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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
09/06/2017 |
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Data da última atualização: |
09/06/2017 |
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Autoria: |
WRIGHT, R. D.; BLAIR-WEST, J. R.; NELSON, J. F.; TREGEAR, G. W. |
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Título: |
Local action of parathyroid hormone (1-34) and (1-84) at the parotid gland of sheep. |
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Ano de publicação: |
1982 |
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Fonte/Imprenta: |
Journal of Endocrinology, v. 94, n. 1, p. 37-41, Jul. 1982. |
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DOI: |
10.1677/joe.0.0940037 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Administration of bovine parathyroid hormone (PTH) preparations increased the phosphate concentration in the parotid saliva of sheep. Data on the site of action of PTH (1-84) were obtained by (a) equimolar infusions of PTH (1-84) and (1-34) directly into the arterial blood supply of the vascularly isolated parotid gland in anaesthetized sheep, (b) intravenous infusion of PTH (1-84) at a similar rate and (c) intra-arterial infusion of PTH (1-84) with complete drainage of the venous effluent from the gland during the infusion. Results showed substantial time- and dose-response identity of the two peptides, at 10(-9) to 4 X 10(-9) mol/l in arterial blood, in raising salivary phosphate concentration. The effect of PTH (1-84) was not due to recirculated fragments because the response was obtained when recirculation was prevented by complete venous drainage and little or no response occurred when the same infusion was given i.v. |
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Palavras-Chave: |
Parathyroid gland; Peptide Fragments; Teriparatide. |
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Thesagro: |
Saliva. |
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Thesaurus Nal: |
Cattle; Metabolism; parotid gland; Phosphates; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 01700naa a2200277 a 4500
001 2070718
005 2017-06-09
008 1982 bl uuuu u00u1 u #d
024 7 $a10.1677/joe.0.0940037$2DOI
100 1 $aWRIGHT, R. D.
245 $aLocal action of parathyroid hormone (1-34) and (1-84) at the parotid gland of sheep.
260 $c1982
520 $aAbstract: Administration of bovine parathyroid hormone (PTH) preparations increased the phosphate concentration in the parotid saliva of sheep. Data on the site of action of PTH (1-84) were obtained by (a) equimolar infusions of PTH (1-84) and (1-34) directly into the arterial blood supply of the vascularly isolated parotid gland in anaesthetized sheep, (b) intravenous infusion of PTH (1-84) at a similar rate and (c) intra-arterial infusion of PTH (1-84) with complete drainage of the venous effluent from the gland during the infusion. Results showed substantial time- and dose-response identity of the two peptides, at 10(-9) to 4 X 10(-9) mol/l in arterial blood, in raising salivary phosphate concentration. The effect of PTH (1-84) was not due to recirculated fragments because the response was obtained when recirculation was prevented by complete venous drainage and little or no response occurred when the same infusion was given i.v.
650 $aCattle
650 $aMetabolism
650 $aparotid gland
650 $aPhosphates
650 $aSheep
650 $aSaliva
653 $aParathyroid gland
653 $aPeptide Fragments
653 $aTeriparatide
700 1 $aBLAIR-WEST, J. R.
700 1 $aNELSON, J. F.
700 1 $aTREGEAR, G. W.
773 $tJournal of Endocrinology$gv. 94, n. 1, p. 37-41, Jul. 1982.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
