Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
10/07/2017 |
Data da última atualização: |
10/07/2017 |
Autoria: |
BLAIR-WEST, J. R.; BROOK, A. H.; SIMPSON, P. A. |
Título: |
On the question of body fluid volume or sodium status influencing renin release. |
Ano de publicação: |
1977 |
Fonte/Imprenta: |
The Journal of Physiology, v. 267, n. 2, p. 321-338, May, 1977. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: 1. The extent to which renin release is affected by simultaneous changes in body Na and body fluid volume was studied in six sheep. 2. The animals' water intake was restricted for 10-17 days after which they were offered solutions containing varying amounts of NaCl. 3. Plasma renin concentration (PRC) of water restricted sheep was 2-3 times normal. 4. The changes in PRC following drinking were inversely related to the amount of sodium consumed, Na excretion and plasma Na concentration. There was no correlation between the changes of PRC and of plasma volume in so far as the latter is reflected by alterations in plasma protein concentration. 5. We conclude that changes in renin release were related to the animals' handling of NA, and not to alterations in body fluid volume. 6. These findings are compatible with the proposition that renin release was mediated by a macula densa mechanism |
Palavras-Chave: |
Analysis. |
Thesaurus Nal: |
Blood Proteins; Physiology; Renin; Sheep; Sodium; Urine. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 01510naa a2200229 a 4500 001 2072369 005 2017-07-10 008 1977 bl uuuu u00u1 u #d 100 1 $aBLAIR-WEST, J. R. 245 $aOn the question of body fluid volume or sodium status influencing renin release. 260 $c1977 520 $aAbstract: 1. The extent to which renin release is affected by simultaneous changes in body Na and body fluid volume was studied in six sheep. 2. The animals' water intake was restricted for 10-17 days after which they were offered solutions containing varying amounts of NaCl. 3. Plasma renin concentration (PRC) of water restricted sheep was 2-3 times normal. 4. The changes in PRC following drinking were inversely related to the amount of sodium consumed, Na excretion and plasma Na concentration. There was no correlation between the changes of PRC and of plasma volume in so far as the latter is reflected by alterations in plasma protein concentration. 5. We conclude that changes in renin release were related to the animals' handling of NA, and not to alterations in body fluid volume. 6. These findings are compatible with the proposition that renin release was mediated by a macula densa mechanism 650 $aBlood Proteins 650 $aPhysiology 650 $aRenin 650 $aSheep 650 $aSodium 650 $aUrine 653 $aAnalysis 700 1 $aBROOK, A. H. 700 1 $aSIMPSON, P. A. 773 $tThe Journal of Physiology$gv. 267, n. 2, p. 321-338, May, 1977.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |