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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
04/04/2016 |
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Data da última atualização: |
04/04/2016 |
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Autoria: |
RUFF, G. O.; FLURI, A.; LAZARY, S.; VOGT, H. R.; PETERHANS, E.; BERTONI, G. |
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Título: |
The caprine major histocompatibility complex (MHC) and T cell receptor variable beta chain repertoire (TCRVbeta): components of specific immune response in resistance to infectious goat diseases. |
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Ano de publicação: |
2000 |
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Fonte/Imprenta: |
In: INTERNATIONAL CONFERENCE ON GOATS, 7., 2000, Tours, Poitiers, France. Proceedings... Paris: INRA: IGA: Institut de Elevage, 2000. v. 2, p. 714-715. |
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ISBN: |
2841480399 |
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Idioma: |
Inglês |
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Conteúdo: |
The MHC is the interface where the effector cells of the adaptive immune systems meet the antigenic peptides of pathogens. The MHC is a highly polymorphic molecular complex which, differently for each individual, selects the peptides to be presented to the immune systems. This selective process determines the quality and intensity of the immune response. In this review we will present an overview of the progress achieved in characterizing the caprine MHC and its influence on the course of two infectious diseases of goats, i.e. caprine arthritis encephalitis and cowdriosis. Additionally, we will present data on the characterization ot he caprine T-cell receptor repertoire and experiments performed with MHC-monozygotic goats. The immune response of these animals to a well-defined synthetic peptide derived from the CAEV Gag protein shows the dramatic influence of the MHC on the T-cell response |
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Palavras-Chave: |
Artrite Encefalite Caprina; CAEV; Caprine arthritis encephalit virus; Complexo principal de histocompatibilidade; Resposta imunológica. |
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Thesagro: |
Caprino; Doença animal; Genética animal. |
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Thesaurus Nal: |
Goats; Immune response; Major Histocompatibility complex. |
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Categoria do assunto: |
G Melhoramento Genético |
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Marc: |
LEADER 02041naa a2200325 a 4500
001 2042429
005 2016-04-04
008 2000 bl uuuu u00u1 u #d
020 $a2841480399
100 1 $aRUFF, G. O.
245 $aThe caprine major histocompatibility complex (MHC) and T cell receptor variable beta chain repertoire (TCRVbeta)$bcomponents of specific immune response in resistance to infectious goat diseases.
260 $c2000
520 $aThe MHC is the interface where the effector cells of the adaptive immune systems meet the antigenic peptides of pathogens. The MHC is a highly polymorphic molecular complex which, differently for each individual, selects the peptides to be presented to the immune systems. This selective process determines the quality and intensity of the immune response. In this review we will present an overview of the progress achieved in characterizing the caprine MHC and its influence on the course of two infectious diseases of goats, i.e. caprine arthritis encephalitis and cowdriosis. Additionally, we will present data on the characterization ot he caprine T-cell receptor repertoire and experiments performed with MHC-monozygotic goats. The immune response of these animals to a well-defined synthetic peptide derived from the CAEV Gag protein shows the dramatic influence of the MHC on the T-cell response
650 $aGoats
650 $aImmune response
650 $aMajor Histocompatibility complex
650 $aCaprino
650 $aDoença animal
650 $aGenética animal
653 $aArtrite Encefalite Caprina
653 $aCAEV
653 $aCaprine arthritis encephalit virus
653 $aComplexo principal de histocompatibilidade
653 $aResposta imunológica
700 1 $aFLURI, A.
700 1 $aLAZARY, S.
700 1 $aVOGT, H. R.
700 1 $aPETERHANS, E.
700 1 $aBERTONI, G.
773 $tIn: INTERNATIONAL CONFERENCE ON GOATS, 7., 2000, Tours, Poitiers, France. Proceedings... Paris: INRA: IGA: Institut de Elevage, 2000.$gv. 2, p. 714-715.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 1 | |
| 1. |  | SEO, J.; OSORIO, J. S.; SCHMITT, E.; CORRÊA, M. N.; BERTONI, G.; TREVISI, E.; LOOR, J. J. Hepatic purinergic signaling gene network expression and its relationship with inflammation and oxidative stress biomarkers in blood from peripartal dairy cattle. Journal of Dairy Science, Chanpaign, v. 97, n. 2, p. 861-873, 2014.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Rondônia. |
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| Registros recuperados : 1 | |
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