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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
29/10/2021 |
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Data da última atualização: |
29/10/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
FAYER, L.; ZANETTE, R. S. S.; SIQUEIRA, J. T. C.; OLIVEIRA, E. R.; ALMEIDA, C. G.; GERN, J. C.; SOUSA, S. M.; OLIVEIRA, L. R. C. de; BRANDAO, H. de M.; MUNK, M. |
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Afiliação: |
LEONARA FAYER, Universidade Federal de juiz de Fora; RAFAELLA S. S. ZANETTE, Universidade Federal de Juiz de Fora; JULIANA T. C. SIQUEIRA, Universidade Federal de Juiz de Fora; EDUARDA R. OLIVEIRA, Universidade Federal de Juiz de Fora; CAMILA G. ALMEIDA; JULIANA CARINE GERN, CNPGL; SAULO M. SOUSA, Universidade Federal de Juiz de Fora; LUIZ F. C. DE OLIVEIRA, Universidade Federal de Juiz de Fora; HUMBERTO DE MELLO BRANDAO, CNPGL; MICHELE MUNK, Universidade Federal de Juiz de Fora. |
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Título: |
The distinct effect of titanium dioxide nanoparticles in primary and immortalized cell lines. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Toxicology Research, v. 10, n. 3, p. 511-522, 2021. |
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DOI: |
https://doi.org/10.1093/toxres/tfab040 |
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Idioma: |
Inglês |
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Conteúdo: |
The titanium dioxide nanoparticles (NPs) have been applied to biomedical, pharmaceutical, and food additive fields. However, the effect on health and the environment are conf licting; thus, it has been reviewing several times. In this context, establishing standard robust protocols for detecting cytotoxicity and genotoxicity of nanomaterials became essential for nanotechnology development. The cell type and the intrinsic characteristics of titanium dioxide NPs can inf luence nanotoxicity. In this work, the cyto- and genotoxicity effects of standard reference material titanium dioxide NPs in primary bovine fibroblasts and immortalized Chinese hamster ovary epithelial (CHO) cells were determined and compared for the first time. Titanium dioxide NPs exposure revealed no cytotoxicity for primary bovine fibroblasts, while only higher concentrations tested (10 ?g/ml) induce genotoxic effects in this cell model. In contrast, the lower concentrations of the titanium dioxide NPs cause the cyto- and genotoxic effects in CHO cells. Therefore, our finding indicates that the CHO line was more sensitive toward the effects of titanium dioxide NPs than the primary bovine fibroblast, which should be valuable for their environmental risk assessment. |
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Palavras-Chave: |
Avaliação de risco; Célula CHO; Fibroblasto; Nanomaterial; Nanotoxicidade. |
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Thesagro: |
Bovino. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02160naa a2200313 a 4500
001 2135714
005 2021-10-29
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1093/toxres/tfab040$2DOI
100 1 $aFAYER, L.
245 $aThe distinct effect of titanium dioxide nanoparticles in primary and immortalized cell lines.$h[electronic resource]
260 $c2021
520 $aThe titanium dioxide nanoparticles (NPs) have been applied to biomedical, pharmaceutical, and food additive fields. However, the effect on health and the environment are conf licting; thus, it has been reviewing several times. In this context, establishing standard robust protocols for detecting cytotoxicity and genotoxicity of nanomaterials became essential for nanotechnology development. The cell type and the intrinsic characteristics of titanium dioxide NPs can inf luence nanotoxicity. In this work, the cyto- and genotoxicity effects of standard reference material titanium dioxide NPs in primary bovine fibroblasts and immortalized Chinese hamster ovary epithelial (CHO) cells were determined and compared for the first time. Titanium dioxide NPs exposure revealed no cytotoxicity for primary bovine fibroblasts, while only higher concentrations tested (10 ?g/ml) induce genotoxic effects in this cell model. In contrast, the lower concentrations of the titanium dioxide NPs cause the cyto- and genotoxic effects in CHO cells. Therefore, our finding indicates that the CHO line was more sensitive toward the effects of titanium dioxide NPs than the primary bovine fibroblast, which should be valuable for their environmental risk assessment.
650 $aBovino
653 $aAvaliação de risco
653 $aCélula CHO
653 $aFibroblasto
653 $aNanomaterial
653 $aNanotoxicidade
700 1 $aZANETTE, R. S. S.
700 1 $aSIQUEIRA, J. T. C.
700 1 $aOLIVEIRA, E. R.
700 1 $aALMEIDA, C. G.
700 1 $aGERN, J. C.
700 1 $aSOUSA, S. M.
700 1 $aOLIVEIRA, L. R. C. de
700 1 $aBRANDAO, H. de M.
700 1 $aMUNK, M.
773 $tToxicology Research$gv. 10, n. 3, p. 511-522, 2021.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
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Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Cerrados. |
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Data corrente: |
16/05/2022 |
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Data da última atualização: |
16/05/2022 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
SOUZA, K. W. de; CALAÇA, J. C. P.; SANTOS, F. A. dos; PULROLNIK, K.; RAMOS, M. L. G.; RIBEIRO JUNIOR, W. Q.; CARVALHO, A. M. de. |
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Afiliação: |
KLEBERSON WORSLLEY DE SOUZA, CPAC; JULIANE CRISTINA PEREIRA CALAÇA; FELIPE ALVES DOS SANTOS; KARINA PULROLNIK, CPAC; MARIA LUCRÉCIA GEROSA RAMOS; WALTER QUADROS RIBEIRO JUNIOR, CPAC; ARMINDA MOREIRA DE CARVALHO, CPAC. |
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Título: |
Effect of integrated soybean with sorghum and brachiaria system on soil carbon and nitrogen. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
In: WORLD CONGRESS ON INTEGRATED CROP-LIVESTOCK-FORESTRY SYSTEMS: 100% DIGITAL, 2., 2021. Proceedings... Campo Grande: Embrapa Gado de Corte, 2021. |
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Páginas: |
p. 358-364 |
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Idioma: |
Inglês |
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Conteúdo: |
The objective of this work was to analyze the effect of the integrated soybean system with sorghum and brachiaria on the levels of organic carbon, total N and mineral N in the soil. Super short cycle soybean BRS 7580 was planted, and subsequently, forage sorghum BRS 655 and BRS Piatã brachiaria were planted between the lines of the soybean. The levels of organic carbon, total nitrogen, ammonium, nitrate and mineral nitrogen/total nitrogen ratio were evaluated. The soil under Cerrado showed higher levels of organic carbon at all depths. There were no significant differences between treatments and the Cerrado for total nitrogen content in the deepest layers of the soil. All treatments showed a stratified distribution for the ammonium content, with higher values in the more superficial layers, decreasing in the deeper layers. Nitrate was not detected in the soil under Cerrado. Integrated crop treatments showed higher nitrate values than singles systems. In general, nitrate values were higher in the more superficial layers, with a significant decrease in the intermediate layers, increasing again in the 40-60 cm layer. The mineral nitrogen/total nitrogen ratio treatments with single or intercropped soybean maintained the same nitrate results pattern. |
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Palavras-Chave: |
Agroecossistema; Sistema consorciado. |
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Thesagro: |
Carbono; Cerrado; Nitrato; Soja. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1142990/1/Kleberson-Congresso-Effect-of-integrated-soybean-with-sorghum.pdf
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Marc: |
LEADER 02123nam a2200265 a 4500
001 2142990
005 2022-05-16
008 2021 bl uuuu u00u1 u #d
100 1 $aSOUZA, K. W. de
245 $aEffect of integrated soybean with sorghum and brachiaria system on soil carbon and nitrogen.$h[electronic resource]
260 $aIn: WORLD CONGRESS ON INTEGRATED CROP-LIVESTOCK-FORESTRY SYSTEMS: 100% DIGITAL, 2., 2021. Proceedings... Campo Grande: Embrapa Gado de Corte$c2021
300 $ap. 358-364
520 $aThe objective of this work was to analyze the effect of the integrated soybean system with sorghum and brachiaria on the levels of organic carbon, total N and mineral N in the soil. Super short cycle soybean BRS 7580 was planted, and subsequently, forage sorghum BRS 655 and BRS Piatã brachiaria were planted between the lines of the soybean. The levels of organic carbon, total nitrogen, ammonium, nitrate and mineral nitrogen/total nitrogen ratio were evaluated. The soil under Cerrado showed higher levels of organic carbon at all depths. There were no significant differences between treatments and the Cerrado for total nitrogen content in the deepest layers of the soil. All treatments showed a stratified distribution for the ammonium content, with higher values in the more superficial layers, decreasing in the deeper layers. Nitrate was not detected in the soil under Cerrado. Integrated crop treatments showed higher nitrate values than singles systems. In general, nitrate values were higher in the more superficial layers, with a significant decrease in the intermediate layers, increasing again in the 40-60 cm layer. The mineral nitrogen/total nitrogen ratio treatments with single or intercropped soybean maintained the same nitrate results pattern.
650 $aCarbono
650 $aCerrado
650 $aNitrato
650 $aSoja
653 $aAgroecossistema
653 $aSistema consorciado
700 1 $aCALAÇA, J. C. P.
700 1 $aSANTOS, F. A. dos
700 1 $aPULROLNIK, K.
700 1 $aRAMOS, M. L. G.
700 1 $aRIBEIRO JUNIOR, W. Q.
700 1 $aCARVALHO, A. M. de
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