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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
07/04/2015 |
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Data da última atualização: |
26/01/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ANDREOTE, A. P. D.; ROSÁRIO, M. F. do; LEDUR, M. C.; JORGE, E. C.; SONSTEGARD, T. S.; MATUKUMALLI, L.; COUTINHO, L. L. |
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Afiliação: |
ANA PAULA DINI ANDREOTE, CENA/USP; MILLOR FERNANDES DO ROSÁRIO, ESALQ; MONICA CORREA LEDUR, CNPSA; ERIKA CRISTINA JORGE, CENA/USP; Animal Research Center/USDA; Animal Research Center/USDA; LUIS LEHMANN COUTINHO, ESALQ. |
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Título: |
Identification and characterization of microRNAs expressed in chicken skeletal muscle. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Genetics and Molecular Research, v. 6, n. 1, p. 1465-1479, 2014. |
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DOI: |
10.4238/2014.March.6.5. |
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Idioma: |
Inglês |
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Conteúdo: |
MicroRNAs (miRNAs, miRs) encompass a class of small non-coding RNAs that often negatively regulate gene expression. miRNAs play an essential role in skeletal muscle, determining the proper development and maintenance of this tissue. In comparison to other organs and tissues, the full set of muscle miRNAs and its expression patterns are still poorly understood. In this report, a chicken skeletal muscle miRNA library was constructed, and the expression of selected miRNAs was further characterized during muscle development in chicken lines with distinct muscling phenotypes. Clone library sequence analysis revealed 40 small RNAs with similarities to previously described chicken miRNAs, seven miRNAs that were never identified before in chicken, and some sequence clusters representing other possible novel miRNAs. Temporal expression profiles of three miRNAs associated with cell proliferation and differentiation (miR-125b, miR-221, and miR-206) in two chicken lines (broiler and layer) revealed the differential steady-state levels of these miRs during skeletal muscle growth and suggests that miR-206 is involved in the muscling phenotype that is observed in growth-selected chicken lines. |
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Thesagro: |
Galinha; Genetica animal. |
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Thesaurus Nal: |
Cell proliferation; Chickens; Molecular genetics. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/121936/1/final7468.pdf
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Marc: |
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001 2012924
005 2018-01-26
008 2014 bl uuuu u00u1 u #d
024 7 $a10.4238/2014.March.6.5.$2DOI
100 1 $aANDREOTE, A. P. D.
245 $aIdentification and characterization of microRNAs expressed in chicken skeletal muscle.$h[electronic resource]
260 $c2014
520 $aMicroRNAs (miRNAs, miRs) encompass a class of small non-coding RNAs that often negatively regulate gene expression. miRNAs play an essential role in skeletal muscle, determining the proper development and maintenance of this tissue. In comparison to other organs and tissues, the full set of muscle miRNAs and its expression patterns are still poorly understood. In this report, a chicken skeletal muscle miRNA library was constructed, and the expression of selected miRNAs was further characterized during muscle development in chicken lines with distinct muscling phenotypes. Clone library sequence analysis revealed 40 small RNAs with similarities to previously described chicken miRNAs, seven miRNAs that were never identified before in chicken, and some sequence clusters representing other possible novel miRNAs. Temporal expression profiles of three miRNAs associated with cell proliferation and differentiation (miR-125b, miR-221, and miR-206) in two chicken lines (broiler and layer) revealed the differential steady-state levels of these miRs during skeletal muscle growth and suggests that miR-206 is involved in the muscling phenotype that is observed in growth-selected chicken lines.
650 $aCell proliferation
650 $aChickens
650 $aMolecular genetics
650 $aGalinha
650 $aGenetica animal
700 1 $aROSÁRIO, M. F. do
700 1 $aLEDUR, M. C.
700 1 $aJORGE, E. C.
700 1 $aSONSTEGARD, T. S.
700 1 $aMATUKUMALLI, L.
700 1 $aCOUTINHO, L. L.
773 $tGenetics and Molecular Research$gv. 6, n. 1, p. 1465-1479, 2014.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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| Registros recuperados : 2 | |
| 1. |  | ANDREOTE, A. P. D.; ROSÁRIO, M. F. do; LEDUR, M. C.; JORGE, E. C.; SONSTEGARD, T. S.; MATUKUMALLI, L.; COUTINHO, L. L. Identification and characterization of microRNAs expressed in chicken skeletal muscle. Genetics and Molecular Research, v. 6, n. 1, p. 1465-1479, 2014.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Suínos e Aves. |
|    |
| 2. | | NINOV, K.; MOURÃO, G. B.; ANDREOTE, A. P. D.; JORGE, E. C.; VILLELA, P. M. S.; LEDUR, M. C.; COUTINHO, L. L. Seleção de genes referência para RT-PCRq durante o desenvolvimento da musculatura esquelética de galinhas In: CONGRESSO BRASILEIRO DE GENÉTICA, 55, 2009, Águas de Lindóia. Anais... Águas de Lindóia:SBG, 2009. p. 154. Projeto/Plano de Ação: 01.06.106.03-05| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| Registros recuperados : 2 | |
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