 |
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Tipo da produção científica: |
Comunicado Técnico/Recomendações Técnicas |
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Autoria: |
BASTOS, M. do S. R.; LAURENTINO. L. da S.; SILVA, S. M. F. da; MENDES, L. G.; CANUTO, K. M.; GONÇALVES, N. P.; PEREIRA, R. de C. A. |
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Afiliação: |
MARIA DO SOCORRO ROCHA BASTOS, CNPAT; LARISSA DA SILVA LAURENTINO, UFC; SARAH MARIA FROTA da SILVA, UFC; LUANA GUABIRABA MENDES, UFC; KIRLEY MARQUES CANUTO, CNPAT; NIGÉRIA PEREIRA GONÇALVES, UFC; RITA DE CASSIA ALVES PEREIRA, CNPAT. |
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Título: |
Filme biodegradável de base celulósica incorporado de óleos essenciais. |
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Ano de publicação: |
2013 |
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Fonte/Imprenta: |
Fortaleza: Embrapa Agroindústria Tropical, 2013. |
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Páginas: |
4 p. |
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Série: |
(Embrapa Agroindústria Tropical. Comunicado Técnico, 207). |
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Idioma: |
Português |
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Palavras-Chave: |
Acetato de celulose; Biodegradable film; Essential oil; Filme biodegradável; Óleos essenciais. |
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Thesaurus NAL: |
cellulose acetate. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/98609/1/COT13006.pdf
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Marc: |
LEADER 00844nam a2200265 a 4500
001 1981648
005 2017-04-20
008 2013 bl uuuu u0uu1 u #d
100 1 $aBASTOS, M. do S. R.
245 $aFilme biodegradável de base celulósica incorporado de óleos essenciais.$h[electronic resource]
260 $aFortaleza: Embrapa Agroindústria Tropical$c2013
300 $a4 p.
490 $a(Embrapa Agroindústria Tropical. Comunicado Técnico, 207).
650 $acellulose acetate
653 $aAcetato de celulose
653 $aBiodegradable film
653 $aEssential oil
653 $aFilme biodegradável
653 $aÓleos essenciais
700 1 $aLAURENTINO. L. da S.
700 1 $aSILVA, S. M. F. da
700 1 $aMENDES, L. G.
700 1 $aCANUTO, K. M.
700 1 $aGONÇALVES, N. P.
700 1 $aPEREIRA, R. de C. A.
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Registro original: |
Embrapa Agroindústria Tropical (CNPAT) |
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ID |
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Tipo/Formato |
Classificação |
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