Data/hora: 21/06/2024 19:47:05

Biblioteca(s): 	Embrapa Agroindústria de Alimentos.	
Data corrente: 	27/01/2021	
Data da última atualização: 	15/06/2021	
Autoria: 	FRAUCHES, N. S.; MONTENEGRO, J.; AMARAL, T.; ABREU, J. P.; LAIBER, G.; JORGE JUNIOR; BORGUINI, R. G.; SANTIAGO, M. C. P. de A.; PACHECO, S.; NAKAJIMA, V. M.; GODOY, R. L. de O.; TEODORO, A. J.	
Afiliação: 	Nayara Simas Frauches, UNIRIO; Júlia Montenegro, UNIRIO; Thuane Amaral, UNIRIO; Joel Pimentel Abreu, UNIRIO; Gabriela Laiber, UNIRIO; Jorge Junior, UFRJ; RENATA GALHARDO BORGUINI, CTAA; MANUELA CRISTINA P DE A SANTIAGO, CTAA; SIDNEY PACHECO, CTAA; Vania Mayumi Nakajima, UFF; RONOEL LUIZ DE OLIVEIRA GODOY, CTAA; Anderson Junger Teodoro, UNIRIO.	
Título: 	Antiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family.	
Ano de publicação: 	2021	
Fonte/Imprenta: 	Molecules, v. 26, n. 564 , 2021. p. 1-16.	
DOI: 	https://doi.org/10.3390/molecules26030564	
Idioma: 	Inglês	
Conteúdo: 	There is a significant indication of the beneficial health effects of fruit rich diets. Fruitsof native plant species have noticeably different phytochemicals and bioactive effects. The aim ofthis work was to characterize and compare the constituents of jabuticaba (Myrciaria jaboticaba, MJ),jamun-berry (Syzygium cumini, SC), and malay-apple (Syzygium malaccense, SM) extracts and theirinfluence on antioxidant activityin vitroand antiproliferative effects on human colon adenocarci-noma cells. According to the results, dried peel powders (DP) have a high anthocyanin content,phenolic compounds, and antioxidant activity when compared to freeze dried extracts (FD).M.jaboticabadried peel powder extract had a higher total anthocyanin and phenolic compounds content(802.90±1.93 and 2152.92±43.95 mg/100 g, respectively). A reduction in cell viability of HT-29cells after treatment withM. jaboticabaextracts (DP-MJ and FD-MJ) was observed via MTT assay.Flow cytometry showed that the treatment with the anthocyanin-rich extracts from MJ, SC, and SMhad an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cellsin relation to the control group. The findings of this study highlight the potential of peel powdersfromMyrtaceaefruits as an important source of natural antioxidants and a protective effect againstcolon adenocarcinoma	
Palavras-Chave: 	Colon cancer; Jamun-berry; Malay-apple; Myrtaceae fruits.	
Thesagro: 	Jabuticaba.	
Thesaurus Nal: 	Bioactive compounds.	
Categoria do assunto: 	X Pesquisa, Tecnologia e Engenharia	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/220691/1/molecules-26-00564.pdf	
Registro original: 	Embrapa Agroindústria de Alimentos (CTAA)	
Exemplares: 	CTAA - (15121-1) - UPC - AP - DD -  -  -  - DIS