Data/hora: 12/06/2024 01:59:00

Biblioteca(s): | Embrapa Amazônia Ocidental.
Data corrente: | 06/01/2022
Data da última atualização: | 10/03/2022
Autoria: | FERNANDES, K. R. P.; SOUZA, A. Q. L. de; SANTOS, L. A. dos; NOGUEIRA, F. C. S.; EVARISTO, J. A. M.; CARNEIRO, G. R. A.; SILVA, G. F. da; CRUZ, J. C. da; SOUSA, T. F.; SILVA, S. R. S. da; BASTOS, I. dos S.; ORLANDI, P. P.; SOUZA, A. D. L. de.
Afiliação: | KAMILA RANGEL PRIMO FERNANDES, UFAM; ANTONIA QUEIROZ LIMA DE SOUZA, UFAM; LANE ALENCAR DOS SANTOS, UFAM; FÁBIO CESAR SOUSA NOGUEIRA, UFRJ; JOSEPH ALBERT MEDEIROS EVARISTO, UFRJ; GABRIEL REIS ALVES CARNEIRO, UFRJ; GILVAN FERREIRA DA SILVA, CPAA; JEFERSON CHAGAS DA CRUZ, CPAA; THIAGO FERNANDES SOUSA, Bolsista CPAA; SARAH RAQUEL SILVEIRA DA SILVA, UFAM; IVANILDES DOS SANTOS BASTOS, Fiocruz Amazonia; PATRÍCIA PUCCINELLI ORLANDI, Fiocruz Amazonia; AFONSO DUARTE LEÃO DE SOUZA, UFAM.
Título: | Asperelines produced by the endophytic fungus Trichoderma asperelloides from the aquatic plant Victoria amazonica.
Ano de publicação: | 2021
Fonte/Imprenta: | Revista Brasileira de Farmacognosia, v. 31, p. 667-675, 2021.
DOI: | 10.1007/s43450-021-00215-9
Idioma: | Inglês
Conteúdo: | Asperelines, a family of linear peptides, produced by Trichoderma asperelloides, an endophytic strain from Victoria amazonica (Poepp.) J.C. Sowerby, Nymphaeaceae, are described. Fifteen asperelines with ten amino acid residues were identified by liquid chromatography coupled to mass spectrometry in a positive acquisition mode, using high-energy collisional dissociation. Eight of these asperelines are peptaibols of the model Ac-Aib-xxx-Val-Aib-xxx-Aib-xxx-xxx-Aib-Prolinol. The other seven have the rare proline-ending sequence type: Ac-Aib-xxx-Val-Aib-xxx-Aib-Aib-xxx-Aib-Proline. Nine new asperelines were identified, together with the known asperelines A, D, E, O, U, and Z11. A chemotaxonomic significance of the findings and the name ?peptaibes? to the aspereline types ending in amino acids are suggested. The aspereline-containing fraction showed a marginal activity against Streptococcus mutans and Staphylococcus aureus. This fraction also presented high activity against the pathogenic bacteria Listeria monocytogenes, as well as a low mortality against VERO-type cells.
Palavras-Chave: | Amazonian bioresources; Aquatic endophytic fungi; Trichoderma asperelloides.
Thesagro: | Victoria Amazônica.
Categoria do assunto: | --
Registro original: | Embrapa Amazônia Ocidental (CPAA)
Exemplares: | CPAA - (38678-1) - UPC - AP - DD -  -  -  - DIS