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![](/consulta/web/img/deny.png) | Acesso ao texto completo restrito à biblioteca da Embrapa Milho e Sorgo. Para informações adicionais entre em contato com cnpms.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Milho e Sorgo. |
Data corrente: |
18/08/2021 |
Data da última atualização: |
04/01/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MARTINEZ, O. D. M.; THEODORO, J. M. V.; GRANCIERI, M.; TOLEDO, R. C. L.; BARROS, F. A. R. de; TAKO, E.; QUEIROZ, V. A. V.; MARTINO, H. S. D. |
Afiliação: |
OSCAR DAVID MEDINA MARTINEZ, Universidade Federal de Viçosa; JAQUELINE MACIEL VIEIRA THEODORO, Universidade Federal de Viçosa; MARIANA GRANCIERI, Universidade Federal de Viçosa; RENATA CELI LOPES TOLEDO, Universidade Federal de Viçosa; FREDERICO AUGUSTO RIBEIRO DE BARROS, Universidade Federal de Viçosa; ELAD TAKO, Cornell University; VALERIA APARECIDA VIEIRA QUEIROZ, CNPMS; HÉRCIA STAMPINI DUARTE MARTINO, Universidade Federal de Viçosa. |
Título: |
Dry heated sorghum BRS 305 hybrid flour as a source of resistant starch and tannins improves inflammation and oxidative stress in Wistar rats fed with a high-fat high-fructose diet. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Food & Function, v. 12, p. 8738-8746, 2021. |
DOI: |
https://doi.org/10.1039/d1fo00802a |
Idioma: |
Inglês |
Conteúdo: |
This study aimed to evaluate the effect of dry heated sorghum BRS 305 hybrid flour, as a rich source of resistant starch and tannins, on inflammation and oxidative stress in animals fed with a high-fat high-fructose diet. Phase 1 (8 weeks): male Wistar rats were divided into a group fed with an AIN-93 M diet (n = 10) and a group fed with a high-fat (35%) high-fructose (20%) (HFHF) diet (n = 20). Phase 2 (intervention 10 weeks): the control group was continued with the AIN-93 M diet (n = 10) and the HFHF group was divided into HFHF (n = 10) and sorghum flour (n = 10) groups. Sorghum flour decreased the NO, Akt, p65-NF-4;B, TLR4, and lipid peroxidation in the liver. Furthermore, sorghum flour improved SOD and CAT activities and the total antioxidant capacity of plasma. The phenolic compounds found in sorghum flour interacted in silico with AKT and p65-NFκB, mainly quercetin-3-rutinoside that showed the highest interaction with AKT (EFE-8.0) and procyanidins B1 and B2 that showed the highest interaction with p65-NFκB (EFE −8.9). The consumption of BRS 305 sorghum with a high tannin and resistant starch content improved inflammation and oxidative stress by inhibition of p65-NF-4;B activation in rats fed a high-fat high-fructose diet. |
Thesagro: |
Amido; Farinha; Sorgo; Tanino. |
Categoria do assunto: |
Q Alimentos e Nutrição Humana |
Marc: |
LEADER 02115naa a2200265 a 4500 001 2133687 005 2022-01-04 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1039/d1fo00802a$2DOI 100 1 $aMARTINEZ, O. D. M. 245 $aDry heated sorghum BRS 305 hybrid flour as a source of resistant starch and tannins improves inflammation and oxidative stress in Wistar rats fed with a high-fat high-fructose diet.$h[electronic resource] 260 $c2021 520 $aThis study aimed to evaluate the effect of dry heated sorghum BRS 305 hybrid flour, as a rich source of resistant starch and tannins, on inflammation and oxidative stress in animals fed with a high-fat high-fructose diet. Phase 1 (8 weeks): male Wistar rats were divided into a group fed with an AIN-93 M diet (n = 10) and a group fed with a high-fat (35%) high-fructose (20%) (HFHF) diet (n = 20). Phase 2 (intervention 10 weeks): the control group was continued with the AIN-93 M diet (n = 10) and the HFHF group was divided into HFHF (n = 10) and sorghum flour (n = 10) groups. Sorghum flour decreased the NO, Akt, p65-NF-4;B, TLR4, and lipid peroxidation in the liver. Furthermore, sorghum flour improved SOD and CAT activities and the total antioxidant capacity of plasma. The phenolic compounds found in sorghum flour interacted in silico with AKT and p65-NFκB, mainly quercetin-3-rutinoside that showed the highest interaction with AKT (EFE-8.0) and procyanidins B1 and B2 that showed the highest interaction with p65-NFκB (EFE −8.9). The consumption of BRS 305 sorghum with a high tannin and resistant starch content improved inflammation and oxidative stress by inhibition of p65-NF-4;B activation in rats fed a high-fat high-fructose diet. 650 $aAmido 650 $aFarinha 650 $aSorgo 650 $aTanino 700 1 $aTHEODORO, J. M. V. 700 1 $aGRANCIERI, M. 700 1 $aTOLEDO, R. C. L. 700 1 $aBARROS, F. A. R. de 700 1 $aTAKO, E. 700 1 $aQUEIROZ, V. A. V. 700 1 $aMARTINO, H. S. D. 773 $tFood & Function$gv. 12, p. 8738-8746, 2021.
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Embrapa Milho e Sorgo (CNPMS) |
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![](/consulta/web/img/deny.png) | Acesso ao texto completo restrito à biblioteca da Embrapa Trigo. Para informações adicionais entre em contato com cnpt.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Trigo. |
Data corrente: |
28/08/1996 |
Data da última atualização: |
28/08/1996 |
Autoria: |
ANGRA, D. C.; PRESTES, A. M.; MARTINELLI, P.; MORAES-FERNANDES, M. I. B. de; BARCELLOS, A. L. |
Afiliação: |
2, 3-4 EMBRAPA-CNPT. |
Título: |
Reação de híbridos intergenericos do cruzamento entre trigo e Agropyron elongatum a ferrugem da folha do trigo. |
Ano de publicação: |
1996 |
Fonte/Imprenta: |
Fitopatologia Brasileira, Brasília, DF, v. 21, Supl., p. 346, ago. 1996. Resumos. |
ISSN: |
0100-4158 |
Idioma: |
Português |
Categoria do assunto: |
-- |
Marc: |
LEADER 00569naa a2200169 a 4500 001 1821736 005 1996-08-28 008 1996 bl uuuu u00u1 u #d 022 $a0100-4158 100 1 $aANGRA, D. C. 245 $aReação de híbridos intergenericos do cruzamento entre trigo e Agropyron elongatum a ferrugem da folha do trigo. 260 $c1996 700 1 $aPRESTES, A. M. 700 1 $aMARTINELLI, P. 700 1 $aMORAES-FERNANDES, M. I. B. de 700 1 $aBARCELLOS, A. L. 773 $tFitopatologia Brasileira, Brasília, DF$gv. 21, Supl., p. 346, ago. 1996. Resumos.
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