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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
24/06/1997 |
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Data da última atualização: |
18/07/2023 |
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Autoria: |
McGUIRE, T. C.; KNOWLES JUNIOR, D. P.; DAVIS, W. C.; BRASSFIELD, A. L.; STEM, T. A.; CHEEVERS, W. P. |
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Título: |
Transmembrane protein oligomers of caprine arthritis-encephalitis lentivirus are immunodominant in goats with progressive arthritis. |
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Ano de publicação: |
1992 |
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Fonte/Imprenta: |
Journal Virology, v. 66, n. 5, p. 3247-3250, May, 1992. |
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DOI: |
10.1128/JVI.66.5.3247-3250.1992. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: To dissect mechanisms of caprine arthritis-encephalitis lentivirus-induced arthritis, an undefined immunodominant viral glycoprotein, gp90 (G. C. Johnson, A. F. Barbet, P. Klevjer-Anderson, and T. C. McGuire, Infect. Immun. 41:657-665, 1983), was characterized. Monoclonal antibody to gp90 and specific antiserum to env gene products demonstrated that gp90 was a transmembrane protein (TM) dimer. Goats with progressive arthritis had high antibody titers to oligomeric and monomeric (38-kDa) TM. |
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Palavras-Chave: |
CAEV; Proteinas. |
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Thesagro: |
Artrite. |
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Thesaurus Nal: |
Caprine arthritis encephalitis virus; Glycoproteins; Glycosylation; Goat diseases; Goats; Immunodominant epitopes; Immunology; Lentivirus; Monoclonal antibodies. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
null
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
