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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agroenergia. Para informações adicionais entre em contato com cnpae.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Agroenergia. |
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Data corrente: |
04/12/2013 |
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Data da última atualização: |
21/09/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
NUNES, R. L.; SANTOS, L. L. dos; BASTIANETTO, E.; OLIVEIRA, D. A. A. de; BRASIL, B. dos S. A. F. |
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Afiliação: |
Ronaldo Luiz Nunes, UFMG; Livia Loiola dos Santos, UFMG; Eduardo Bastianetto, UFMG; Denise Aparecida Andrade de Oliveira, UFMG; BRUNO DOS SANTOS ALVES FIGUEIREDO BRASIL, CNPAE. |
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Título: |
Frequency of benzimidazole resistance in Haemonchus contortus populations isolated from buffalo, goat and sheep herds. |
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Ano de publicação: |
2013 |
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Fonte/Imprenta: |
Revista Brasileira de Parasitologia Veterinária, Jaboticabal, v. 22, n. 4, p. 1-6, 2013. |
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DOI: |
10.1590/S1984-29612013000400015. |
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Idioma: |
Inglês |
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Conteúdo: |
Anthelmintic resistance is an increasing problem that threatens livestock production worldwide. Understanding of the genetic basis of benzimidazole resistance recently allowed the development of promising molecular diagnostic tools. In this study, isolates of Haemonchus contortus obtained from goats, sheep and buffaloes raised in Brazil were screened for presence of the polymorphism Phe200Tyr in the β -tubulin 1 gene, which confers resistance to benzimidazole. The allelic frequency of the mutation conferring resistance ranged from 7% to 43%, and indicated that resistance to benzimidazole could be found in nematodes isolated from all the ruminant species surveyed. Although significant variation in the frequency of the F200Y mutation was observed between different herds or host species, no significant variation could be found in populations isolated from animals within the same herd. These findings suggest that screening of samples from a few animals has the potential to provide information about the benzimidazole resistance status of the entire herd, which would enable a considerable reduction in the costs of diagnosis for the producer. Molecular diagnosis has practical advantages, since it can guide the choice of anthelmintic drug that will be used, before its application in the herd, thus reducing the economic losses driven by anthelmintic resistance. |
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Palavras-Chave: |
Benzimidazóis; Diagnóstico molecular; Polimorfismos; Resistência a drogas anti-helmíntico; Ruminantes domésticos. |
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Thesagro: |
Genética. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02250naa a2200253 a 4500
001 1972839
005 2017-09-21
008 2013 bl uuuu u00u1 u #d
024 7 $a10.1590/S1984-29612013000400015.$2DOI
100 1 $aNUNES, R. L.
245 $aFrequency of benzimidazole resistance in Haemonchus contortus populations isolated from buffalo, goat and sheep herds.$h[electronic resource]
260 $c2013
520 $aAnthelmintic resistance is an increasing problem that threatens livestock production worldwide. Understanding of the genetic basis of benzimidazole resistance recently allowed the development of promising molecular diagnostic tools. In this study, isolates of Haemonchus contortus obtained from goats, sheep and buffaloes raised in Brazil were screened for presence of the polymorphism Phe200Tyr in the β -tubulin 1 gene, which confers resistance to benzimidazole. The allelic frequency of the mutation conferring resistance ranged from 7% to 43%, and indicated that resistance to benzimidazole could be found in nematodes isolated from all the ruminant species surveyed. Although significant variation in the frequency of the F200Y mutation was observed between different herds or host species, no significant variation could be found in populations isolated from animals within the same herd. These findings suggest that screening of samples from a few animals has the potential to provide information about the benzimidazole resistance status of the entire herd, which would enable a considerable reduction in the costs of diagnosis for the producer. Molecular diagnosis has practical advantages, since it can guide the choice of anthelmintic drug that will be used, before its application in the herd, thus reducing the economic losses driven by anthelmintic resistance.
650 $aGenética
653 $aBenzimidazóis
653 $aDiagnóstico molecular
653 $aPolimorfismos
653 $aResistência a drogas anti-helmíntico
653 $aRuminantes domésticos
700 1 $aSANTOS, L. L. dos
700 1 $aBASTIANETTO, E.
700 1 $aOLIVEIRA, D. A. A. de
700 1 $aBRASIL, B. dos S. A. F.
773 $tRevista Brasileira de Parasitologia Veterinária, Jaboticabal$gv. 22, n. 4, p. 1-6, 2013.
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Registro original: |
Embrapa Agroenergia (CNPAE) |
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| Registros recuperados : 8 | |
| 3. |  | NUNES, R. L.; SANTOS, L. L. dos; BASTIANETTO, E.; OLIVEIRA, D. A. A. de; BRASIL, B. dos S. A. F. Frequency of benzimidazole resistance in Haemonchus contortus populations isolated from buffalo, goat and sheep herds. Revista Brasileira de Parasitologia Veterinária, Jaboticabal, v. 22, n. 4, p. 1-6, 2013.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Agroenergia. |
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| 4. | | RODRIGUES, D. S.; ARAUJO, R. N.; BASTIANETTO, E.; LOPES, L. B.; KLAFKE, G. M.; FREITAS, C. M. V. de; MARTINS, J. R.; LEITE, R. C. Acaricide susceptibility of rhipicephalus (boophilus) microplus (canestrini, 1888) parasitic stages. In: CONGRESSO BRASILEIRO DE PARASITOLOGIA VETERINÁRIA, 19.; NOVEL APPROACHES TO THE CONTROL OF HELMINTH PARASITES OF LIVESTOCK, 8., 2016, Belém, PA. Anais... Jaboticabal: CBPV, 2016. Não paginado.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agrossilvipastoril. |
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| 5. | | SANTOS, L. L.; SALGADO, J. A.; DRUMMOND, M. G.; BASTIANETTO, E.; SANTOS, C. P.; BRASIL, B. dos S. A. F.; TACONELI, C. A.; OLIVEIRA, D. A. A. Molecular method for the semiquantitative identification of gastrointestinal nematodes in domestic ruminants. Parasitology Research, v. 119, p. 529-543, Feb. 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Agroenergia. |
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| 6. | | SANTOS, L. L. dos; PROSDOCIMI, F.; LIMA, N. C. B.; COSTA, I. R. da; CARDOSO, D. C.; DRUMMOND, M. G.; BRASIL, B. dos S. A. F.; BASTIANETTO, E.; OLIVEIRA, D. A. A. de. Comparative genomics and phylogenomics of Trichostrongyloidea mitochondria reveal insights for molecular diagnosis and evolutionary biology of nematode worms. Gene Reports, v. 9, p. 65-73, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 4 |
| Biblioteca(s): Embrapa Agroenergia. |
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| 7. | | CASTRO, L. L. D. de; ABRAHÃO, C. L. H.; BUZATTI, A.; MOLENTO, M. B.; BASTIANETTO, E.; RODRIGUES, D. S.; LOPES, L. B.; SILVA, M. X.; FREITAS, M. G. de; CONDE, M. H.; BORGES, F. de A. Comparison of McMaster and Mini-FLOTAC fecal egg counting techniques in cattle and horses. Veterinary Parasitology: Regional Studies and Reports, v. 10, p. 132-135, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 4 |
| Biblioteca(s): Embrapa Agrossilvipastoril. |
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| 8. | | ROCHA, A. B. da; BAGON, A.; CASTRO, C. de V. e B.; RODRIGUES, D. S.; BASTIANETTO, E.; SCHMITT, E.; SOUZA, E. P.; SCHMOELLER, E.; ANDRADE, E. R.; SANTOS, F. A. dos; LAZZARI, J.; COELHO, L. C. T.; GOUVÊA, L. V. de; LOPES, L. B.; PETRÓ, M. A.; AZEVEDO, N. C. D. de; LEITE, P. L.; LEITE, R. C. Manejo sanitário. In: SALMAN, A. K. D.; PFEIFER, L. F. M. (Ed.). Pecuária leiteira na Amazônia. Brasília, DF: Embrapa, 2020. Cap. 8. p. 143-202.| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Agrossilvipastoril. |
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| Registros recuperados : 8 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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